Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Miguel A Pérez-Castro"'
Autor:
Hasier Eraña, Cristina Sampedro-Torres-Quevedo, Jorge M. Charco, Carlos M. Díaz-Domínguez, Francesca Peccati, Maitena San-Juan-Ansoleaga, Enric Vidal, Nuno Gonçalves-Anjo, Miguel A. Pérez-Castro, Ezequiel González-Miranda, Patricia Piñeiro, Leire Fernández-Veiga, Josu Galarza-Ahumada, Eva Fernández-Muñoz, Guiomar Perez de Nanclares, Glenn Telling, Mariví Geijo, Gonzalo Jiménez-Osés, Joaquín Castilla
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Prion diseases are a group of rapidly progressing neurodegenerative disorders caused by the misfolding of the endogenous prion protein (PrPC) into a pathogenic form (PrPSc). This process, despite being the central event underlying these diso
Externí odkaz:
https://doaj.org/article/a04d98f58ccd4cb2b901a29e2c563eae
Autor:
Hasier Eraña, Carlos M. Díaz-Domínguez, Jorge M. Charco, Enric Vidal, Ezequiel González-Miranda, Miguel A. Pérez-Castro, Patricia Piñeiro, Rafael López-Moreno, Cristina Sampedro-Torres-Quevedo, Leire Fernández-Veiga, Juan Tasis-Galarza, Nuria L. Lorenzo, Aileen Santini-Santiago, Melisa Lázaro, Sandra García-Martínez, Nuno Gonçalves-Anjo, Maitena San-Juan-Ansoleaga, Josu Galarza-Ahumada, Eva Fernández-Muñoz, Samanta Giler, Mikel Valle, Glenn C. Telling, Mariví Geijó, Jesús R. Requena, Joaquín Castilla
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-30 (2023)
Abstract Among transmissible spongiform encephalopathies or prion diseases affecting humans, sporadic forms such as sporadic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms of the disease, these idiopathic forms oc
Externí odkaz:
https://doaj.org/article/63c13fcaea6249e3a04b3b8cea76b3ad
Autor:
Enric Vidal, Manuel A. Sánchez-Martín, Hasier Eraña, Sonia Pérez Lázaro, Miguel A. Pérez-Castro, Alicia Otero, Jorge M. Charco, Belén Marín, Rafael López-Moreno, Carlos M. Díaz-Domínguez, Mariví Geijo, Montserrat Ordóñez, Guillermo Cantero, Michele di Bari, Nuria L. Lorenzo, Laura Pirisinu, Claudia d’Agostino, Juan María Torres, Vincent Béringue, Glenn Telling, Juan J. Badiola, Martí Pumarola, Rosa Bolea, Romolo Nonno, Jesús R. Requena, Joaquín Castilla
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective breeding or other strategies as it is d
Externí odkaz:
https://doaj.org/article/ec75bdeb108f452fac8587687f697f39
Autor:
Miguel Ángel Pérez-Castro, Gal Eyal, Gerardo Esteban Leyte-Morales, Gustavo Hinojosa-Arango, Susana Enríquez
Publikováno v:
Diversity, Vol 15, Iss 4, p 531 (2023)
The distinction between shallow coral reefs and mesophotic coral ecosystems (MCEs) has not been fully clarified yet. The original definition of MCEs, by depths of 30–150 m, fixes their bathymetrical limits and fails to accommodate environmental and
Externí odkaz:
https://doaj.org/article/081f0a6e0c914e6bb5009b37df129eee
A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures
Autor:
Hasier Eraña, Miguel Ángel Pérez-Castro, Sandra García-Martínez, Jorge M. Charco, Rafael López-Moreno, Carlos M. Díaz-Dominguez, Tomás Barrio, Ezequiel González-Miranda, Joaquín Castilla
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Transmissible spongiform encephalopathies (TSEs) are a group of invariably fatal neurodegenerative disorders. The causal agent is an aberrantly folded isoform (PrPSc or prion) of the endogenous prion protein (PrPC) which is neurotoxic and amyloidogen
Externí odkaz:
https://doaj.org/article/3c7fb0c2119346d5957b782f69517a20
Autor:
Hasier Eraña, Jorge M Charco, Michele A Di Bari, Carlos M Díaz-Domínguez, Rafael López-Moreno, Enric Vidal, Ezequiel González-Miranda, Miguel A Pérez-Castro, Sandra García-Martínez, Susana Bravo, Natalia Fernández-Borges, Mariví Geijo, Claudia D'Agostino, Joseba Garrido, Jifeng Bian, Anna König, Boran Uluca-Yazgi, Raimon Sabate, Vadim Khaychuk, Ilaria Vanni, Glenn C Telling, Henrike Heise, Romolo Nonno, Jesús R Requena, Joaquín Castilla
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008117 (2019)
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to certain particularities of thes
Externí odkaz:
https://doaj.org/article/215467d1d4f44efeb809d884605f8666
Autor:
Hasier Eraña, Jorge M. Charco, Ezequiel González-Miranda, Sandra García-Martínez, Rafael López-Moreno, Miguel A. Pérez-Castro, Carlos M. Díaz-Domínguez, Adrián García-Salvador, Joaquín Castilla
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 469 (2020)
Transmissible spongiform encephalopathies or prion diseases are rapidly progressive neurodegenerative diseases, the clinical manifestation of which can resemble other promptly evolving neurological maladies. Therefore, the unequivocal ante-mortem dia
Externí odkaz:
https://doaj.org/article/d6e2c3fac5224b7ca6a60d632f2da99b
Autor:
John D. Hedley, Brandon J. Russell, Kaylan Randolph, Miguel Á. Pérez-Castro, Román M. Vásquez-Elizondo, Susana Enríquez, Heidi M. Dierssen
Publikováno v:
Frontiers in Marine Science, Vol 4 (2017)
The capability for mapping two species of seagrass, Thalassia testudinium and Syringodium filiforme, by remote sensing using a physics based model inversion method was investigated. The model was based on a three-dimensional canopy model combined wit
Externí odkaz:
https://doaj.org/article/a5a9f328544148b3bfaa1e73f2dc1547
Autor:
Miguel Ángel Pérez-Castro, Gal Eyal
In the Eastern Tropical Pacific (ETP), Mesophotic Coral Ecosystems (MCEs) are limited by oceanographic conditions and are thought to be mostly absent. However, considering the currently discussed more flexible approach to define mesophotic boundaries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::d92adfee10927a97971a34b8246b5419
https://zenodo.org/record/7094894
https://zenodo.org/record/7094894
Autor:
Jorge M. Charco, Belén Pintado, Miguel A. Pérez-Castro, Manuel Sánchez-Martín, Tomás Mayoral, Hasier Eraña, Joaquín Castilla, Enric Vidal, Martí Pumarola, Montserrat Ordóñez, Natalia Fernández-Borges, Candace K. Mathiason, Beatriz Parra
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Unlike other species, prion disease has never been described in dogs even though they were similarly exposed to the bovine spongiform encephalopathy (BSE) agent. This resistance prompted a thorough analysis of the canine PRNP gene and the presence of