Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Miguel A, Olivencia"'
1
Akademický článek
Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertension
Autor: Maria Callejo, Daniel Morales-Cano, Miguel A. Olivencia, Gema Mondejar-Parreño, Bianca Barreira, Olga Tura-Ceide, Victor G. Martínez, Alvaro Serrano-Navarro, Laura Moreno, Nick Morrell, Frédéric Perros, Angeles Vicente, Angel Cogolludo, Francisco Perez-Vizcaino
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Vitamin D (vitD) deficiency is frequently observed in patients with pulmonary arterial hypertension (PAH) and, in these patients, low levels of vitD correlate with worse prognosis. The aim of this study was to examine the expression and the
Externí odkaz: https://doaj.org/article/fa920e63fd7a42c59535f8317860e93e
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2
Akademický článek
Hydrogen sulfide regulates the redox state of soluble guanylate cyclase in CSE-/- mice corpus cavernosum microcirculation
Autor: Miguel A. Olivencia, Erika Esposito, Vincenzo Brancaleone, Sigismondo Castaldo, Giuseppe Cirino, Francisco Pérez-Vizcaino, Raffaella Sorrentino, Roberta d'Emmanuele di Villa Bianca, Emma Mitidieri
Publikováno v: Pharmacological Research, Vol 194, Iss , Pp 106834- (2023)
The corpus cavernosum (CC) is a highly vascularized tissue and represents an excellent example of microcirculation. Indeed, erectile dysfunction is considered an early index of cardiovascular disease. Hydrogen sulfide (H2S) at the vascular level is e
Externí odkaz: https://doaj.org/article/813df3742a4845d8bdea14b981cacb57
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5
Akademický článek
Restoration of Vitamin D Levels Improves Endothelial Function and Increases TASK-Like K+ Currents in Pulmonary Arterial Hypertension Associated with Vitamin D Deficiency
Autor: Maria Callejo, Daniel Morales-Cano, Gema Mondejar-Parreño, Bianca Barreira, Sergio Esquivel-Ruiz, Miguel Angel Olivencia, Laura Moreno, Angel Cogolludo, Francisco Perez-Vizcaino
Publikováno v: Biomolecules, Vol 11, Iss 6, p 795 (2021)
Background: Vitamin D (vitD) deficiency is highly prevalent in patients with pulmonary arterial hypertension (PAH). Moreover, PAH-patients with lower levels of vitD have worse prognosis. We hypothesize that recovering optimal levels of vitD in an ani
Externí odkaz: https://doaj.org/article/bf589f58ed654b58be33bc7184d98d01
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6
Vitamin D deficiency downregulates TASK-1 channels and induces pulmonary vascular dysfunction
Autor: Juan Duarte, Grégoire Manaud, Frédéric Perros, Bianca Barreira, Laura Moreno, Gema Mondejar-Parreño, Daniel Morales-Cano, María Callejo, Sergio Esquivel-Ruiz, Francisco Perez-Vizcaino, Angel Cogolludo, Miguel A Olivencia
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 319:L627-L640
Vitamin D (VitD) receptor regulates the expression of several genes involved in signaling pathways affected in pulmonary hypertension (PH). VitD deficiency is highly prevalent in PH, and low levels are associated with poor prognosis. We investigated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4afd00390d781ae16ee9a690a2f3076
https://doi.org/10.1152/ajplung.00475.2019
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8
Kv1.3 channels are novel determinants of macrophage-dependent endothelial dysfunction in angiotensin II-induced hypertension in mice
Autor: Mercedes Salaices, Angel Cogolludo, Ana M. Briones, Carmen Valenzuela, Marta Martínez-Casales, Ana B. García-Redondo, Michael W Pennington, Diego A. Peraza, Gema Mondejar-Parreño, Raquel Hernanz, Miguel A Olivencia
Publikováno v: Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
[Background and Purpose]: KV1.3 channels are expressed in vascular smooth muscle cells (VSMCs), where they contribute to proliferation rather than contraction and participate in vascular remodelling. KV1.3 channels are also expressed in macrophages,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d1ab1e82d7916748336a4a779e09b6
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9
Restoration of Vitamin D Levels Improves Endothelial Function and Increases TASK-Like K+ Currents in Pulmonary Arterial Hypertension Associated with Vitamin D Deficiency
Autor: Francisco Perez-Vizcaino, Bianca Barreira, Daniel Morales-Cano, Laura Moreno, Miguel A Olivencia, Angel Cogolludo, María Callejo, Sergio Esquivel-Ruiz, Gema Mondejar-Parreño
Publikováno v: E-Prints Complutense. Archivo Institucional de la UCM
instname
Biomolecules
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 795, p 795 (2021)
Background: Vitamin D (vitD) deficiency is highly prevalent in patients with pulmonary arterial hypertension (PAH). Moreover, PAH-patients with lower levels of vitD have worse prognosis. We hypothesize that recovering optimal levels of vitD in an ani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f55b2fad41d94eeeb0d275efa4a3f0
https://eprints.ucm.es/id/eprint/70832/1/biomolecules-11-00795-v3.pdf
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10
Uncovered contribution of Kv7 channels to pulmonary vascular tone in pulmonary arterial hypertension
Autor: Angel Cogolludo, María Callejo, Bianca Barreira, Gema Mondejar-Parreño, Daniel Morales-Cano, Laura Moreno, Sergio Esquivel-Ruiz, Miguel A Olivencia, Iain A. Greenwood, Vincenzo Barrese, Miguel Macías, Francisco Perez-Vizcaino
K + channels play a fundamental role regulating membrane potential of pulmonary artery (PA) smooth muscle cells and their impairment is a common feature in pulmonary arterial hypertension (PAH). K + voltage-gated channel subfamily Q ( KCNQ1-5 ) or Kv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b690ee01c850ce88deb79a8e957b7c
http://hdl.handle.net/11588/832022
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