Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Miguel Ángel Morcillo Alonso"'
Autor:
Erika Serrano del Pozo, Christopher Fiore, Miguel Ángel Morcillo Alonso, Loïka Maltais, Sílvia Casacuberta-Serra, Marie-Eve Beaulieu, Danny Létourneau, Laura Soucek, Génesis Martín, Peter B. Rahl, Laia Foradada, Marta Oteo, Sandra Martínez-Martín, Eduardo Romero Sanz, Jonathan Whitfield, Virginia Castillo Cano, Toni Jauset, Matthew G. Guenther, Martin Montagne, Cynthia Tremblay, Meritxell Sánchez-Hervás, Daniel Massó-Vallés, Pierre Lavigne, Mariano F. Zacarias-Fluck
Publikováno v:
Science Translational Medicine
Inhibiting MYC has long been considered unfeasible, although its key role in human cancers makes it a desirable target for therapeutic intervention. One reason for its perceived undruggability was the fear of catastrophic side effects in normal tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838a2606846d8f28f615b511b20d8cee
Autor:
Christopher Fiore, Peter B. Rahl, Marta Oteo Vives, Matthew G. Guenther, Daniel Massó-Vallés, Miguel Ángel Morcillo Alonso, Martin Montagne, Sandra Martínez-Martín, Cynthia Tremblay, Pierre Lavigne, Jonathan Whitfield, Mariano F. Zacarias-Fluck, Marie-Eve Beaulieu, Laura Soucek, Loïka Maltais, Laia Foradada, Erika Serrano del Pozo, Toni Jauset, Silvia Casacuberta, Eduardo Romero Sanz
Publikováno v:
Cancer Research. 77:2167-2167
Deregulation of the MYC oncoprotein promotes tumorigenesis in most, if not all, cancers and is often associated with poor prognosis. However, targeting MYC has long been considered impossible based on the assumption that it would cause catastrophic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23c04251b4bd6ac63a284283f992ae0
https://doi.org/10.1158/1538-7445.am2017-2167
https://doi.org/10.1158/1538-7445.am2017-2167