Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Miguel Álvaro‐Benito"'
Autor:
Miriam Bertazzon, Almudena Hurtado-Pico, Carlos Plaza-Sirvent, Marc Schuster, Marco Preußner, Benno Kuropka, Fan Liu, Andor Zenon Amandus Kirsten, Xiao Jakob Schmitt, Benjamin König, Miguel Álvaro-Benito, Esam T. Abualrous, Gesa I. Albert, Stefanie Kliche, Florian Heyd, Ingo Schmitz, Christian Freund
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The question whether interference with the ubiquitous splicing machinery can lead to cell-type specific perturbation of cellular function is addressed here by T cell specific ablation of the general U5 snRNP assembly factor CD2BP2/U5–52K. This prot
Externí odkaz:
https://doaj.org/article/5bb2494462e24f849a03eadf17761b60
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Type 1 diabetes is an autoimmune disease with rising incidence in high-income countries. Genetic and environmental predisposing factors contribute to the etiology of the disease, although their interaction is not sufficiently understood to allow for
Externí odkaz:
https://doaj.org/article/f637f9fec47c49028fd3c6e7e45cb995
Autor:
Marek Wieczorek, Jana Sticht, Sebastian Stolzenberg, Sebastian Günther, Christoph Wehmeyer, Zeina El Habre, Miguel Álvaro-Benito, Frank Noé, Christian Freund
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
MHCII proteins bind and present both foreign and self-antigens to potentially activate CD4+ T cells via cognate T cell receptors (TCRs) during the adaptive immune response. Here, the authors combine NMR-detected H/D exchange with Markov modelling ana
Externí odkaz:
https://doaj.org/article/885b930885fb44358b5880c82938cbe4
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The major histocompatibility complex of class II (MHCII) immunopeptidome represents the repertoire of antigenic peptides with the potential to activate CD4+ T cells. An understanding of how the relative abundance of specific antigenic epitopes affect
Externí odkaz:
https://doaj.org/article/24741be0b97b4836ad5788bcc5005daa
Autor:
Esam T. Abualrous, Sebastian Stolzenberg, Jana Sticht, Marek Wieczorek, Yvette Roske, Matthias Günther, Steffen Dähn, Benedikt B. Boesen, Marcos Martínez Calvo, Charlotte Biese, Frank Kuppler, Álvaro Medina-García, Miguel Álvaro-Benito, Thomas Höfer, Frank Noé, Christian Freund
Publikováno v:
Nature Chemical Biology.
Presentation of antigenic peptides by major histocompatibility complex class II (MHC-II) proteins determines T helper cell reactivity. The MHC-II genetic locus displays a large degree of allelic polymorphism influencing the peptide repertoire present
Publikováno v:
Computational Vaccine Design ISBN: 9781071632383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f631b49ce47cad466c13ff078d97be24
https://doi.org/10.1007/978-1-0716-3239-0_6
https://doi.org/10.1007/978-1-0716-3239-0_6
Autor:
Mathias Dimde, Jens Dernedde, Stefanie Wedepohl, Ann-Cathrin Schmitt, Rainer Haag, Miguel Álvaro-Benito, Felix Reisbeck, Christian Freund
Publikováno v:
Journal of Materials Chemistry B. 10:96-106
The concept of multivalency finds various applications in the fields of chemistry and biology, relying on the principle that multiple weak interactions can lead to strong adhesive forces. Polymeric carriers are promising tools to translate these prop
Autor:
Miguel Álvaro-Benito
Identifying causal genetic variants for a given phenotype improves diagnosis and provides insights for designing therapies. However, defining the link and/or contribution to a phenotype of rare variants or those with an indirect contribution to disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726e2578904326ac3544823746aefb15
Autor:
Rizwan Ahmad, Haseeb Ahsan, Miguel Álvaro-Benito, Luis M. Amezcua-Guerra, Amit Awasthi, Enrico Brunetta, Matthew C. Cook, Claudio Costantini, Syrine Daadaa, Rajdeep Dalal, Mohanad Elfishawi, Sally Elfishawi, Marco Folci, Ting Gan, Mohammad Yusuf Hasan, Tatsuo Ito, Eddie A James, Trine N. Jorgensen, Melek Kechida, Emma J. Keller, Naoko Kumagai-Takei, Vijay Kumar, Masayasu Kusaka, Suni Lee, Aifen Lin, Mauricio Mora-Ramírez, Yasumitsu Nishimura, Takemi Otsuki, Neeva B. Patel, Valentina Pucino, Giacomo Ramponi, Nima Rezaei, Nagisa Sada, Srikanth Sadhu, Yurika Shimizu, Bandaru Srinivas, Kozo Urakami, Adrian Zelada Valdes, Hui-Hui Xu, Shoko Yamamoto, Wei-Hua Yan, Niloufar Yazdanpanah, Xu-jie Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386f723a0e05e260770cb65014c98c6d
https://doi.org/10.1016/b978-0-12-822564-6.09989-4
https://doi.org/10.1016/b978-0-12-822564-6.09989-4
Autor:
Miguel Álvaro-Benito
Publikováno v:
Translational Autoimmunity ISBN: 9780128225646
Translational Autoimmunity
Translational Autoimmunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851e13e91af22e5ab3a500d01fd383d6
https://doi.org/10.1016/b978-0-12-822564-6.00003-3
https://doi.org/10.1016/b978-0-12-822564-6.00003-3