Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miguel Á. Valderrama-Gómez"'
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101200- (2020)
Summary: Mechanistic models of biochemical systems provide a rigorous description of biological phenomena. They are indispensable for making predictions and elucidating biological design principles. To date, mathematical analysis and characterization
Externí odkaz:
https://doaj.org/article/8436761400fe4e2eac6e7a68c9b4b2bf
Autor:
Gina M. Turco, Joel Rodriguez-Medina, Stefan Siebert, Diane Han, Miguel Á. Valderrama-Gómez, Hannah Vahldick, Christine N. Shulse, Benjamin J. Cole, Celina E. Juliano, Diane E. Dickel, Michael A. Savageau, Siobhan M. Brady
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 342-351.e4 (2019)
Summary: Plant xylem cells conduct water and mineral nutrients. Although most plant cells are totipotent, xylem cells are unusual and undergo terminal differentiation. Many genes regulating this process are well characterized, including the Vascular-
Externí odkaz:
https://doaj.org/article/3513be96cef044f2a3f825673ba2387f
Publikováno v:
Metabolic Engineering. 72:365-375
Phenotype-centric modeling enables a paradigm shift in the analysis of mechanistic models. It brings the focus to a network's biochemical phenotypes and their relationship with measurable traits (e.g., product yields, system dynamics, signal amplific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec30ade40161b5c5493e00bb3f58038
https://doi.org/10.1016/j.ymben.2022.05.002
https://doi.org/10.1016/j.ymben.2022.05.002
Two long standing challenges in theoretical population genetics and evolution are predicting the distribution of phenotype diversity generated by mutation and available for selection and determining the interaction of mutation, selection, and drift t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43cb2acd1e626b5324bc397f47e60b5e
https://doi.org/10.1101/2021.05.27.446045
https://doi.org/10.1101/2021.05.27.446045
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101200-(2020)
iScience
iScience, vol 23, iss 6
iScience
iScience, vol 23, iss 6
Summary Mechanistic models of biochemical systems provide a rigorous description of biological phenomena. They are indispensable for making predictions and elucidating biological design principles. To date, mathematical analysis and characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e7103f86bd169eae64ac675c02bf7b
http://www.sciencedirect.com/science/article/pii/S2589004220303850
http://www.sciencedirect.com/science/article/pii/S2589004220303850
Autor:
Siobhan M. Brady, Hannah E. Vahldick, Christine N. Shulse, Diane Han, Diane E. Dickel, Michael A. Savageau, Miguel Á. Valderrama-Gómez, Benjamin J. Cole, Gina Turco, Joel Rodriguez-Medina, Celina E. Juliano, Stefan Siebert
Publikováno v:
Cell reports, vol 28, iss 2
Cell Reports, Vol 28, Iss 2, Pp 342-351.e4 (2019)
Cell Reports, Vol 28, Iss 2, Pp 342-351.e4 (2019)
Summary: Plant xylem cells conduct water and mineral nutrients. Although most plant cells are totipotent, xylem cells are unusual and undergo terminal differentiation. Many genes regulating this process are well characterized, including the Vascular-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d6412f1048d7d5363fef9a309ee2b3
https://escholarship.org/uc/item/1dn8354r
https://escholarship.org/uc/item/1dn8354r
Publikováno v:
Journal of Microbiological Methods. 175:105918
Several species of bacteria are able to modify their swimming behavior in response to chemical attractants or repellents. Methods for the quantitative analysis of bacterial chemotaxis such as quantitative capillary assays are tedious and time-consumi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28a622746fa3fe0b2c06e9d1a95040c
https://doi.org/10.1016/j.mimet.2020.105918
https://doi.org/10.1016/j.mimet.2020.105918
Publikováno v:
Journal of theoretical biology. 455
A recently developed 'phenotype-centric' modeling strategy combines four innovations with the potential to advance our understanding of complex biological systems: (1) a rigorous mathematical definition of biochemical phenotypes, (2) a method for enu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fdbdc22a75c379119f81f2e0e2de3a
https://pubmed.ncbi.nlm.nih.gov/30036529
https://pubmed.ncbi.nlm.nih.gov/30036529
Publikováno v:
Springer Protocols Handbooks ISBN: 9783662504307
Computational methods and tools are nowadays widely applied for rational Metabolic Engineering approaches. However, what is still missing are clear advices on the right order of the application of these tools. The availability of genomic information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c03a6b31e7bc71aa6b5fb11497e9d8
https://doi.org/10.1007/8623_2015_118
https://doi.org/10.1007/8623_2015_118