Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Miguel, Saceda"'
Autor:
Isabel Martínez-Lacaci, Miguel Saceda, María Piedad Menéndez-Gutierrez, Estefanía Carrasco-García, Eva Hernando, Pilar García-Morales
Supplementary Fig. S3B from Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b78382851c6cb170338ec7825582332
https://doi.org/10.1158/1535-7163.22484519
https://doi.org/10.1158/1535-7163.22484519
Autor:
Isabel Martínez-Lacaci, Miguel Saceda, María Piedad Menéndez-Gutierrez, Estefanía Carrasco-García, Eva Hernando, Pilar García-Morales
Rapamycin and its analogues are being tested as new antitumor agents. Rapamycin binds to FKBP-12 and this complex inhibits the activity of FRAP/mammalian target of rapamycin, which leads to dephosphorylation of 4EBP1 and p70 S6 kinase, resulting in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a6a7d43e4c9102c5d96c5c8ab7795d
https://doi.org/10.1158/1535-7163.c.6531437
https://doi.org/10.1158/1535-7163.c.6531437
Autor:
Isabel Martínez-Lacaci, Miguel Saceda, María Piedad Menéndez-Gutierrez, Estefanía Carrasco-García, Eva Hernando, Pilar García-Morales
Supplementary Figure Legends from Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a418780951d8a20e515e2e4574cc75ce
https://doi.org/10.1158/1535-7163.22484513.v1
https://doi.org/10.1158/1535-7163.22484513.v1
Autor:
Maria Paz Ventero, Maria Fuentes-Baile, Cristina Quereda, Elizabeth Perez-Valeciano, Cristina Alenda, Pilar Garcia-Morales, Danilo Esposito, Pilar Dorado, Victor Manuel Barbera, Miguel Saceda
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212581 (2019)
Glioblastoma multiforme (GBM) is a poor prognosis type of tumour due to its resistance to chemo and radiotherapy. SOCS1 and SOCS3 have been associated with tumour progression and response to treatments in different kinds of cancers, including GBM. In
Externí odkaz:
https://doaj.org/article/2098c7dd7bca4956bf85a9e05504ddec
CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, Induces Cell Death in Human Cancer Cells
Autor:
María Fuentes-Baile, Daniel Bello-Gil, Elizabeth Pérez-Valenciano, Jesús M. Sanz, Pilar García-Morales, Beatriz Maestro, María P. Ventero, Cristina Alenda, Víctor M. Barberá, Miguel Saceda
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 222 (2020)
D-amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids generating hydrogen peroxide, a potential producer of reactive oxygen species. In this study, we used a CLytA-DAAO chimera, both free and bound to magnetic nanoparticles, against co
Externí odkaz:
https://doaj.org/article/3dba13f83010456a9cd960f10ce5d0b0
Autor:
Leticia Mayor-López, Elena Tristante, Mar Carballo-Santana, Estefanía Carrasco-García, Silvina Grasso, Pilar García-Morales, Miguel Saceda, Juan Luján, José García-Solano, Fernando Carballo, Carlos de Torre, Isabel Martínez-Lacaci, PhD
Publikováno v:
Translational Oncology, Vol 7, Iss 5, Pp 590-604 (2014)
The use of heat shock protein 90 (Hsp90) inhibitors is an attractive antineoplastic therapy. We wanted to compare the effects of the benzoquinone 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) and the novel isoxazole resorcinol–based
Externí odkaz:
https://doaj.org/article/9569dd5d0753487a8b725daec68fab77
Autor:
Silvina Grasso, Elena Tristante, Miguel Saceda, Pablo Carbonell, Leticia Mayor-López, Mar Carballo-Santana, Estefanía Carrasco-García, Lourdes Rocamora-Reverte, Pilar García-Morales, Fernando Carballo, José A. Ferragut, Isabel Martínez-Lacaci
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 10, Pp 845-860 (2014)
Selumetinib (AZD6244, ARRY-142886) is a MEK1/2 inhibitor that has gained interest as an anti-tumour agent. We have determined the degree of sensitivity/resistance to Selumetinib in a panel of colorectal cancer cell lines using cell proliferation and
Externí odkaz:
https://doaj.org/article/41f0fc5470f7441089abe5f2f1f656c0
Publikováno v:
Cells, Vol 3, Iss 2, Pp 199-235 (2014)
Glioblastoma multiforme is the most frequent, aggressive and fatal type of brain tumor. Glioblastomas are characterized by their infiltrating nature, high proliferation rate and resistance to chemotherapy and radiation. Recently, oncologic therapy ex
Externí odkaz:
https://doaj.org/article/7cc3cd47b32f48ec9dee5ffd6251e772
Autor:
Salomé Araujo-Abad, Antonio Manresa-Manresa, Enrique Rodríguez-Cañas, María Fuentes- Baile, Pilar García-Morales, Ricardo Mallavia, Miguel Saceda, Camino de Juan Romero
Publikováno v:
Biomedicine & Pharmacotherapy. 162:114657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83c220672cef45ad47c4cd3fc086cb2
https://doi.org/10.1016/j.biopha.2023.114657
https://doi.org/10.1016/j.biopha.2023.114657
Autor:
Manuel Sánchez, Miguel Saceda
Publikováno v:
Aulas Museos y Colecciones de Ciencias Naturales. 8:119-123
Social networks are increasingly used both to disseminate science and to teach it. In fact, because of its impact at present, to the “publish or perish” another sentence must be added “get visible or vanish”. There are many examples of scient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7ed1c77ec2a6249e793ba06125840ad
https://doi.org/10.29077/aula.8.9_sanchez
https://doi.org/10.29077/aula.8.9_sanchez