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pro vyhledávání: '"Miguel, Llinás"'
Autor:
Miguel, Llinás
Publikováno v:
The protein journal. 40(4)
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9180 (2010)
PDC109 is a modular multi-domain protein with two fibronectin type II (Fn2) repeats joined by a linker. It plays a major role in bull sperm binding to the oviductal epithelium through its interactions with phosphorylcholines (PhCs), a head group of s
Externí odkaz:
https://doaj.org/article/df7ca18193974a2cb78ca4517aa1c3e4
Autor:
Miguel Llinás, Guillermo A. Bermejo
Publikováno v:
Progress in Nuclear Magnetic Resonance Spectroscopy. 56:311-328
The standard approach to nuclear magnetic resonance (NMR) protein structure determination is based on the near complete assignment of the resonances’ chemical shifts to atoms in the molecule, prior to the structure calculation [1]. Computational me
Autor:
Miguel Llinás, Seong Soo A. An, Francis J. Castellino, Marcos D. Battistel, Alexander Grishaev
Publikováno v:
Biochemistry. 48:10208-10219
The ligand binding properties of the kringle 5 (K5) domain of human plasminogen have been investigated via intrinsic tryptophan fluorescence. The oleic acid (OA) affinity for K5 was quantified, yielding an association constant K(a) approximately 2.08
Autor:
John Ionides, Anne Pajon, Tim J. Stevens, Eldon L. Ulrich, John L. Markley, Miguel Llinás, Wayne Boucher, Rasmus H. Fogh, Ernest D. Laue, Wim F. Vranken
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 59:687-696
To address data management and data exchange problems in the nuclear magnetic resonance (NMR) community, the Collaborative Computing Project for the NMR community (CCPN) created a "Data Model" that describes all the different types of information nee
Autor:
Alexander Grishaev, Miguel Llinás
Publikováno v:
Journal of Biomolecular NMR. 28:1-10
NMR frequency assignments are usually considered a prerequisite for the analysis of NOESY spectra, in turn required for the calculation of biomolecular structures. In contrast, as we propose here, relatively high numbers of unambiguous NOE identities
Autor:
Francisco M, Kovacs, Víctor, Abraira, Javier, Zamora, María, Teresa Gil del Real, Joan, Llobera, Carmen, Fernández, José Ramón, Bauza, Kunibert, Bauza, Josep, Coll, María, Cuadri, Elena, Duro, Juan, Gili, Mario, Gestoso, Marina, Gómez, Juana, González, Patricia, Ibañez, Antoni, Jover, Pablo, Lázaro, Miguel, Llinás, Catalina, Mateu, Nicole, Mufraggi, Alfonso, Muriel, Carmen, Nicolau, María Arrate, Olivera, Patricia, Pascual, Lourdes, Perelló, Francisco, Pozo, Teresa, Revuelta, Vicente, Reyes, Sebestián, Ribot, Jaime, Ripoll, Juana, Ripoll, Elena, Rodríguez
Publikováno v:
Spine. 29:206-210
Study Design. Correlation among previously validated questionnaires. Objectives. To determine the correlation between pain, disability, and quality of life in patients with low back pain. of Background Data. The Visual Analogue Scale (VAS), and the R
Publikováno v:
Biochemistry. 42:1078-1085
The alpha(2)-plasmin inhibitor (A2PI) is a main physiological regulator of the trypsin-like serine proteinase plasmin. It is composed of an N-terminal 15 amino acid fibrin cross-linking polypeptide, a 382-residue serpin domain, and a flexible C-termi
Autor:
Miguel Llinás, Alexander Grishaev
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6713-6718
The NMR-generated foc proton density affords a template to which the molecule has to be fitted to derive the structure. Here we present a computational protocol that achieves this goal. H N atoms are readily recognizable from 1 H/ 2 H exchange or 1 H
Publikováno v:
Biochemistry. 41:3302-3310
The two-domain fragment N+K1 (rNK1) [Glu(1)-Glu(163)] of human plasminogen was expressed in E. coli as a hexahistidine-tagged fusion protein and chromatographically purified. The (1)H NMR spectrum supports proper folding of the K1 component within th