Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Miguel, Burgos"'
Autor:
Alicia Hurtado, Irene Mota-Gómez, Miguel Lao, Francisca M. Real, Johanna Jedamzick, Miguel Burgos, Darío G. Lupiáñez, Rafael Jiménez, Francisco J. Barrionuevo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Mammalian sex determination is controlled by antagonistic gene cascades operating in embryonic undifferentiated gonads. The expression of the Y-linked gene SRY is sufficient to trigger the testicular pathway, whereas its absence in XX embryo
Externí odkaz:
https://doaj.org/article/06367c1b56a5499db421e47522fe087c
Autor:
Miriam Cerván-Martín, Frank Tüttelmann, Alexandra M. Lopes, Lara Bossini-Castillo, Rocío Rivera-Egea, Nicolás Garrido, Saturnino Lujan, Gema Romeu, Samuel Santos-Ribeiro, José A. Castilla, M. Carmen Gonzalvo, Ana Clavero, Vicente Maldonado, F. Javier Vicente, Sara González-Muñoz, Andrea Guzmán-Jiménez, Miguel Burgos, Rafael Jiménez, Alberto Pacheco, Cristina González, Susana Gómez, David Amorós, Jesus Aguilar, Fernando Quintana, Carlos Calhaz-Jorge, Ana Aguiar, Joaquim Nunes, Sandra Sousa, Isabel Pereira, Maria Graça Pinto, Sónia Correia, Josvany Sánchez-Curbelo, Olga López-Rodrigo, Javier Martín, Iris Pereira-Caetano, Patricia I. Marques, Filipa Carvalho, Alberto Barros, Jörg Gromoll, Lluís Bassas, Susana Seixas, João Gonçalves, Sara Larriba, Sabine Kliesch, Rogelio J. Palomino-Morales, F. David Carmona
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A GWAS in a large case-control cohort of European ancestry identifies two genomic regions, the MHC class II gene HLA-DRB1 and an upstream locus of VRK1, that are associated with the most severe phenotype of spermatogenic failure.
Externí odkaz:
https://doaj.org/article/77b3fe3532a14229aef1e788bb1d7f9d
Autor:
Andrea Guzmán-Jiménez, Sara González-Muñoz, Miriam Cerván-Martín, Rocío Rivera-Egea, Nicolás Garrido, Saturnino Luján, Samuel Santos-Ribeiro, José A. Castilla, M. Carmen Gonzalvo, Ana Clavero, F. Javier Vicente, Vicente Maldonado, Javier Villegas-Salmerón, Miguel Burgos, Rafael Jiménez, Maria Graça Pinto, Isabel Pereira, Joaquim Nunes, Josvany Sánchez-Curbelo, Olga López-Rodrigo, Iris Pereira-Caetano, Patricia Isabel Marques, Filipa Carvalho, Alberto Barros, Lluís Bassas, Susana Seixas, João Gonçalves, Alexandra M. Lopes, Sara Larriba, Rogelio J. Palomino-Morales, F. David Carmona, Lara Bossini-Castillo, IVIRMA Group, Lisbon Clinical Group
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Severe spermatogenic failure (SPGF) represents one of the most relevant causes of male infertility. This pathological condition can lead to extreme abnormalities in the seminal sperm count, such as severe oligozoospermia (SO) or non-obstr
Externí odkaz:
https://doaj.org/article/888486e3bcaf4088a22f990d7ff53f24
Autor:
María del Mar Noblejas-López, Cristina Nieto-Jiménez, Eva M. Galán-Moya, David Tebar-García, Juan Carlos Montero, Atanasio Pandiella, Miguel Burgos, Alberto Ocaña
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Background Although the anti-HER2 antibody trastuzumab augments patient survival in HER2+ breast cancer, a relevant number of patients progress to this treatment. In this context, novel drug combinations are needed to increase its antitumor
Externí odkaz:
https://doaj.org/article/27735656da444e08a86d58977135ef31
Autor:
Leyre Martínez-Fernández, Miguel Burgos, Neira Sáinz, Laura M. Laiglesia, José Miguel Arbones-Mainar, Pedro González-Muniesa, María J. Moreno-Aliaga
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 919 (2023)
This study analyses the effects of Maresin 1 (MaR1), a docosahexaenoic acid (DHA)-derived specialized proresolving lipid mediator with anti-inflammatory and insulin-sensitizing actions, on the expression of adipokines, including adiponectin, leptin,
Externí odkaz:
https://doaj.org/article/7d65026a24804d73893308a7c446152d
Autor:
Miguel Burgos, Iván Cavero-Redondo, Celia Álvarez-Bueno, Eva María Galán-Moya, Atanasio Pandiella, Eitan Amir, Alberto Ocaña
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Identification of membrane proteins differentially expressed on tumor cells is a key step in drug development. The carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is a cell adhesion protein belonging to the immunoglobu
Externí odkaz:
https://doaj.org/article/43dce86e5c974886adb6b471146da52d
Autor:
María del Mar Noblejas-López, Cristina Nieto-Jimenez, Miguel Burgos, Mónica Gómez-Juárez, Juan Carlos Montero, Azucena Esparís-Ogando, Atanasio Pandiella, Eva M. Galán-Moya, Alberto Ocaña
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-9 (2019)
Abstract Background Triple negative breast cancer (TNBC) is an incurable disease where novel therapeutic strategies are needed. Proteolysis targeting chimeric (PROTAC) are novel compounds that promote protein degradation by binding to an ubiquitin li
Externí odkaz:
https://doaj.org/article/037decabfb344e37b370504e1a55b383
Autor:
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly desc
Externí odkaz:
https://doaj.org/article/a5c66f1d9aee408ab699697673fab805
Autor:
Juan Miguel Burgos, María Nazarena de Salvo, Gabriel Leonardo Cicuttin, María Susana Leguizamón
Publikováno v:
International Journal of Health Science. 3:2-6
Autor:
Liliana Cruz-Ausejo, David Villarreal-Zegarra, C. Mahony Reátegui-Rivera, Miguel Burgos, Ana L. Vilela-Estrada, Gabriel Castro, Héctor Collantes, Anthony Copez-Lonzoy
Publikováno v:
Revista de Psiquiatría y Salud Mental. 16:11-24