Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mignane B. Ka"'
Autor:
Laurent Gorvel, Julien Textoris, Romain Banchereau, Amira Ben Amara, Wiwit Tantibhedhyangkul, Kristin von Bargen, Mignane B Ka, Christian Capo, Eric Ghigo, Jean-Pierre Gorvel, Jean-Louis Mege
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99420 (2014)
Dendritic cells (DCs) orchestrate host defenses against microorganisms. In infectious diseases due to intracellular bacteria, the inefficiency of the immune system to eradicate microorganisms has been attributed to the hijacking of DC functions. In t
Externí odkaz:
https://doaj.org/article/f78e58b7e36a4afb8af35c3c38f1860a
Autor:
Mignane B Ka, Françoise Gondois-Rey, Christian Capo, Julien Textoris, Mathieu Million, Didier Raoult, Daniel Olive, Jean-Louis Mege
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107533 (2014)
Q fever endocarditis, a severe complication of Q fever, is associated with a defective immune response, the mechanisms of which are poorly understood. We hypothesized that Q fever immune deficiency is related to altered distribution and activation of
Externí odkaz:
https://doaj.org/article/57ceb99cdf13475394dcefb669843365
Autor:
Jiajie Hou, Alan J. Korman, Xian-Yang Li, Joe-Marc Chauvin, Diwakar Davar, Ornella Pagliano, Mark J. Smyth, John M. Kirkwood, Mignane B. Ka, Richelle DeBlasio, Quanquan Ding, Robert J. Johnston, Hassane M. Zarour, Cindy Sanders, Soldano Ferrone, Carmine Menna
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(20)
Purpose: Natural killer (NK) cells play a critical role in tumor immunosurveillance. Multiple activating and inhibitory receptors (IR) regulate NK-cell–mediated tumor control. The IR T-cell immunoglobulin and ITIM domain (TIGIT) and its counter-rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe51fefb43ee7971add608afe9144cf
https://pubmed.ncbi.nlm.nih.gov/32817077
https://pubmed.ncbi.nlm.nih.gov/32817077
Autor:
Ana C. Anderson, John M. Kirkwood, Alan J. Korman, Diwakar Davar, Hassane M. Zarour, Carmine Menna, Mignane B. Ka, Ornella Pagliano, Vijay K. Kuchroo, Joe-Marc Chauvin, Julien Foucade
Publikováno v:
Cancer Research. 80:IA02-IA02
Multiple mechanisms of melanoma-induced immune escape contribute to the failure of T-cell responses to control tumor growth in humans. Many inhibitory pathways play a critical role in impeding T-cell responses to tumor antigens (TAs), including PD-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e415da5cdd5a972c219dff61d5172142
https://doi.org/10.1158/1538-7445.mel2019-ia02
https://doi.org/10.1158/1538-7445.mel2019-ia02
Autor:
Apurva Pandey, Mignane B. Ka, Carmine Menna, Priscilla F. McAuliffe, Adam Brufsky, Joe Marc Chauvin, Hassane M. Zarour, Ornella Pagliano
Publikováno v:
Cancer Research. 80:P5-04
Background: Triple negative breast cancer is aggressive and has poor prognosis. Tumor infiltrating lymphocytes (TILs) have a prognostic value in triple negative breast cancer. Increased TILs are associated with better disease-free survival and overal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e7cf97a80fb5bb7f6a519f10aca725
https://doi.org/10.1158/1538-7445.sabcs19-p5-04-28
https://doi.org/10.1158/1538-7445.sabcs19-p5-04-28
Autor:
Hussein Abdul-Hassan Tawbi, Cindy Sander, Amir A. Borhani, Blanca Hornet Moreno, John M. Kirkwood, Hong Wang, Mignane B. Ka, Amy Rose, Ornella Pagliano, Ahmad A. Tarhini, Qing Zhao, Julien Fourcade, Nageatte Ibrahim, S. Ebbinghaus, Diwakar Davar, Arivarasan Karunamurthy, Joe Marc Chauvin, Hassane M. Zarour, Carmine Menna
Purpose Objective responses are reported in 34% to 37% of patients with programmed death-1 (PD-1)–naïve advanced melanoma treated with PD-1 inhibitors. Pre-existing CD8+ T-cell infiltrate and interferon (IFN) gene signature correlate with response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b964d318683b8fc04d59fc6e9ab6e1fb
https://europepmc.org/articles/PMC6286160/
https://europepmc.org/articles/PMC6286160/
Autor:
Alan J. Korman, Diwakar Davar, Cindy Sander, Mignane B. Ka, John M. Kirkwood, Julien Fourcade, Hassane M. Zarour, Hong Wang, Ornella Pagliano, Zhaojun Sun, Joe-Marc Chauvin, Sofiane Saada, Carmine Menna, Rada Amin
CD4+ Tregs impede T cell responses to tumors. They express multiple inhibitory receptors that support their suppressive functions, including T cell Ig and ITIM domain (TIGIT). In melanoma patients, we show that Tregs exhibit increased TIGIT expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b285657653ceffba41ce16464236057
https://europepmc.org/articles/PMC6124410/
https://europepmc.org/articles/PMC6124410/
Autor:
Mignane B, Ka, Soraya, Mezouar, Amira, Ben Amara, Didier, Raoult, Eric, Ghigo, Daniel, Olive, Jean-Louis, Mege
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Plasmacytoid dendritic cells (pDCs) play a major role in antiviral immunity via the production of type I interferons (IFNs). There is some evidence that pDCs interact with bacteria but it is not yet clear whether they are protective or contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::596ea4941a452de1820a89564449b31e
https://pubmed.ncbi.nlm.nih.gov/27446817
https://pubmed.ncbi.nlm.nih.gov/27446817
Autor:
Didier Raoult, Mignane B. Ka, Jean-Louis Mege, Daniel Olive, Eric Ghigo, Françoise Gondois-Rey
Publikováno v:
Pathogens and Disease. 73:1-3
Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8(+) T lymphocytes and CD56dim natural ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ea673432c8c975dc2c7c38610dbab0
https://doi.org/10.1093/femspd/ftu010
https://doi.org/10.1093/femspd/ftu010
Publikováno v:
Microbial pathogenesis. 80
Programmed death ligand-1 (PD-L1) is a co-signaling molecule that regulates T-cell responses in vivo. Its role in bacterial infections, including Q fever, a zoonosis due to Coxiella burnetii infection, is not well understood. We showed by flow cytome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35c21f69c4ac943461fa082df1fe31a
https://pubmed.ncbi.nlm.nih.gov/25680834
https://pubmed.ncbi.nlm.nih.gov/25680834