Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

Autor: Benvenuto, M, Angiolini, V, Focaccetti, C, Nardozi, D, Palumbo, C, Carrano, R, Rufini, A, Bei, R, Miele, Mt, Mancini, P, Barillari, G, Cirone, M, Ferretti, E, Tundo, Gr, Mutti, L, Masuelli, L

Publikováno v: Biology Direct. 18

Background Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low efficacy of current treatment options highlights the urge to identify more effective therapies aimed at improving MM patients’ survival. Bortezomib (Bor) is a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754f5e55ea7b4ea9e9abeba4b4be2ed0
https://doi.org/10.1186/s13062-023-00374-w

Late termination of pregnancy in case of congenital CMV infection: ethics, medicine and law.

Autor: Gulino M; Department of Clinical Science and Translational Medicine, University of Rome 'Tor Vergata', Rome, Italy., Miele MT; Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy., Marcuccilli F; Laboratory of Clinical Microbiology and Virology, University Hospital Tor Vergata, Rome, Italy., Cammarano A; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy., Montanari Vergallo G; Department of Anatomical, Histological, Medico-Legal and Orthopaedic Sciences, 'Sapienza' University of Rome, Rome, Italy.

Publikováno v: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2022 Dec; Vol. 35 (25), pp. 9786-9791. Date of Electronic Publication: 2022 Mar 25.

Differential Expression of Endogenous Retroviruses and Inflammatory Mediators in Female and Male Offspring in a Mouse Model of Maternal Immune Activation.

Autor: Cipriani C; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Tartaglione AM; Center for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità (ISS), 00161 Rome, Italy., Giudice M; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., D'Avorio E; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Petrone V; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Toschi N; Department of Biomedicine and Prevention, Tor Vergata University of Rome, 00133 Rome, Italy.; Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, MA 02115, USA., Chiarotti F; Center for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità (ISS), 00161 Rome, Italy., Miele MT; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Calamandrei G; Center for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità (ISS), 00161 Rome, Italy., Garaci E; University San Raffaele, 00166 Rome, Italy.; IRCCS San Raffaele Pisana, 00163 Rome, Italy., Matteucci C; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Sinibaldi-Vallebona P; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.; Institute of Translational Pharmacology, National Research Council, 00133 Rome, Italy., Ricceri L; Center for Behavioral Sciences and Mental Health, Istituto Superiore di Sanità (ISS), 00161 Rome, Italy., Balestrieri E; Department of Experimental Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 11; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 11.

Polyphenols affect the humoral response in cancer, infectious and allergic diseases and autoimmunity by modulating the activity of T H 1 and T H 2 cells.

Autor: Benvenuto M; Saint Camillus International University of Health and Medical Sciences, Via di Sant'Alessandro 8, 00131 Rome, Italy; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy., Focaccetti C; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy; Department of Human Science and Promotion of the Quality of Life, San Raffaele University Rome, Via di Val Cannuta 247, 00166 Rome, Italy., Ciuffa S; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy., Fazi S; Department of Experimental Medicine, University of Rome 'Sapienza', Viale Regina Elena 324, 00161 Rome, Italy., Bei A; Medical School, University of Rome 'Tor Vergata', 00133 Rome, Italy., Miele MT; Department of Experimental Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy., Albonici L; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy., Cifaldi L; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy; Academic Department of Pediatrics (DPUO), Ospedale Pediatrico Bambino Gesù, IRCCS, Piazza Sant'Onofrio 4, 00165 Rome, Italy., Masuelli L; Department of Experimental Medicine, University of Rome 'Sapienza', Viale Regina Elena 324, 00161 Rome, Italy., Bei R; Department of Clinical Sciences and Translational Medicine, University of Rome 'Tor Vergata', Via Montpellier 1, 00133 Rome, Italy. Electronic address: bei@med.uniroma2.it.

Publikováno v: Current opinion in pharmacology [Curr Opin Pharmacol] 2021 Oct; Vol. 60, pp. 315-330. Date of Electronic Publication: 2021 Sep 11.

Thymosin Alpha 1 Mitigates Cytokine Storm in Blood Cells From Coronavirus Disease 2019 Patients.

Autor: Matteucci C; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Minutolo A; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Balestrieri E; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Petrone V; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Fanelli M; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Malagnino V; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Infectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy., Ianetta M; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Infectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy., Giovinazzo A; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Barreca F; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Infectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy., Di Cesare S; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Unit of Immune and Infectious Diseases, Academic Department of Pediatrics, Bambino Gesù Childrens' Hospital-Scientific Institute for Research and Healthcare (IRCCS), Rome, Italy., De Marco P; Respiratory Medicine Unit, University Hospital Policlinico Tor Vergata, Rome, Italy., Miele MT; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Toschi N; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.; Athinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, Boston, Massachusetts, USA., Mastino A; Institute of Translational Pharmacology, National Research Council, Rome, Italy.; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy., Sinibaldi Vallebona P; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.; Institute of Translational Pharmacology, National Research Council, Rome, Italy., Bernardini S; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Rogliani P; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.; Respiratory Medicine Unit, University Hospital Policlinico Tor Vergata, Rome, Italy., Sarmati L; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Infectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy., Andreoni M; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.; Infectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy., Grelli S; Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.; Virology Unit, Policlinic of Tor Vergata, Rome, Italy., Garaci E; University San Raffaele, Rome, Italy.; IRCCS San Raffaele Pisana, Rome, Italy.

Publikováno v: Open forum infectious diseases [Open Forum Infect Dis] 2020 Dec 05; Vol. 8 (1), pp. ofaa588. Date of Electronic Publication: 2020 Dec 05 (Print Publication: 2021).