Výsledky vyhledávání - "Mieke W. J. C. Jansen"

Diagnostic tool for the identification of MLL rearrangements including unknown partner genes

Autor: Oskar A. Haas, Theo Dingermann, Claudia Schoch, Claus Meyer, Sieglinde Angermueller, Jacques J.M. van Dongen, Rolf Marschalek, Martin Reichel, Susanne Schnittger, Sabine Strehl, Rob Pieters, Bjoern Schneider, Mieke W. J. C. Jansen, Thomas Klingebiel

Publikováno v: Proceedings of the National Academy of Sciences of the U.S.A., 102, 449-454. National Academy of Sciences

Approximately 50 different chromosomal translocations of the human MLL gene are currently known and associated with high-risk acute leukemia. The large number of different MLL translocation partner genes makes a precise diagnosis a demanding task. Af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a61a1caea159eab35cbf3c8208110a6
https://doi.org/10.1073/pnas.0406994102

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Preeclampsia and its interaction with common variants in thrombophilia genes

Autor: Frans M. Helmerhorst, E. T. M. Hille, S. Buitendijk, Mieke W. J. C. Jansen, Juriy W. Wladimiroff, C.J.M. de Groot, R M Bertina, M.P.M. de Maat, Kitty W.M. Bloemenkamp, Hans L. Vos

Publikováno v: Journal of Thrombosis and Haemostatis, 9, 2, 1588-1593
Journal of thrombosis and haemostasis, 2(9), 1588-1593. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 2, 1588-1593. Wiley-Blackwell Publishing Ltd

Recently, it has been proposed that abnormalities in coagulation and fibrinolysis contribute to the development of preeclampsia by increasing the thrombotic tendency. This hypothesis was tested in women who have had preeclampsia (cases) compared with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36dc5ac4ddc54f8ce035e64c4bc13f44
https://doi.org/10.1111/j.1538-7836.2004.00861.x

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Acute lymphoblastic leukemia followed by a clonally-unrelated EBV-positive non-Hodgkin lymphoma and a clonally-related myelomonocytic leukenia cutis

Autor: Gerard A.M. de Vaan, José Bogman, Jacques J.M. van Dongen, Tomasz Szczepański, Auke Beishuizen, Elisabeth R. van Wering, Mieke W. J. C. Jansen

Publikováno v: Pediatric Blood & Cancer, 42, 343-349. Wiley-Liss Inc.

Background Complicating malignant hematopoietic proliferations might severely hamper the course of acute lymphoblastic leukemia (ALL) in patients with an otherwise good prognosis. It is important to distinguish whether such neoplastic proliferations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac7facdccb4fc7ad1788e988560cf0b
https://doi.org/10.1002/pbc.10466

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C825T polymorphism in the human G protein 3 subunit gene and preeclampsia; a case control study

Autor: Kitty W. M. Bloemenkamp, Frans M. Helmerhorst, Rogier M. Bertina, Christianne J.M. de Groot, Mieke W. J. C. Jansen, Juriy W. Wladimiroff, Hans L. Vos

Publikováno v: Hypertension in Pregnancy, 23, 1-8. Informa Healthcare

OBJECTIVE Recently, a polymorphism of the gene encoding for the G protein beta3-subunit (GNB3) has been described. The T allele of this polymorphism (825T) is associated with endothelium dysfunction. Endothelium dysfunction has been described in wome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e87a1ac14cbe134cd9b5d785d88a17
https://doi.org/10.1081/PRG-120028482

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How useful is thein vitro expansion of fetal CD34+ progenitor cells from maternal blood samples for diagnostic purposes?

Autor: Karin Korver-Hakkennes, Rob E. Ploemacher, Helen Brandenburg, Mieke W. J. C. Jansen, Juriy W. Wladimiroff, Hajo I. J. Wildschut, Dik van Leenen

Publikováno v: Prenatal Diagnosis. 20:725-731

Fetal cells present in the maternal circulation are a potential source of fetal DNA that can be used for the development of a prenatal diagnostic test. Since their numbers are very low, amplification of fetal cells has been discussed for a long time.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06354bb3a0b25c319b6119df961d08b0
https://doi.org/10.1002/1097-0223(200009)20:9<725::aid-pd913>3.0.co

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The use ofin vitro expanded erythroid cells in a model system for the isolation of fetal cells from maternal blood

Autor: Juriy W. Wladimiroff, Helen Brandenburg, Hartmut Beug, Peter A. In 't Veld, Mieke W. J. C. Jansen, Hajo I. J. Wildschut, Marieke von Lindern

Publikováno v: Prenatal Diagnosis. 19:323-329

The development of a non-invasive prenatal diagnostic test using fetal nucleated red blood cells (NRBCs) isolated from the maternal circulation is hampered by the low frequency of these cells in maternal blood, requiring extensive enrichment procedur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a14011939e66acf66e223852d974b45f
https://doi.org/10.1002/(sici)1097-0223(199904)19:4<323::aid-pd534>3.0.co

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The effect of chorionic villus sampling on the number of fetal cells isolated from maternal blood and on maternal serum alpha-fetoprotein levels

Autor: Juriy W. Wladimiroff, Peter A. In 't Veld, Anton C.M. Martens, Adriana M. Hagenaars, Mieke W. J. C. Jansen, Helen Brandenburg, Hajo I. J. Wildschut

Publikováno v: Prenatal Diagnosis. 17:953-959

Fetal cells are present in the circulation of pregnant women and can be isolated using density gradient centrifugation and magnetic cell sorting. In the present study, maternal cell preparations were depleted for CD45- and CD14-positive cells and enr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61bd5012223ad27688e138c61d5a5e51
https://doi.org/10.1002/(sici)1097-0223(199710)17:10<953::aid-pd182>3.0.co

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Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4.MLL fusion allele

Autor: Rolf Marschalek, Theodor Dingermann, Luca Lo Nigro, Thomas Burmeister, Mieke W. J. C. Jansen, Eric Delabesse, Thomas Klingebiel, Eric Kowarz, Christian Meyer

Publikováno v: Leukemia. 21(6)

The human mixed lineage leukemia (MLL) gene is frequently involved in genetic rearrangements with more than 55 different translocation partner genes, all associated with acute leukemia. Reciprocal chromosomal translocations generate two MLL fusion al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e73250d0f9b120fdeeb306766fe1050
https://pubmed.ncbi.nlm.nih.gov/17410185

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Significantly higher number of fetal cells in the maternal circulation of women with pre-eclampsia

Autor: Juriy W. Wladimiroff, Mieke W. J. C. Jansen, Dik van Leenen, Peter A. In 't Veld, Karin Korver-Hakkennes, Christianne J.M. de Groot, Willy Visser

Publikováno v: Prenatal Diagnosis, 21, 1022-1026. John Wiley & Sons Ltd.

Although the pathophysiology of pre-eclampsia is unknown, several studies have indicated that abnormal placentation early in pregnancy might play a key role. It has recently been suggested that this abnormal placentation may result in transfusion of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5d656e79f7d6245a5fad7f984241d5
https://pubmed.ncbi.nlm.nih.gov/11746158

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Interleukin 10-2849AA genotype protects against pre-eclampsia

Autor: Twj Huizinga, Joris J. M. Schonkeren, C.J.M. de Groot, Frans M. Helmerhorst, Rogier M. Bertina, Mieke W. J. C. Jansen

Publikováno v: Genes and Immunity, 5(4), 313-314. Nature Publishing Group

Recently, it has been described that human fertility is associated with the interleukin 10 (IL10) -2849 AA genotype. Pre-eclampsia is the most common pregnancy-specific complication. In the pathogenesis of pre-eclampsia, IL10 may affect maternal intr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ec2a1e208291fa39ff92e69d6be281
https://doi.org/10.1038/sj.gene.6364092

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