Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mieke Vanbrabant"'
Autor:
Christian Frezza, Luca Scorrano, Joél Smet, Rudy Van Coster, Wilhelm Mandemakers, Vanessa A. Morais, Anne Roethig, Wolfgang Wurst, An Snellinx, Dominik Haddad, Bart De Strooper, Daniela Vogt-Weisenhorn, Patrik Verstreken, Mieke Vanbrabant
Publikováno v:
EMBO Molecular Medicine. 1:99-111
Mutations of the mitochondrial PTEN (phosphatase and tensin homologue)-induced kinase1 (PINK1) are important causes of recessive Parkinson disease (PD). Studies on loss of function and overexpression implicate PINK1 in apoptosis, abnormal mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f060bab73c0ba9c03c35209e27c238fe
https://doi.org/10.1002/emmm.200900006
https://doi.org/10.1002/emmm.200900006
Autor:
Bart De Strooper, Kurt Spittaels, Mieke Vanbrabant, Dirk Pollet, Veerle Baekelandt, André Delacourte, Mik Staes, Frea Coun, Adrian Cohen, Amantha Thathiah, Marcel Hoffmann, Katrien Horré, David F. Fischer, Pascal Gerard Merchiers
Publikováno v:
Science. 323:946-951
Deposition of the amyloid-β peptide is a pathological hallmark of Alzheimer's disease. A high-throughput functional genomics screen identified G protein–coupled receptor 3 (GPR3), a constitutively active orphan G protein–coupled receptor, as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b3533dc2b178e739442da10106a857
https://doi.org/10.1126/science.1160649
https://doi.org/10.1126/science.1160649
Autor:
Patrick Van Gelder, Dieter Hartmann, Inna Kuperstein, Elke Maes, Frederic Rousseau, Wim Jonckheere, Mieke Vanbrabant, Joost Schymkowitz, Rudi D'Hooge, Hannah Wilkinson, Bart De Strooper, Ivo C. Martins
Publikováno v:
The EMBO Journal
Although soluble oligomeric and protofibrillar assemblies of Abeta-amyloid peptide cause synaptotoxicity and potentially contribute to Alzheimer's disease (AD), the role of mature Abeta-fibrils in the amyloid plaques remains controversial. A widely h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14211f081b81301adc3baf32d5b10748
https://doi.org/10.1038/sj.emboj.7601953
https://doi.org/10.1038/sj.emboj.7601953
Autor:
Joost Schymkowitz, Bart De Strooper, Ivo C. Martins, Frederic Rousseau, Rudi D'Hooge, Elke Maes, Mieke Vanbrabant, Inna Kuperstein, Hannah Wilkinson
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ec71154bddadc9bbceca9d56a2c3aa
https://doi.org/10.1016/j.jalz.2008.05.316
https://doi.org/10.1016/j.jalz.2008.05.316