Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mieke Trekels"'
Autor:
Vanessa Dubois, Jacques Young, Mieke Trekels, Annelien Verfaillie, Christine Helsen, Marc De Maeyer, Frank Claessens, Renée Vancraenenbroeck
Publikováno v:
Molecular and cellular biology. 32(15)
DNA binding as well as ligand binding by nuclear receptors has been studied extensively. Both binding functions are attributed to isolated domains of which the structure is known. The crystal structure of a complete receptor in complex with its ligan
Autor:
Mieke Trekels, Tom Venken, Wim M. De Borggraeve, Rani Alphonsa Jose, Aline Vandenbulcke, Marc De Maeyer, Katleen Broos, Jonas Demeulemeester, Nele Vandeputte, Hans Deckmyn, Brecht Egle
Publikováno v:
The Journal of biological chemistry. 287(12)
The von Willebrand factor (VWF) A1-glycoprotein (GP) Ibα interaction is of major importance during thrombosis mainly at sites of high shear stress. Inhibitors of this interaction prevent platelet-dependent thrombus formation in vivo, without major b
Autor:
Mieke Trekels, Eveline Lescrinier, Hugo Ceulemans, Peter Vangheluwe, Luc Raeymaekers, Marc De Maeyer, Frank Wuytack, Ilse Vandecaetsbeek
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(44)
Sarco(endo)plasmic reticulum Ca 2+ ATPase (SERCA) Ca 2+ transporters pump cytosolic Ca 2+ into the endoplasmic reticulum, maintaining a Ca 2+ gradient that controls vital cell functions ranging from proliferation to death. To meet the physiological d