Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mieke Roosen"'
Publikováno v:
Acta neuropathologica. 143(4)
Pediatric neoplasms in the central nervous system (CNS) are the leading cause of cancer-related deaths in children. Recent developments in molecular analyses have greatly contributed to a more accurate diagnosis and risk stratification of CNS tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b618871ce8eb45dda002ec93586242
https://pubmed.ncbi.nlm.nih.gov/35169893
https://pubmed.ncbi.nlm.nih.gov/35169893
Autor:
Ziva Pogacar, Kelvin Groot, Fleur Jochems, Matheus Dos Santos Dias, Ben Morris, Mieke Roosen, Leyma Wardak, Giulia De Conti, Arno Velds, Cor Lieftink, Roderick L. Beijersbergen, René Bernards, Rodrigo Leite de Oliveira
Discovering biomarkers of drug response and finding powerful drug combinations can support the reuse of previously abandoned cancer drugs in the clinic. Indisulam is an abandoned drug that acts as a molecular glue, inducing degradation of splicing fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07406f3dd0e5b275179fb50e99060e7b
https://doi.org/10.1101/2021.12.20.473451
https://doi.org/10.1101/2021.12.20.473451
Autor:
Onno Kranenburg, Anneta Brousali, Trudy N. Jonges, Evelien de Jongh, Hans Clevers, Mieke Roosen, Jeroen Korving, Jasper Mullenders, Richard P. Meijer, Harry Begthel, Jan P. A. Blom
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4567-4574. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4567
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4567
Bladder cancer is a common malignancy that has a relatively poor outcome. Lack of culture models for the bladder epithelium (urothelium) hampers the development of new therapeutics. Here we present a long-term culture system of the normal mouse uroth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6d813f0879c4b05d6aa74bf1a0c6bf
https://doi.org/10.1073/pnas.1803595116
https://doi.org/10.1073/pnas.1803595116
Publikováno v:
Neuro-Oncology. 24:i40-i40
Ependymomas (EPN) are neuroepithelial tumors of the central nervous system occurring both in adults and children. DNA methylation profiling has identified ten distinct molecular groups. In the supratentorial (ST) compartment, ZFTA-fusion positive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a505c2cd0c80265c47410cf50103c59
https://doi.org/10.1093/neuonc/noac079.147
https://doi.org/10.1093/neuonc/noac079.147
Autor:
Jens Bunt, Mieke Roosen, Phylicia Stathi, Panagiotis Polychronopoulos, Zelda Odé, Joris Maas, Marcel Kool
Publikováno v:
Neuro-Oncology. 24:i51-i51
Over the last decade, molecular characterization has resulted in many tumors previously classified as central nervous system primitive neuroectodermal tumors (CNS-PNETs) now being classified into their own distinct tumor types. These novel types are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006cb0bb5afd4ca84743b9d662403b9a
https://doi.org/10.1093/neuonc/noac079.187
https://doi.org/10.1093/neuonc/noac079.187
Autor:
Zelda Odé, Joris Maas, Mieke Roosen, Phylicia Stathi, Aniello Federico, Norman Mack, Benjamin Schwalm, Jens Bunt, Marcel Kool
Publikováno v:
Neuro-Oncology. 24:i118-i118
Four main medulloblastoma (MB) molecular subgroups are known, including the sonic hedgehog (SHH) subgroup, which represents ~25% of MB cases. The 5-year overall survival of SHH-MB is ~80%. However, survival between patients is highly diverse and depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f523bc96a7a27bb2da2dbec0b850a288
https://doi.org/10.1093/neuonc/noac079.426
https://doi.org/10.1093/neuonc/noac079.426
Autor:
Ziva Pogacar, Kelvin Groot, Fleur Jochems, Matheus Dos Santos Dias, Antonio Mulero-Sánchez, Ben Morris, Mieke Roosen, Leyma Wardak, Giulia De Conti, Arno Velds, Cor Lieftink, Bram Thijssen, Roderick L Beijersbergen, René Bernards, Rodrigo Leite de Oliveira
Publikováno v:
Pogacar, Z, Groot, K, Jochems, F, Dos Santos Dias, M, Mulero-Sánchez, A, Morris, B, Roosen, M, Wardak, L, de Conti, G, Velds, A, Lieftink, C, Thijssen, B, Beijersbergen, R L, Bernards, R & Leite de Oliveira, R 2022, ' Genetic and compound screens uncover factors modulating cancer cell response to indisulam ', Life Science Alliance, vol. 5, no. 9, e202101348 . https://doi.org/10.26508/lsa.202101348
Life Science Alliance, 5(9):e202101348. Rockefeller University Press
Life Science Alliance, 5(9):e202101348. Rockefeller University Press
Discovering biomarkers of drug response and finding powerful drug combinations can support the reuse of previously abandoned cancer drugs in the clinic. Indisulam is an abandoned drug that acts as a molecular glue, inducing degradation of splicing fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cdc473b5591bee070a296d2e74ece6
https://doi.org/10.26508/lsa.202101348
https://doi.org/10.26508/lsa.202101348
Publikováno v:
Neuro-Oncology. 23:i35-i36
Background One of the bottlenecks in basic and translational research on pediatric brain tumors, is the lack of suitable and representative preclinical models to study tumor biology and drug sensitivity. Over the last decades, extensive molecular cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03d58db1559cbaa3ab1179064a850d16
https://doi.org/10.1093/neuonc/noab090.143
https://doi.org/10.1093/neuonc/noab090.143
Autor:
Kendra K. Maass, Mieke Roosen, Tatjana Wedig, Kristian W. Pajtler, Stefan M. Pfister, Julia Benzel, Britta Statz, Torsten Mueller, Mathias Kalxdorf, Jeroen Krijgsveld
Publikováno v:
Neuro-Oncology
Ependymal tumors (EPNs) account for ~10% of all pediatric brain tumors. Supratentorial EPN characterized by RELA fusions (ST-EPN-RELA) and posterior fossa EPN group A (PF-EPN-A) form the two most frequent molecular groups, both of which are associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e006982d13753ae6aa0f7ca9cddb942
http://europepmc.org/articles/PMC7715232
http://europepmc.org/articles/PMC7715232
Autor:
Anneta Brousali, Evelien de Jongh, Trudy N. Jonges, Mieke Roosen, Jasper Mullenders, Hans Clevers, Richard P. Meijer
Publikováno v:
Urologic Oncology: Seminars and Original Investigations, 35(10), 616. Elsevier Inc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bf7560bbeb3553fa4d9d6044c215cb
https://hdl.handle.net/1874/357674
https://hdl.handle.net/1874/357674