Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mieke Roefs"'
Autor:
Maarten van Lohuizen, Stijn de Vries, J. Deschamps, Bernard A.J. Roelen, Silvia Marino, Mieke Roefs, Jan Willem Voncken, E. Verhoeven
Publikováno v:
Proceedings of the National Academy of Sciences. 100:2468-2473
The highly homologous Rnf2 (Ring1b) and Ring1 (Ring1a) proteins were identified as in vivo interactors of the Polycomb Group (PcG) protein Bmi1. Functional ablation of Rnf2 results in gastrulation arrest, in contrast to relatively mild phenotypes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a641ad254d310bef3d3d1a14c090e54
https://doi.org/10.1073/pnas.0434312100
https://doi.org/10.1073/pnas.0434312100
Autor:
Alrik P. Los, Mieke Roefs, Nullin Divecha, Clive D'Santos, Jonathan R. Halstead, Andrew J. Bannister
Publikováno v:
Current Biology. 12:582-587
Inositide signaling at the plasma membrane has been implicated in the regulation of numerous cellular processes including cytoskeletal dynamics, vesicle trafficking [1], and gene transcription [2]. Studies have also shown that a distinct inositide pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7ae7b8efde4b2c31b4c6abea0649c7
https://doi.org/10.1016/s0960-9822(02)00769-8
https://doi.org/10.1016/s0960-9822(02)00769-8
Autor:
Mieke Roefs, Michael J.O. Wakelam, Nullin Divecha, Sabine d'Andrea, Kahlid M. Saqib, Mar Fernandez‐Borga, L. C. J. M. Oomen, Jonathan R. Halstead, Clive D'Santos
Publikováno v:
The EMBO Journal. 19:5440-5449
Phosphoinositides are localized in various intracellular compartments and can regulate a number of intracellular functions, such as cytoskeletal dynamics and membrane trafficking. Phospholipase Ds (PLDs) are regulated enzymes that hydrolyse phosphati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81ee38c6b125d017d2f8ce9ffcc42a8
https://doi.org/10.1093/emboj/19.20.5440
https://doi.org/10.1093/emboj/19.20.5440
Publikováno v:
Cellular and Molecular Life Sciences. 57:379-393
It is now clear that phosphoinositides, which play a major role in the regulation of a variety of cellular processes in the cytoplasm, are found within the nucleus. Their role in this subcellular compartment is still contentious: however, data has su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99279db0f99a6b4f4f9922c97e41b90f
https://doi.org/10.1007/pl00000700
https://doi.org/10.1007/pl00000700
Autor:
Sabine d'Andrea, Nullin Divecha, Jonathan R. Halstead, Chris D. Ellson, Clive D'Santos, Mieke Roefs, Ching Shih Chen
Publikováno v:
Current Biology. (6):386-395
Background: Phosphatidylinositol-3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] is a key second messenger found ubiquitously in higher eukaryotic cells. The activation of Class I phosphoinositide 3-kinases and the subsequent production of PtdIns(3,4,5)P 3 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f159112fcf671dcbaba04418fb11739