Výsledky vyhledávání - "Mieke R. van Bockstal"

Akademický článek

Systematic assessment of HER2 status in ductal carcinoma in situ of the breast: a perspective on the potential clinical relevance

Autor: Mieke R. Van Bockstal, Jelle Wesseling, Ester H. Lips, Marjolein Smidt, Christine Galant, Carolien H. M. van Deurzen

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)

Abstract In many countries, hormone receptor status assessment of ductal carcinoma in situ (DCIS) is routinely performed, as hormone receptor-positive DCIS patients are eligible for adjuvant anti-hormonal treatment, aiming to reduce the ipsilateral a

Externí odkaz: https://doaj.org/article/a62aff1bce4848c3bace74b6a84df2d9

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Akademický článek

Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers

Autor: Françoise Derouane, Manon Desgres, Camilla Moroni, Jérôme Ambroise, Martine Berlière, Mieke R. Van Bockstal, Christine Galant, Cédric van Marcke, Marianela Vara-Messler, Stefan J. Hutten, Jos Jonkers, Larissa Mourao, Colinda L. G. J. Scheele, Francois P. Duhoux, Cyril Corbet

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-19 (2024)

Abstract Background Neoadjuvant chemotherapy (NAC) is the standard of care for patients with early-stage triple negative breast cancers (TNBC). However, more than half of TNBC patients do not achieve a pathological complete response (pCR) after NAC,

Externí odkaz: https://doaj.org/article/cbcb7ddcc69b4cbbb96f42be1600415c

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Akademický článek

Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification

Autor: Mieke R. Van Bockstal, Marie Colombe Agahozo, Ronald van Marion, Peggy N. Atmodimedjo, Hein F. B. M. Sleddens, Winand N. M. Dinjens, Lindy L. Visser, Esther H. Lips, Jelle Wesseling, Carolien H. M. van Deurzen

Publikováno v: Molecular Oncology, Vol 14, Iss 4, Pp 671-685 (2020)

Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of

Externí odkaz: https://doaj.org/article/bab2d6a1b653450da771b3f429430417

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Interobserver Variation in the Assessment of Immunohistochemistry Expression Levels in HER2-Negative Breast Cancer: Can We Improve the Identification of Low Levels of HER2 Expression by Adjusting the Criteria? An International Interobserver Study

Autor: Ximena Baez-Navarro, Mieke R. van Bockstal, Diënna Nawawi, Glenn Broeckx, Cecile Colpaert, Shusma C. Doebar, Marieke C.H. Hogenes, Esther Koop, Kathleen Lambein, Dieter J.E. Peeters, Renata H.J.A. Sinke, Johannes Bastiaan van Brakel, José van der Starre-Gaal, Bert van der Vegt, Koen van de Vijver, Celien P.H. Vreuls, Willem Vreuls, Pieter J. Westenend, Carolien H.M. van Deurzen

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 36(1):100009. Nature Publishing Group
Modern pathology

The classification of human epidermal growth factor receptor 2 (HER2) expression is optimized to detect HER2-amplified breast cancer (BC). However, novel HER2-targeting agents are also effective for BCs with low levels of HER2. This raises the questi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ce9b664588b0e92337fad300871070
https://pure.eur.nl/en/publications/018e2521-96dd-4830-a731-e34e7c786351

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Breast-implant Related Silicone Lymphadenopathy: Asteroid Bodies do not Always Equal Sarcoidosis!

Autor: Mieke R. Van Bockstal, Louis Libbrecht, Angélique Dubail, Martine Berlière, Christine Galant

Publikováno v: International journal of surgical pathology.

Silicone breast implants are frequently used for breast augmentation for cosmetic purposes, as well as for breast reconstruction after prophylactic or therapeutic mastectomy. Silicone lymphadenopathy is a well-known complication of silicone breast im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3239ae12cc9ada33316eaefabc83ca61
https://pubmed.ncbi.nlm.nih.gov/36314437

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HER2-Low Breast Cancer: Incidence, Clinicopathologic Features, and Survival Outcomes From Real-World Data of a Large Nationwide Cohort

Autor: Ximena Baez-Navarro, Mieke R. van Bockstal, Eleni-Rosalina Andrinopoulou, Carolien H.M. van Deurzen

Publikováno v: Modern Pathology. 36:100087

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7512924e13382f16d47590f00ebe8be3
https://doi.org/10.1016/j.modpat.2022.100087

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Morphological intratumor heterogeneity in ductal carcinoma in situ of the breast

Autor: François Duhoux, Latifa Fellah, Claudia Maria Stanciu-Pop, Christine Galant, Mieke R. Van Bockstal, Marie-Cécile Nollevaux, Martine Berlière

Publikováno v: Virchows Archiv, Vol. 479, no. 1, p. 33-43 (2021)

Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous disease in terms of morphological characteristics, protein expression profiles, genetic abnormalities, and potential for progression. Molecular heterogeneity has been extensively studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f9708cf2126b1df1a4a8f14904561a
https://doi.org/10.1007/s00428-021-03040-6

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Interobserver variability in the assessment of stromal tumor-infiltrating lymphocytes (sTILs) in triple-negative invasive breast carcinoma influences the association with pathological complete response: the IVITA study

Publikováno v: MODERN PATHOLOGY
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Modern Pathology, 34, 2130-2140
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Modern pathology
Modern pathology, Vol. 34, no.12, p. 2130-2140 (2021)
Modern Pathology, 34(12), 2130-2140. Nature Publishing Group
Modern Pathology, 34, 12, pp. 2130-2140

Contains fulltext : 245198.pdf (Publisher’s version ) (Closed access) High stromal tumor-infiltrating lymphocytes (sTILs) in triple-negative breast cancer (TNBC) are associated with pathological complete response (pCR) after neoadjuvant chemotherap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d78a58fa670cf8130033afa1c817b9
https://doi.org/10.1038/s41379-021-00865-z

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The Liver in COVID-19-Related Death: Protagonist or Innocent Bystander?

Autor: Mieke R. Van Bockstal, Pamela Baldin, Jessica Vanhaebost, Yves Horsmans, Gregory Schmit, Julie Lelotte

Publikováno v: Pathobiology, Vol. 88, no. 1, p. 88-94 (2021)
Pathobiology

Introduction: The coronavirus disease 2019 (COVID-19) infection, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), involves several organs through participation of angiotensin-conversion enzyme 2 (ACE2) receptors. The presence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d431db87ec4ecafd4c4fe50f6e76d25a
https://doi.org/10.1159/000512008

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