Výsledky vyhledávání - "Mieke Nickien"

Comparison between in vitro and in vivo cartilage overloading studies based on a systematic literature review

Autor: Ashley Heuijerjans, Mieke Nickien, Corrinus C. van Donkelaar, Keita Ito

Publikováno v: Journal of Orthopaedic Research®. 36:2076-2086

Methodological differences between in vitro and in vivo studies on cartilage overloading complicate the comparison of outcomes. The rationale of the current review was to (i) identify consistencies and inconsistencies between in vitro and in vivo stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de0cdaa360003f8a8a9361abb08a7842
https://doi.org/10.1002/jor.23910

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How a radial focal incision influences the internal shear distribution in articular cartilage with respect to its zonally differentiated microanatomy

Autor: Ashvin Thambyah, Mieke Nickien, Neil D. Broom

Publikováno v: Journal of Anatomy. 227:315-324

Articular surface fibrillation and the loss of both transverse interconnectivity and zonal differentiation are indicators of articular cartilage (AC) degeneration. However, exactly how these structural features affect the load-redistributing properti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a501d265dec3a6025f7a4688ed173db
https://doi.org/10.1111/joa.12350

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How a decreased fibrillar interconnectivity influences stiffness and swelling properties during early cartilage degeneration

Autor: Neil D. Broom, Ashvin Thambyah, Mieke Nickien

Publikováno v: Journal of the Mechanical Behavior of Biomedical Materials, 75, 390-398. Elsevier

Objective The functional coupling between the fibrillar network and the high-swelling proteoglycans largely determines the mechanical properties of the articular cartilage matrix. The objective of this new study was to show specifically how changes i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cecbaa8106d77e8d548bb8e40893e5b
https://research.tue.nl/nl/publications/957288ed-2742-4ece-84c2-4890968f0b87

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The influence of early osteoarthritic collagen network de-structuring in articular cartilage on the tissue stiffness and swelling properties

Autor: Neil D. Broom, Mieke Nickien, Ashvin Thambyah

Publikováno v: Osteoarthritis and Cartilage. 24:S374-S375

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1d45f9ae874eb6b24ff4676b0c7edf
https://doi.org/10.1016/j.joca.2016.01.668

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How changes in fibril-level organization correlate with the macrolevel behavior of articular cartilage

Autor: Ashvin Thambyah, Neil D. Broom, Mieke Nickien

Publikováno v: Wiley interdisciplinary reviews. Systems biology and medicine. 5(4)

The primary structural components of articular cartilage are the zonally differentiated interconnected network of collagen fibrils and proteoglycans, the latter having the potential to bind large amounts of water. Both components exist in a coupled r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27a4cb3bd0dd4ca4727a95303ae7eb9
https://pubmed.ncbi.nlm.nih.gov/23554314

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OS4-5 Mechanical and structural changes in the cartilage-bone system as a function of degeneration : New insight into the mechanobiology of osteoarthritis(OS4: Advanced Clinical Joint Biomechanics)

Autor: Rebekah Kim, Emily Hargrave-Thomas, Ashvin Thambyah, Neil D. Broom, Mieke Nickien

Publikováno v: The Proceedings of the Asian Pacific Conference on Biomechanics : emerging science and technology in biomechanics. :91

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17b0be846cd6b9b34f56fd884b5c65c4
https://doi.org/10.1299/jsmeapbio.2015.8.91

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