Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Mieke Gouwy"'
Autor:
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical application
Externí odkaz:
https://doaj.org/article/a3beb009fdca434c94d95233677ef312
Autor:
Luna Dillemans, Karen Yu, Alexandra De Zutter, Sam Noppen, Mieke Gouwy, Nele Berghmans, Lisa Verhallen, Mirre De Bondt, Lotte Vanbrabant, Stef Brusselmans, Erik Martens, Dominique Schols, Patrick Verschueren, Mette M. Rosenkilde, Pedro Elias Marques, Sofie Struyf, Paul Proost
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Interferon-γ-inducible protein of 10 kDa (IP-10/CXCL10) is a dual-function CXC chemokine that coordinates chemotaxis of activated T cells and natural killer (NK) cells via interaction with its G protein-coupled receptor (GPCR), C
Externí odkaz:
https://doaj.org/article/632073f48a4041208b11f2b4ff94603b
Autor:
Frederik Staels, Leoni Bücken, Leana De Vuyst, Mathijs Willemsen, Erika Van Nieuwenhove, Margaux Gerbaux, Julika Neumann, Vanshika Malviya, Lize Van Meerbeeck, Jeason Haughton, Laura Seldeslachts, Mieke Gouwy, Kimberly Martinod, Greetje Vande Velde, Paul Proost, Lidia Yshii, Susan Schlenner, Rik Schrijvers, Adrian Liston, Stephanie Humblet-Baron
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recently, OTULIN haploinsufficiency was linked to enhanced susceptibility to Staphylococcus aureus infections accompanied by local necrosis and systemic inflammation. The pathogenesis observed in haploinsufficient patients differs from the hyperinfla
Externí odkaz:
https://doaj.org/article/5abaa29f9c754698bb267d4fe1544942
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
BCR::ABL1 negative myeloproliferative neoplasms (MPNs) form a distinct group of hematologic malignancies characterized by sustained proliferation of cells from multiple myeloid lineages. With a median survival of 16-35 months in patients with high-ri
Externí odkaz:
https://doaj.org/article/9b762eecdb5041ae991b86ec4af8d1a4
Autor:
Marfa Blanter, Maaike Cockx, Liesel Wittebols, Sara Abouelasrar Salama, Mirre De Bondt, Nele Berghmans, Noëmie Pörtner, Lotte Vanbrabant, Natalie Lorent, Mieke Gouwy, Mieke Boon, Sofie Struyf
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for PCD and to date there are no specific treatments available. Neutrophils are a crucial part o
Externí odkaz:
https://doaj.org/article/f1f7b798d1e747da96aade424115f043
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Originally, it was thought that a single serum amyloid A (SAA) protein was involved in amyloid A amyloidosis, but in fact, SAA represents a four‐membered family wherein SAA1 and SAA2 are acute phase proteins (A-SAA). SAA is highly conserved through
Externí odkaz:
https://doaj.org/article/f89a0274955148a2a1992a8dbe679d81
Autor:
Karen Yu, Luna Dillemans, Mieke Gouwy, Helena Bessa, Mieke Metzemaekers, Erik Martens, Patrick Matthys, Xavier Bossuyt, Patrick Verschueren, Carine Wouters, Lien De Somer, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeptidylarginine deiminases (PADs) mediate citrullination, an irreversible posttranslational modification that converts arginine to citrulline residues in proteins. Rheumatoid arthritis (RA) is characterized by unique autoantibodies that
Externí odkaz:
https://doaj.org/article/9ca117eb2c8840c6a6bb1c642c7ab377
Autor:
Bert Malengier-Devlies, Jessica Filtjens, Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Greet Hermans, Philippe Meersseman, Alexander Wilmer, Mieke Gouwy, Abhishek D. Garg, Stephanie Humblet-Baron, Frederik De Smet, Kimberly Martinod, Els Wauters, Paul Proost, Carine Wouters, Georges Leclercq, Diether Lambrechts, Joost Wauters, Patrick Matthys
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we analysed the phenotype and activity of NK cells in the bloo
Externí odkaz:
https://doaj.org/article/13d4db38766a497bbdb3b0ba63a9215a
Autor:
Eva Ganseman, Mieke Gouwy, Dominique M. A. Bullens, Christine Breynaert, Rik Schrijvers, Paul Proost
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 86 (2022)
A significant part of adult-onset asthma is caused by occupational exposure to both high- and low-molecular-mass agents. Insects are occasionally described to cause occupational allergy in professions including anglers and fishers, laboratory workers
Externí odkaz:
https://doaj.org/article/9c5d658c4a494ff5a749458bf5e0556c
Autor:
Marfa Blanter, Seppe Cambier, Mirre De Bondt, Lotte Vanbrabant, Noëmie Pörtner, Sara Abouelasrar Salama, Mieke Metzemaekers, Pedro Elias Marques, Sofie Struyf, Paul Proost, Mieke Gouwy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils are the most abundant leukocytes in human blood and the first cells responding to infection and injury. Due to their limited ex vivo lifespan and the impossibility to cryopreserve or expand them in vitro, neutrophils need to be purified f
Externí odkaz:
https://doaj.org/article/22b2a53576ab4daf8896b0c851e25066