Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mieczyslaw Michalkiewicz"'
Publikováno v:
Hypertension.
Autor:
Ivica Grković, Quinn H. Hogan, Ksenija Modric-Jednacak, Mieczyslaw Michalkiewicz, Damir Sapunar
Publikováno v:
Brain Research. 1063:48-58
In order to clarify the physiologic role of NPY in sensory processing, we obtained intracellular recordings of DRG neurons from wild type (WT) and NPY overexpressing transgenic rats (NPY-TG) before and after injury. We investigated medium and large d
Autor:
Teresa Michalkiewicz, Åke Lernmark, Eric S. Lander, Jessica M. Fuller, Brian Van Yserloo, Ruth A. Ettinger, Anne E. Kwitek, Howard J. Jacob, Armand J. MacMurray, Elizabeth A. Rutledge, Mieczyslaw Michalkiewicz, Daniel H. Moralejo
Publikováno v:
Physiological Genomics. 19:228-232
A single point mutation in a novel immune-associated nucleotide gene 5 ( Ian5) coincides with severe T cell lymphopenia in BB rats. We used a transgenic rescue approach in lymphopenic BB-derived congenic F344. lyp/ lyp rats to determine whether this
Publikováno v:
Hypertension. 41:1056-1062
The neurons that control blood pressure express neuropeptide Y. Administered centrally, this neuropeptide reduces blood pressure and anxiety, together with lowering sympathetic outflow. The generation of neuropeptide Y transgenic rats overexpressing
Publikováno v:
Thyroid. 8:1071-1077
In the present study, we tested the hypothesis that the neuropeptides, vasoactive intestinal peptide (VIP) and neuropeptide Y (NPY), which are present in the thyroid nerves, act as physiological neurotransmitters involved in the regulation of thyroid
Publikováno v:
Peptides. 14:1179-1186
Sympathetic nerve fibers to thyroid blood vessels contain both norepinephrine (NE) and neuropeptide Y (NPY). To assess the involvement of endogenous NPY in the sympathetic neural control of thyroid blood flow, appropriate doses of a selective NPY ant
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 265:E24-E30
It has been suggested that thyroid blood flow is regulated by both sympathetic and parasympathetic nerves. The purpose of our experiments was to study the role of neuropeptide Y (NPY) in the sympathetic neural control of thyroid blood flow. Sympathet
Publikováno v:
Molecular and Cellular Neuroscience. 3:418-424
Both neuropeptide Y (NPY) and vasoactive intestinal peptide (VIP) are present in thyroid nerves and have been shown to alter thyroid activity. The present study was conducted to determine whether hypo- or hyperthyroidism is associated with changes in
Autor:
Jeffrey C. Miller, Adam Wood, Séverine Ménoret, Philip D. Gregory, Bryan Zeitler, Anna I Vincent, Shirin S Jenkins, Rebecca Schilling, Jamie Foeckler, Lei Zhang, Xiaoxia Cui, Shawn Kalloway, Hartmut Weiler, Roland Buelow, Edward J. Rebar, Aron M. Geurts, Ignacio Anegon, Gregory J. Cost, Gregory D. Davis, Fyodor D. Urnov, Vivian M. Choi, Mieczyslaw Michalkiewicz, Yevgeniy Freyvert, Howard J. Jacob, Stephen Lam, Xiangdong Meng
Publikováno v:
Science (New York, N.Y.). 325(5939)
The toolbox of rat genetics currently lacks the ability to introduce site-directed, heritable mutations into the genome to create knockout animals. By using engineered zinc-finger nucleases (ZFNs) designed to target an integrated reporter and two end
Publikováno v:
The FASEB Journal. 22