Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mieczysław Wender"'
Autor:
Dariusz Urbanski, Beata Raczak, Justyna Biernacka-Lukanty, Mieczysław Wender, Wojciech Kozubski, Grazyna Michalowska-Wender, Slawomir Michalak
Publikováno v:
Folia Neuropathologica. 4:343-346
Osteopontin (OPN) is a key cytokine involved in T-cell activation in multiple sclerosis (MS). We investigated whether polymorphism of the osteopontin gene affects MS occurrence and clinical course in a Polish population. Disability in 100 MS patients
Autor:
Wojciech Kozubski, Grzegorz Rossa, Grażyna Michałowska-Wender, Alicja Wawrzynek, Mieczysław Wender
Publikováno v:
Folia Neuropathologica. 4:417-420
Alzheimer disease (AD) is a complex, multi-factorial disease with the potential involvement of several genes. Alpha-2- macroglobulin (A2M) has been implicated in AD on the basis of its ability to mediate the clearance and degradation of -amyloid p
Publikováno v:
Folia Neuropathologica. 3:222-226
Introduction The activity of erythrocyte transketolase induced by thiamine pyrophosphate and normalized to age of the patient is a marker of thiamine metabolism disturbances with pathological consequences in the central and peripheral nervous system.
Publikováno v:
Folia Neuropathologica. 2:127-131
Until now, the question as to the role of immunological mechanisms in neuronal death of extrapyramidal cell systems in Parkinson's disease (PD) has not been fully resolved. One of the approaches includes examination of circulating blood cells. In our
Publikováno v:
Journal of Medical Science, Vol 84, Iss 2 (2015)
The natural course of multiple sclerosis is characterized by a high variability of pattern, relapse rate and different progression indices. They also present a dramatic impact on the interpretation of treatment trials. Older reports, based on uncontr
Autor:
Józef Szczech, Wojciech Kozubski, Anna Kowalska, Jolanta Florczak, Renata Modestowicz, Grzegorz Rossa, Danuta Pruchnik-Wolinska, Mieczysław Wender
Publikováno v:
Acta Biochimica Polonica. 51:245-252
A small number (1-5%) of Alzheimer's disease (AD) cases associated with the early-onset form of the disease (EOAD) appears to be transmitted as a pure genetic, autosomal dominant trait. To date, three genes responsible for familial EOAD have been ide
Autor:
Grażyna, Michałowska-Wender, Alicja, Wawrzynek, Grzegorz, Rossa, Wojciech, Kozubski, Mieczysław, Wender
Publikováno v:
Folia neuropathologica. 52(4)
Alzheimer disease (AD) is a complex, multi-factorial disease with the potential involvement of several genes. Alpha-2- macroglobulin (A2M) has been implicated in AD on the basis of its ability to mediate the clearance and degradation of -amyloid p
Publikováno v:
Reviews on Recent Clinical Trials. 6:256-258
The natural course of multiple sclerosis is characterized by a high variability of pattern, relapse rate and different progression indices. They also present a dramatic impact on the interpretation of treatment trials. Reports, based on uncontrolled
Autor:
Mieczysław Wender, Alicja Wawrzynek, Wojciech Kozubski, Jacek Dobiała, Grazyna Michałowska-Wender
Publikováno v:
Neurologia i neurochirurgia polska. 48(6)
TNFα, a significant immune mediator, may contribute to the initiation and progression of the ischemic stroke. Genetics of TNFα molecule may have an important role in the risk of ischemic stroke. The most interesting aspects of the G-308A polymorphi
Publikováno v:
Acta Neurologica Scandinavica. 89:69-71
The effect of large-dose prednisone therapy (3960 mg over 56 days) on IgG subclasses in the cerebrospinal fluid and sera, as well as on their intrathecal synthesis, was studied in 15 patients with clinically definite multiple sclerosis. The concentra