Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mie Konno"'
Autor:
Angela MY. Chan, Gloria Roldan Urgoiti, Will Jiang, Sandra Lee, Elizabeth Kornaga, Peter Mathen, Rosanna Yeung, Emeka K. Enwere, Alan Box, Mie Konno, Martin Koebel, Kurian Joseph, Corinne M. Doll
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundProgrammed death-ligand 1 (PD-L1) expression has been shown to be prognostic in many cancer types and used in consideration of checkpoint inhibitor immunotherapy. However, there are very limited and conflicting data on the prognostic impact
Externí odkaz:
https://doaj.org/article/c4113dee65734a5691f506b596a4b519
Autor:
Angela MY Chan, Tasnima Abedin, Satbir Thakur, HaoCheng Li, Mie Konno, Emeka Enwere, Sasha Lupichuk, Nancy Nixon, Donald Morris, Hua Yang, Paola Neri
Publikováno v:
Cancer Research. 82:P1-08
Background: Breast cancer prognosis and systemic treatment is mainly determined by its molecular subtype defined by the expression of driver genes including ER, PR, HER2 and Ki67. Several assays which include these key genes are currently available f
Autor:
Don Morris, Mie Konno, Anthony M. Magliocco, Chris T. Williamson, Tyler Williamson, L. Petersen, D. Gwyn Bebb, Desiree Hao, Susan P. Lees-Miller, A. Elegbede, Alexander C. Klimowicz, Stephanie K. Petrillo, S. Otsuka
Publikováno v:
Oncotarget
Ataxia-telangiectasia mutated (ATM) is critical in maintaining genomic integrity. In response to DNA double-strand breaks, ATM phosphorylates downstream proteins involved in cell-cycle checkpoint arrest, DNA repair, and apoptosis. Here we investigate
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Tamoxifen is a key therapeutic option for breast cancer treatment. Understanding its complex metabolism and pharmacokinetics is important for dose optimization. We examined the possibility of utilizing archival formalin-fixed paraffin-embedde
Autor:
Alexander C. Klimowicz, Harold Lau, Shamir P. Chandarana, Pinaki Bose, Steven C. Nakoneshny, Stephanie K. Petrillo, T. Wayne Matthews, Michelle Dean, Anthony M. Magliocco, Luke Rudmik, Joseph C. Dort, Mie Konno, Nigel T. Brockton
Publikováno v:
Oral Oncology. 48:615-622
Every year, approximately 25,000 patients are diagnosed with oral cavity squamous cell carcinoma (OCSCC) in the USA. The 5-year survival rate for OCSCC is approximately 40%. Intratumoral hypoxia confers poor prognosis and treatment failure but direct
Autor:
Olga Kovalchuk, Mie Konno, L. Petersen, Michelle Dean, Gwyn Bebb, Adrijana D'Silva, Y. Ilnytskyy
Publikováno v:
Journal of Thoracic Oncology. 13:S954
Publikováno v:
Journal of Thoracic Oncology. 12:S265
Autor:
Alexander C. Klimowicz, Steven C. Nakoneshny, Shamir P. Chandarana, Luke Rudmik, Anthony M. Magliocco, Joseph C. Dort, Mie Konno, Wayne Matthews, Nigel T. Brockton, Stephanie K. Petrillo, Pinaki Bose
Publikováno v:
Cancer Research. 73:A10-A10
Background: Hypoxia is an almost ubiquitous feature of human solid tumours. However, the direct measurement of oxygen concentration in head and neck squamous cell carcinoma (HNSCC) has been conducted almost exclusively in the metastatic lymph nodes,
Autor:
S. Otsuka, Erin Stolte, William Boland, Huong Muzik, D. Gwyn Bebb, Don Morris, Anthony M. Magliocco, Mie Konno, Alexander C. Klimowicz, Stephanie K. Petrillo, Karen A. Kopciuk, Desiree Hao
Publikováno v:
Journal of Thoracic Oncology. (7):1169-1178
Background It has been proposed that the chemokine receptor, CXCR4, and its ligand, stromal cell-derived factor-1 (SDF-1), play a critical role in organ-specific tumor metastasis. High CXCR4 expression in resected non-small cell lung cancer (NSCLC) t