Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mie Kanda"'
Autor:
Tatsuya Ihara, Hiroshi Shimura, Sachiko Tsuchiya, Mie Kanda, Satoru Kira, Norifumi Sawada, Masayuki Takeda, Takahiko Mitsui, Eiji Shigetomi, Yoichi Shinozaki, Schuichi Koizumi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Dysregulation of circadian rhythm can cause nocturia. Levels of fatty acid metabolites, such as palmitoylethanolamide (PEA), 9-hydroxy-10E,12Z-octadecadienoic acid (9-HODE), and 4-hydroxy-5E,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid (4-HDoHE),
Externí odkaz:
https://doaj.org/article/a2268da3549b4b64bae0bf8a0f7daa57
Autor:
Satoru, Motoyama, Miki, Hosaka, Takashi, Kamei, Masaki, Ueno, Masayuki, Watanabe, Y U, Ohkura, Shinji, Mine, Shunsuke, Tanabe, Takahiro, Toyokawa, Akiyuki, Wakita, Katsunori, Nishikawa, Itasu, Ninomiya, Kazuma, Fujita, Mie, Kanda, Mitsuharu, Hirai, Manami, Hoshi, Shih-Wei, Chiu, Munenori, Takata, Takuhiro, Yamaguchi, Masatomo, Miura
Publikováno v:
Anticancer Research. 42:6105-6112
For patients with T1a muscularis mucosae (MM) esophageal squamous cell carcinoma (ESCC) with lymphovascular invasion (LVI) or T1b submucosal (SM) ESCC, endoscopic resection is non-curative, and adjuvant treatment entailing esophagectomy or definitive
Autor:
Sachiko Tsuchiya, Tatsuya Miyamoto, Norifumi Sawada, Hiroshi Nakagomi, Tatsuya Ihara, Takahiko Mitsui, Mie Kanda, Masayuki Takeda, Satoru Kira, Hiroshi Shimura
Publikováno v:
International Urology and Nephrology. 52:233-238
The present study was conducted to identify metabolites using a metabolomics approach and investigate the relationship between these metabolites and urgency as a major symptom of overactive bladder (OAB). In 47 male participants without any apparent
Autor:
Tatsuya Ihara, Masayuki Takeda, Mie Kanda, Hiroshi Nakagomi, Yuki Nakamura, Mitsuharu Yoshiyama, Eiji Shigetomi, Manabu Kamiyama, Atsuhito Nakao, Satoru Kira, Takahiko Mitsui, Youichi Shinozaki, Schuichi Koizumi, Sachiko Tsuchiya, Norifumi Sawada
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Intermittent stress disrupts the circadian rhythm in clock genes such as Per2 only in peripheral organs without any effect on the central circadian clock in the suprachiasmatic nucleus. Here, the effect of restraint stress (RS) on circadian bladder f
Autor:
Tatsuya Ihara, Schuichi Koizumi, Norifumi Sawada, Eiji Shigetomi, Mie Kanda, Yoichi Shinozaki, Hiroshi Shimura, Satoru Kira, Sachiko Tsuchiya, Takahiko Mitsui, Hiroshi Nakagomi, Masayuki Takeda, Manabu Kamiyama
Publikováno v:
Life sciences. 278
Objectives Nocturia is a major problem in geriatric patients. Clock genes regulate circadian bladder function and Piezo type mechanosensitive ion channel component 1 (Piezo1) that senses bladder fullness. We utilized WT and Clock mutant (ClockΔ19/Δ
Autor:
Manabu Kamiyama, Shuichi Koizumi, Takahiko Mitsui, Norifumi Sawada, Sachiko Tsuchiya, Masayuki Takeda, Hiroshi Nakagomi, Yoichi Shinozaki, Mie Kanda, Satoru Kira, Tatsuya Ihara
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:It is reported that the bladder functions are under the regulation of clock genes, which regulate circadian rhythm in organisms, and dysregulation of circadian bladder fu...
Autor:
Mie Kanda, Manabu Kamiyama, Mitsuharu Yoshiyama, Masayuki Takeda, Schuichi Koizumi, Norifumi Sawada, Tatsuya Ihara, Yuki Nakamura, Satoru Kira, Youichi Shinozaki, Eiji Shigetomi, Atsuhito Nakao, Takahiko Mitsui, Hiroshi Nakagomi, Sachiko Tsuchiya
Publikováno v:
Neurourology and Urodynamics. 37:2535-2543
Aims The sensation of bladder fullness (SBF) is triggered by the release of ATP. Therefore, the aim of this study was to investigate whether time-dependent changes in the levels of stretch-released ATP in mouse primary-cultured urothelial cells (MPCU
Autor:
Hiroshi Nakagomi, Masayuki Takeda, Tatsuya Ihara, Sachiko Tsuchiya, Tatsuya Miyamoto, Takahiko Mitsui, Mie Kanda, Norifumi Sawada, Satoru Kira, Hiroshi Shimura
Publikováno v:
Urology. 118:158-163
Objectives To identify metabolites that are associated with an overactive bladder (OAB) using metabolomics. Materials and Methods A total of 58 male patients without apparent neurologic disease completed 24-hour bladder diaries of their micturition b
Autor:
Manabu Kamiyama, Masayuki Takeda, Sachiko Tsuchiya, Eiji Shigetomi, Yuri Hirayama, Norifumi Sawada, Hiroshi Nakagomi, Yuki Nakamura, Youichi Shinozaki, Schuichi Koizumi, Mitsuharu Yoshiyama, Atsuhito Nakao, Satoru Kira, Mie Kanda, Takahiko Mitsui, Tatsuya Ihara
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
We previously showed that bladder functions are controlled by clock genes with circadian rhythm. The sensation of bladder fullness (SBF) is sensed by mechano-sensor such as Piezo1 and TRPV4 in the mouse bladder urothelium. However, functional circadi
Autor:
Norifumi Sawada, Eiji Shigetomi, Masayuki Takeda, Mitsuharu Yoshiyama, Hiroshi Nakagomi, Yuri Hirayama, Keisuke Shibata, Atsuhito Nakao, Mie Kanda, Schuichi Koizumi, Yuki Nakamura, Yoichi Shinozaki, Tatsuya Ihara, Satoru Kira, Sachiko Tsuchiya, Takahiko Mitsui
Publikováno v:
Neurourology and Urodynamics. 37:942-951
Aims To investigate circadian gene expressions in the mouse bladder urothelium to establish an experimental model and study the functions of the circadian rhythm. Methods The gene expression rhythms of the clock genes, mechano-sensors such as Piezo1