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Autor:
Kenji Miyata, Takuji Mizui, Seijiro Hara, Ken-ichi Higashino, Yasumasa Goh, Kanya Tonda, Nobuo Takasu, Mie Iwai, Junko Higaki, Kiyoshi Nagata
Publikováno v:
Life sciences. 60(24)
The ileal Na+/bile acid cotransporter (IBAT) maintains the reabsorption of bile acids from the intestine in the enterohepatic circulation of bile acids. In the present study, we showed that S-8921 could dose-dependently inhibit the uptake of [ 3 H]ta