Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-β Protein Production

Autor: Eggert, Simone, Midthune, Brea, Cottrell, Barbara, Koo, Edward H.

Publikováno v: In Journal of Biological Chemistry 16 October 2009 284(42):28943-28952

The role of amyloid precursor protein in amyloid-beta- mediated synaptic dysfunction

Autor: Midthune, Brea June

Publikováno v: Midthune, Brea June; & Midthune, Brea June. (2012). The role of amyloid precursor protein in amyloid-beta-mediated synaptic dysfunction. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9fx3n5hs

Amyloid precursor protein (APP) is a type one transmembrane protein and has two mammalian homologues, amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2). APP is the parent molecule to amyloid-[beta] (A[beta]), the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::92a30bfa0f7ca15a90caa4627b505eba
http://www.escholarship.org/uc/item/9fx3n5hs

Elimination of APP caspase cleavage site D664 attenuates Aβ-mediated synaptic depression

Autor: Midthune, Brea, Malinow, Roberto, Koo, Edward

Publikováno v: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2011 7(4) Supplement:S588-S588

Comparison of neuronal morphology in pyramidal neurons of the CA1, dentate gyrus, and prefrontal cortex of APP knockout and APLP2 knockout mice

Autor: Walsh, Jessica J., Tyan, Sheue-Houy, Midthune, Brea, Yu-Jung Shih, Ann, Eggert, Simone, Hof, Patrick R., Koo, Edward, Dickstein, Dara L.

Publikováno v: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2010 6(4) Supplement:S213-S213

ChemInform Abstract: Current Challenges in Nucleic Acid Synthesis.

Autor: Hogrefe, Richard I., Midthune, Brea, Lebedev, Alexandre

Publikováno v: ChemInform; Oct2013, Vol. 44 Issue 41, pno-no, 1p