Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Midori Shimamura"'
Publikováno v:
Life Sciences. 88:411-417
Aims An automated experimental system applying a commercially available video image analyzer was developed for the simultaneous detection and measurement of three behavioral components; immobility, swimming (horizontal movements) and climbing (vertic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3aa50ea447e7a35aa248a3068d37fe
https://doi.org/10.1016/j.lfs.2010.12.016
https://doi.org/10.1016/j.lfs.2010.12.016
Autor:
Jeffrey J. Legos, Frank C. Barone, Raymond F. White, Hideo Kikkawa, Mine Kinoshita, Matthew E Barton, Kazuyoshi Kuratani, Midori Shimamura
Publikováno v:
Pharmacology. 81:11-17
Background/Aims: Phosphodiesterase type 4 (PDE4) has been previously shown to regulate colonic contractile activity in vitro. In this study, the effects of PDE4 inhibition were assessed in a model of stress-induced defecation previously demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbda701d44e19ea4092ee28b1e42fe6
https://doi.org/10.1159/000107662
https://doi.org/10.1159/000107662
Publikováno v:
Psychopharmacology. 197(4)
Marble burying and forced swimming behavior are widely used and sensitive tests for identifying clinically effective antidepressant drugs, although the underlying neurobiology of these behaviors is not fully elucidated.The objective of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3d3ac263fccde38ce00f2c4542c0ba
https://pubmed.ncbi.nlm.nih.gov/18274731
https://pubmed.ncbi.nlm.nih.gov/18274731
Publikováno v:
Journal of pharmacological and toxicological methods. 57(1)
Introduction: In most publications on the forced swim test studies, duration of immobility is measured during the last 4 min of the 6-min testing period as a marker for depression. However, it is not clear if 4-min span best captures antidepressant-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6099b1a1d1958d4e000726556d8380de
https://pubmed.ncbi.nlm.nih.gov/17980628
https://pubmed.ncbi.nlm.nih.gov/17980628
Publikováno v:
Journal of pharmacological and toxicological methods. 55(3)
Introduction MicroAct™ (Neuroscience, Tokyo, Japan) was originally developed as a new system for an automated analysis of scratching behaviors in mice. This system is based on the detection of electric current in the coils according to the movement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10262e6586e00149032b6cdd989dad1d
https://pubmed.ncbi.nlm.nih.gov/17218117
https://pubmed.ncbi.nlm.nih.gov/17218117