Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Midori Shimada"'
Autor:
Yuki Sato, Makoto Habara, Shunsuke Hanaki, Jafar Sharif, Haruki Tomiyasu, Yosei Miki, Midori Shimada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Excess amounts of histones in the cell induce mitotic chromosome loss and genomic instability, and are therefore detrimental to cell survival. In yeast, excess histones are degraded by the proteasome mediated via the DNA damage response fact
Externí odkaz:
https://doaj.org/article/1cb3bae62c394f73a63fa21a2a33d3d4
Autor:
Hiromi Tomono, Hirokazu Taniguchi, Minoru Fukuda, Takaya Ikeda, Seiji Nagashima, Kazumasa Akagi, Sawana Ono, Yasuhiro Umeyama, Midori Shimada, Hiroshi Gyotoku, Shinnosuke Takemoto, Yasushi Hisamatsu, Ryotaro Morinaga, Ryuta Tagawa, Ryosuke Ogata, Yosuke Dotsu, Hiroaki Senju, Hiroshi Soda, Katsumi Nakatomi, Fumiko Hayashi, Nanae Sugasaki, Akitoshi Kinoshita, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 14, Iss 28, Pp 2890-2894 (2023)
Abstract Introduction Combined treatment using anti‐programmed death‐ligand 1 antibody (anti‐PD‐L1) and platinum‐etoposide is the current standard first‐line treatment for patients with extensive‐stage (ES) small cell lung cancer (SCLC)
Externí odkaz:
https://doaj.org/article/58002b57502d40c3b42c6726aa5a9340
Autor:
Takahiro Masaki, Makoto Habara, Shunsuke Hanaki, Yuki Sato, Haruki Tomiyasu, Yosei Miki, Midori Shimada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract c-Myc, a transcription factor, induces cell proliferation and is often aberrantly or highly expressed in cancers. However, molecular mechanisms underlying this aberrantly high expression remain unclear. Here, we found that intracellular Ca2+
Externí odkaz:
https://doaj.org/article/77f7ecf5932e451dacab6d48fd6924aa
Autor:
Ryosuke Ogata, Hiroshi Soda, Hiroaki Senju, Masaki Fujioka, Midori Shimada, Koki Yamashita, Satoshi Irifune, Ryuta Tagawa, Yosuke Dotsu, Keisuke Iwasaki, Hirokazu Taniguchi, Shinnosuke Takemoto, Yuichi Fukuda, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 13, Iss 19, Pp 2812-2816 (2022)
Abstract Extraskeletal myxoid chondrosarcoma (EMCS) is an undifferentiated mesenchymal malignancy; however, its immune microenvironment remains to be elucidated. The case of a 34‐year‐old woman who developed EMCS metastasizing to the pleura is pr
Externí odkaz:
https://doaj.org/article/a21fc35aa6c24911b5adf1ac1b07f36d
Autor:
Kazumasa Akagi, Hirokazu Taniguchi, Minoru Fukuda, Takuya Yamazaki, Sawana Ono, Hiromi Tomono, Takayuki Suyama, Midori Shimada, Hiroshi Gyotoku, Shinnosuke Takemoto, Hiroyuki Yamaguchi, Yosuke Dotsu, Hiroaki Senju, Hiroshi Soda, Takashi Mizowaki, Yoshio Monzen, Takaya Ikeda, Seiji Nagashima, Yutaro Tasaki, Daisuke Nakamura, Kazutoshi Komiya, Katsumi Nakatomi, Eisuke Sasaki, Koichi Hirakawa, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 13, Iss 16, Pp 2404-2409 (2022)
Abstract Background Etoposide plus cisplatin (EP) combined with concurrent accelerated hyperfractionated thoracic radiotherapy (AHTRT) is the standard treatment strategy for unresectable limited‐disease (LD) small cell lung cancer (SCLC), which has
Externí odkaz:
https://doaj.org/article/e98bad858982435187389e1927d39f13
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells
Autor:
Keisuke Maeda, Makoto Habara, Mitsuyasu Kawaguchi, Hiroaki Matsumoto, Shunsuke Hanaki, Takahiro Masaki, Yuki Sato, Hideyasu Matsuyama, Kazuki Kunieda, Hidehiko Nakagawa, Midori Shimada
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 940-956 (2022)
The growth of prostate cancer is dependent on the androgen receptor (AR), which serves as a ligand‐specific transcription factor. Although two immunophilins, FKBP51 and FKBP52, are known to regulate AR activity, the precise mechanism remains unclea
Externí odkaz:
https://doaj.org/article/f09ae7f5c53f4b779fe5929a3187c622
Autor:
Ryosuke Ogata, Hiroshi Soda, Yasuhiro Tanaka, Hiroaki Senju, Midori Shimada, Koki Yamashita, Shota Nakashima, Asuka Umemura, Masataka Yoshida, Takuya Hara, Saeko Jinnai, Keisuke Iwasaki, Yuichi Fukuda, Hiroyuki Yamaguchi, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 13, Iss 1, Pp 133-136 (2022)
Abstract How Epstein–Barr virus (EBV)‐positive diffuse large B‐cell lymphoma (DLBCL) occasionally occurs following chronic inflammation remains to be elucidated. The case of a 57‐year‐old man who developed pulmonary EBV‐positive DLBCL fro
Externí odkaz:
https://doaj.org/article/b61746868d1048ba9d655c3efbd480dc
Autor:
Takaya Ikeda, Shinnosuke Takemoto, Hiroaki Senju, Hiroshi Gyotoku, Hirokazu Taniguchi, Midori Shimada, Yosuke Dotsu, Yasuhiro Umeyama, Hiromi Tomono, Takeshi Kitazaki, Masaaki Fukuda, Hiroshi Soda, Hiroyuki Yamaguchi, Minoru Fukuda, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 11, Iss 7, Pp 1972-1978 (2020)
Background The aim of this study was to assess the efficacy and safety of amrubicin for previously treated malignant pleural mesothelioma. Methods The eligibility criteria were: previously treated unresectable malignant pleural mesothelioma; performa
Externí odkaz:
https://doaj.org/article/b8beb7e2f14e48d293606d434ed3eea7
Autor:
Yasuhiro Tanaka, Hiroshi Soda, Yuichi Fukuda, Kenta Nio, Sawana Ono, Hiromi Tomono, Midori Shimada, Masataka Yoshida, Tatsuhiko Harada, Asuka Umemura, Keisuke Iwasaki, Hiroyuki Yamaguchi, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 11, Iss 2, Pp 470-474 (2020)
The association between gut microbiota and the lung immune system has been attracting increasing interest. Here, we report a case of pancreatic cancer in which the dipeptidyl peptidase‐4 inhibitor vildagliptin induced unusual manifestations of inte
Externí odkaz:
https://doaj.org/article/ed68d9174640454baf258f2a359c6d9f
Autor:
Hiromi Tomono, Hiroshi Soda, Yuichi Fukuda, Yasuhiro Tanaka, Sawana Ono, Midori Shimada, Keisuke Iwasaki, Masashi Hisanaga, Hiroyuki Yamaguchi, Hiroshi Mukae
Publikováno v:
Thoracic Cancer, Vol 10, Iss 10, Pp 2026-2030 (2019)
Immunoglobulin light‐chain (AL) amyloidosis is a monoclonal plasma cell neoplasm that has a tendency to bleed easily. However, the potential risks of transbronchial biopsy in such cases have not been fully proven. Here, we report a case of parotid
Externí odkaz:
https://doaj.org/article/f68a87343ff04512bc404c22ab4285b2