Výsledky vyhledávání - "Midori Komatsu"

Antitumor Effect of Trastuzumab for Pancreatic Cancer with High HER-2 Expression and Enhancement of Effect by Combined Therapy with Gemcitabine

Autor: Kenjiro Kimura, Tetsuji Sawada, Nobuya Yamada, Masaichi Ohira, Midori Komatsu, Masafumi Inoue, Yoshito Yamashita, Kazuya Muguruma, Kosei Hirakawa, Tamahiro Nishihara

Publikováno v: Clinical Cancer Research. 12:4925-4932

Purpose: The purpose of the present study was to evaluate whether trastuzumab has antitumor effect against pancreatic cancer and whether this effect is concordant with levels of HER-2, which is reportedly overexpressed in pancreatic cancer. We also i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc186a91ea5561f477b38326c94700c
https://doi.org/10.1158/1078-0432.ccr-06-0544

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Development of novel humanized anti-CD20 antibodies based on affinity constant and epitope

Autor: Midori Komatsu, Tetsuji Sawada, Yasuhiko Suzuki, Susumu Uchiyama, Shuichi Aikawa, Yasuo Morishima, Yoshitoyo Kagami, Kentaro Otake, Masami Yokoyama, Kiichi Fukui, Mitsuo Ohta

Publikováno v: Cancer science. 101(1)

We describe novel humanized anti-CD20 monoclonal antibodies (mAbs) developed for therapeutic use on the basis of their physicochemical properties and cellular cytotoxicity. A distinct correlation between apparent dissociation constants (K(d)) and apo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098f0efbd4095097cc3a59d980000b97
https://pubmed.ncbi.nlm.nih.gov/19930155

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A novel angiogenesis inhibitor, Ki23057, is useful for preventing the progression of colon cancer and the spreading of cancer cells to the liver

Autor: Midori Komatsu, Nobuya Yamada, Taro Matsuzaki, Masaichi Ohira, Atsushi Miwa, Katsunobu Sakurai, Kosei Hirakawa, Masakazu Yashiro

Publikováno v: European journal of cancer (Oxford, England : 1990). 43(17)

Ki23057 is a new, small synthetic tyrosine kinase inhibitor that blocks autophosphorylation of the VEGF receptor2 (VEGFR2). To determine the effect of Ki23057 as an anti-angiogenic agent, we studied the effect of Ki23057 for colon cancer and vascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f90a7a9eda4a3c3f34f5951510603de
https://pubmed.ncbi.nlm.nih.gov/17949968

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Characterization of novel murine anti-CD20 monoclonal antibodies and their comparison to 2B8 and c2B8 (rituximab)

Autor: Sadakazu Usuda, Midori Komatsu, Hiroshi Hanaoka, Keisuke Teshigawara, Michio Nishida, Hiroko Miyakoda, Otsura Niwa, Masato Okabe

Publikováno v: International journal of oncology. 31(1)

Rituximab is the first anti-cancer antibody approved by the FDA for the treatment of B-cell non-Hodgkin lymphoma (B-NHL), alone or in combination with chemotherapeutic drugs. Further, rituximab is now being examined in a variety of CD20+ neoplastic d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93964d2c7aa745627e58391e6f58da11
https://pubmed.ncbi.nlm.nih.gov/17549402

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ON THE RELATIONSHIP BETWEEN DOMINANT PACEMAKER POTENTIALS AND APPLIED TRANSMEMBRANE CURRENT BY USE OF TWO BARRELS GLASSMICROELECTRODES

Autor: Midori Komatsu, Kashima Goto

Publikováno v: The KITAKANTO Medical Journal. 26:459-467

On the isolated frog's S-A node is investigated the relationship between dominant pacemaker potentials and applied transmembrane current by use of two barrels glassmicroelectrodes. namely, the dominant pacemaker potentials are recorded with one elect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b82fe3f1bad2c73a309860377b6e7f2
https://doi.org/10.2974/kmj1951.26.459

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Lesion localization in aphasia without hemiparesis

Autor: Yoko Senoh, Midori Komatsu, Koichi Okamoto, Mitsunori Morimatsu, Shunsaku Hirai

Publikováno v: Nosotchu. 5:143-149

麻痺をほとんど認めない失語症18例の病巣部位検索を主にCTを用いて行った.運動失語群は臨床的には非典型例で病巣も極めて限局性であった.感覚失語群は左上側頭回を中心に時に縁上回�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a161c02d88f970379ee7e4a66f7b1619
https://doi.org/10.3995/jstroke.5.143

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REHABILITATION OF RHEUMATOID ARTHRITIS A CASE REPORT

Autor: Shunsaku Hirai, Midori Komatsu

Publikováno v: The KITAKANTO Medical Journal. 33:487-491

Rehabilitation of rheumatoid arthritis (RA) is troublesome for its variable and unsettled symptoms but physical therapy remains a keystone of treatment.A case of RA, a 48-year-old woman with deformities of all extremities, compression fractures in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::125f98f6c058b64f71a285030de5315f
https://doi.org/10.2974/kmj1951.33.487

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