Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Midori Kayahara"'
Publikováno v:
Clinical Endocrinology. 75:31-38
Context:? Corticosteroid-binding globulin (CBG) is the principal carrier of natural glucocorticoids in the circulation and we hypothesized that it modulates glucocorticoid bioactivity. Alterations in CBG, the presence of non-cortisol, naturally occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0206ded14732d1f507da379d8783fef0
https://doi.org/10.1111/j.1365-2265.2011.04003.x
https://doi.org/10.1111/j.1365-2265.2011.04003.x
Autor:
Vasken Ohanian, Andrew Berry, David W. Ray, Midori Kayahara, Ratna K Vadlamudi, Jacqueline Ohanian
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism
Glucocorticoids are potent anti-inflammatory agents, acting through the glucocorticoid receptor (GR) to regulate target gene transcription. However, GR may also exert acute effects, including activation of signaling kinases such as c-Src and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14772439ee7e1114cc18ba934c6d7d67
https://doi.org/10.1152/ajpendo.90429.2008
https://doi.org/10.1152/ajpendo.90429.2008
Autor:
Midori Kayahara, Cathy Tournier, Emmanouil S. Papadakis, Elizabeth J. Cartwright, Chun Guo, Ulrike Mayer, Jan Seyfried, Anita J. Merritt, Xin Wang, Jill Dixon, Raymond P. Boot-Handford, Katherine G. Finegan
Publikováno v:
Molecular and Cellular Biology. 25:336-345
To elucidate the physiological significance of MEK5 in vivo, we have examined the effect of mek5 gene elimination in mice. Heterozygous mice appear to be healthy and were fertile. However, mek5(-/-) embryos die at approximately embryonic day 10.5 (E1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f705e15c451fc1fbff7c46c0a295ffcd
https://doi.org/10.1128/mcb.25.1.336-345.2005
https://doi.org/10.1128/mcb.25.1.336-345.2005
Autor:
Andrew S. I. Loudon, John Blaikley, Stuart N. Farrow, Simon Lea, Midori Kayahara, Julie E. Gibbs, David W. Ray, Dave Singh
Publikováno v:
B101. INNATE IMMUNE REGULATION OF AIRWAY INFLAMMATION.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2e28e982cef0a8f6667c0c675ac5db
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3786
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3786
Autor:
Anne White, Paula Sommer, H Gillingham, Andrew Berry, Midori Kayahara, T Huynh, P. Le Rouzic, David W. Ray
Publikováno v:
Oncogene. 26(50)
Small cell lung cancer (SCLC) is an aggressive tumour with an abysmal prognosis. These cancers are characteristically resistant to glucocorticoid (Gc) action, owing to impaired expression of the glucocorticoid receptor (GR). We identified reduced GR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72438635e3775a61c5740ea9937df24d
https://pubmed.ncbi.nlm.nih.gov/17496926
https://pubmed.ncbi.nlm.nih.gov/17496926
Autor:
Andrew C Robinson, Cathy Tournier, Midori Kayahara, Katherine G. Finegan, Xin Wang, Emmanouil S. Papadakis, Chun Guo
Publikováno v:
FEBS letters. 580(5)
The signaling mechanism by which JNK affects mitochondria is critical to initiate apoptosis. Here we show that the absence of JNK provides a partial resistance to the toxic effect of the heavy metal cadmium. Both wild type and jnk−/− fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b75da850059afb3a4c1c94d16f694f
https://pubmed.ncbi.nlm.nih.gov/16458303
https://pubmed.ncbi.nlm.nih.gov/16458303
Publikováno v:
Molecular and cellular biology. 25(9)
To further understand how the mitogen-activated protein kinase (MAPK) signaling pathways regulate AP-1 activity, we have elucidated the physiological role of these cascades in the regulation of c-jun gene expression. c-Jun is a crucial component of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f28cb8ff7b978172f8fb9538a30a88
https://pubmed.ncbi.nlm.nih.gov/15831482
https://pubmed.ncbi.nlm.nih.gov/15831482
Publikováno v:
Biochemical Society Transactions. 26:S340-S340
Nitric oxide and its redox related species exhibit both neuroprotective and neurotoxic effects. It has been suggested that the nitrosonium cation (NO') is neuroprotective towards NMDA toxicity, while the free radical nitric oxide (NO') is itself neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c1bc9b0deb36fc1d058b857711bb82
https://doi.org/10.1042/bst026s340
https://doi.org/10.1042/bst026s340
Autor:
Midori Kayahara, A. David Edwards, Kirsty Greenwood, Martin N. Hughes, Mary Kozma, Huseyin Mehmet
Publikováno v:
Pediatric Research. 42:411-411
Background: Nitric oxide (NO•) is known to be both neurotoxic and neuroprotective. There are three redox-related species: neutral NO•, the nitroxyl anion (NO-) and the nitrosonium cation(NO+).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1eba7188160fec9a1411df5addcaabe
https://doi.org/10.1203/00006450-199709000-00178
https://doi.org/10.1203/00006450-199709000-00178
Autor:
A D. Edwards, H. Mehmet, Midori Kayahara, C. Sarraf, Martin N. Hughes, S. Khan, Umesh Joashi, Nicholas D. Mazarakis
Publikováno v:
Europe PubMed Central
King's College London
King's College London
We have investigated the effect of nitric oxide (NO) on apoptosis in Swiss 3T3 fibroblasts and compared it to the effect of the nitrosonium cation (NO+). Both species induced apoptosis, confirmed by electron microscopy, propidium iodide staining, DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e07bae1c922caa9bae69f6621c4687
http://europepmc.org/abstract/med/9378780
http://europepmc.org/abstract/med/9378780
