Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Midori Greenwood-Goodwin"'
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTHost cell proteins (HCPs) are process-related impurities derived from the manufacturing of recombinant biotherapeutics. Residual HCP in drug products, ranging from 1 to 100 ppm (ng HCP/mg product) or even below sub-ppm level, may affect produ
Externí odkaz:
https://doaj.org/article/273decb2ae694d2098838e32ef9d9bf5
Autor:
Feng Yang, Delia Li, Regina Kufer, Lance Cadang, Jennifer Zhang, Lu Dai, Jia Guo, Stefanie Wohlrab, Midori Greenwood-Goodwin, Amy Shen, Dana Duan, Hong Li, Inn H. Yuk
Publikováno v:
Analytical Chemistry. 94:723-731
Residual host cell proteins (HCPs) in the drug product can affect product quality, stability, and/or safety. In particular, highly active hydrolytic enzymes at sub-ppm levels can negatively impact the shelf life of drug products but are challenging t
Autor:
Ben Haley, Marie Kern, Inn H. Yuk, Dana Duan, Shahram Misaghi, Midori Greenwood-Goodwin, Joseph Carver, Amy Shen, Peggy Ko, X. Christopher Yu, Danming Tang, Simon Auslaender
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7414882d1e3e5514268e1fa10b98cb33
https://doi.org/10.1002/btpr.3212/v2/response1
https://doi.org/10.1002/btpr.3212/v2/response1
Autor:
Shahram Misaghi, X. Christopher Yu, Peggy Ko, Joseph Carver, Dana Duan, Simon Auslaender, Marie Kern, Danming Tang, Inn H. Yuk, Amy Shen, Ben Haley, Midori Greenwood-Goodwin
Publikováno v:
Biotechnology progressREFERENCES. 38(1)
Chinese hamster ovary (CHO) cell engineering based on CRISPR/Cas9 knockout (KO) technology requires the delivery of guide RNA (gRNA) and Cas9 enzyme for efficient gene targeting. With an ever-increasing list of promising gene targets, developing and
Publikováno v:
Biomater. Sci.. 2:1627-1639
Engineered biomimetic microenvironments from hydrogels are an emerging strategy to achieve lineage-specific differentiation in vitro. In addition to recapitulating critical matrix cues found in the native three-dimensional (3D) niche, the hydrogel ca
Publikováno v:
Scientific Reports
Pericytes (PCs) are endothelium-associated cells that play an important role in normal vascular function and maintenance. We developed a method comparable to GMP quality protocols for deriving self-renewing perivascular progenitors from the human emb
Publikováno v:
Biomimetic Approaches for Biomaterials Development