Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Midori, Oyama"'
Autor:
Tomoharu Takeuchi, Risa Nakamura, Megumi Hamasaki, Midori Oyama, Shinjiro Hamano, Tomomi Hatanaka
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Objective Galectins are sugar-binding proteins that participate in many biological processes, such as immunity, by regulating host immune cells and their direct interaction with pathogens. They are involved in mediating infection by Schistos
Externí odkaz:
https://doaj.org/article/026fa76716be47e183aa3601d911ee45
Publikováno v:
BioTech, Vol 13, Iss 1, p 6 (2024)
Chitosan, a natural cationic polysaccharide derived from crustaceans and shellfish shells, is known for its advantageous biological properties, including biodegradability, biocompatibility, and antibacterial activity. Chitosan and its composite mater
Externí odkaz:
https://doaj.org/article/4a84101e919d49009afe8f5c7d256b4c
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 121 (2024)
Galectin-1 (Gal-1) is an evolutionarily conserved sugar-binding protein found in intra- and extracellular spaces. Extracellularly, it binds to glycoconjugates with β-galactoside(s) and functions in various biological phenomena, including immunity, c
Externí odkaz:
https://doaj.org/article/f6ae3e0707d14477814cf4f8d83099c7
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Kariya, Oyama et al. propose that αvβ3 can drive a partial EMT phenotype characterized by maintained E-cadherin expression and upregulation of mesenchymal markers. This hybrid EMT state is independent of TGF-β1 signaling and characterised by incre
Externí odkaz:
https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
Autor:
Tomomi Hatanaka, Khampeeraphan Ramphai, Shun Takimoto, Hiromi Kanda, Nami Motosugi, Minoru Kimura, Tomotaka Mabuchi, Midori Oyama, Tomoharu Takeuchi, Yosuke Okamura
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 431 (2022)
Xeroderma pigmentosum (XP) is a rare autosomal recessive hereditary disorder. As patients with XP are deficient in nucleotide excision repair, they show severe photosensitivity symptoms. Although skin protection from ultraviolet (UV) radiation is ess
Externí odkaz:
https://doaj.org/article/38054268e43c42d1a86a978a9aabf578
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1323 (2021)
Osteopontin (OPN) plays a pivotal role in cancer cell invasion and metastasis. Although OPN has a large number of phosphorylation sites, the functional significance of OPN phosphorylation in cancer cell motility remains unclear. In this study, we att
Externí odkaz:
https://doaj.org/article/d8515ac42dc046f99117c45db7a909ef
Expression of galectin-3 in WT-β4-integrin expressing MDA-MB435S cells treated with galectin-3 shRNA or control shRNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0583c485dca0768d2d725008d26bb78f
https://doi.org/10.1158/1541-7786.22512435
https://doi.org/10.1158/1541-7786.22512435
Malignant transformation is associated with aberrant N-glycosylation, but the role of protein N-glycosylation in cancer progression remains poorly defined. β4-integrin is a major carrier of N-glycans and is associated with poor prognosis, tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7693e77a31a74fd0b5e79ed89ecdc5f2
https://doi.org/10.1158/1541-7786.c.6540243.v1
https://doi.org/10.1158/1541-7786.c.6540243.v1
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology
Communications Biology
Epithelial–mesenchymal transition (EMT) plays a pivotal role for tumor progression. Recent studies have revealed the existence of distinct intermediate states in EMT (partial EMT); however, the mechanisms underlying partial EMT are not fully unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5892e7c65711ea9f71325c40e25895aa
https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
https://doaj.org/article/d8dded810a1f4dd2ba943cbec8b2bb05
Autor:
Tomomi Hatanaka, Tomoharu Takeuchi, Yasuhiro Horimoto, Yoichiro Arata, Mayumi Tamura, Midori Oyama, Sachie Nakatani, Kenji Kobata
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1501-1505
Osteoclasts are the only bone-resorbing cells in organisms and understanding their differentiation mechanism is crucial for the treatment of osteoporosis. In the present study, we investigated the effect of Thiamet G, an O-GlcNAcase specific inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f998d51f55e58246a3ca7a8edf5a08
https://doi.org/10.1248/bpb.b20-00221
https://doi.org/10.1248/bpb.b20-00221