Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Midori, Hirai"'
Autor:
Takeshi Ioroi, Naomi Kiyota, Yoshinori Imamura, Masaaki Tanda, Shiori Aoki, Mamoru Okuno, Kazuhiro Yamamoto, Ryohei Sasaki, Ken-ichi Nibu, Hironobu Minami, Midori Hirai, Ikuko Yano
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-8 (2020)
Abstract Background Oral mucositis frequently occurs in cancer patients treated with chemotherapy and chemoradiotherapy (CRT). This study examined the safety and efficacy of ibuprofen gargle in healthy volunteers and patients with chemotherapy- and c
Externí odkaz:
https://doaj.org/article/29a708ee4e4340a48eeba10dc14bc6e1
Autor:
Takahiro Ito, Kazuhiro Yamamoto, Fuminori Ohsawa, Ikuo Otsuka, Akitoyo Hishimoto, Ichiro Sora, Midori Hirai, Ikuko Yano
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 4, Iss 1, Pp 1-6 (2018)
Abstract Background Risperidone is mainly metabolized by cytochrome P450 (CYP) 2D6 in the liver. The gene encoding CYP2D6 is highly polymorphic. The average steady-state plasma concentration of risperidone active moiety is higher in the CYP2D6 interm
Externí odkaz:
https://doaj.org/article/13a52d6a45f148f49d989d5782fc0a9b
Autor:
Marino Bellini, Katia Maso, Ilaria Marigo, Antonella Grigoletto, Hiroki Yoshioka, Vincenzo Ingangi, Kamiya Masaki, Midori Hirai, Lucia Raccagni, Akira Suzuki, Gianfranco Pasut
Publikováno v:
Journal of Controlled Release. 324:228-237
Poly(L-glutamic acid)-co-poly(ethylene glycol) block copolymers (PLE-PEG) are here investigated as polymers for conjugation to therapeutic proteins such as granulocyte colony stimulating factor (G-CSF) and human growth hormone (hGH). PLE-PEG block co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a92e016224131b8a36df32a187b5d3
https://doi.org/10.1016/j.jconrel.2020.05.015
https://doi.org/10.1016/j.jconrel.2020.05.015
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 9, Pp 748-756 (2012)
Objective: Chemotherapy-related toxicities are difficult to predict before treatment. In this study, we investigated whether thyroid hormone receptor beta (THRB) genetic polymorphisms can serve as a potential biomarker in patients with esophageal squ
Externí odkaz:
https://doaj.org/article/ffaef5b8c2fb420f955489beba78bcb1
Autor:
Takeshi Ioroi, Tatsuyuki Kakuma, Akihiro Sakashita, Yuki Miki, Kanako Ohtagaki, Yuka Fujiwara, Yuko Utsubo, Yoshihiro Nishimura, Midori Hirai
Publikováno v:
SAGE Open Medicine, Vol 3 (2015)
Objectives: Studies of palliative care are often performed using single-arm pre–post study designs that lack causal inference. Thus, in this study, we propose a novel data analysis approach that incorporates risk factors from single-arm studies ins
Externí odkaz:
https://doaj.org/article/33bfdc8d6de64ec3b540cd45b8bf0a33
Autor:
Takaki Tanifuji, Ikuo Otsuka, Satoshi Okazaki, Tadasu Horai, Ryuhei So, Kyoichi Shiroiwa, Kentaro Mouri, Motofumi Tanaka, Nobuko Ohmoto, Ichiro Sora, Midori Hirai, Takumi Fukumoto, Yonson Ku, Akitoyo Hishimoto
Publikováno v:
Asian Journal of Psychiatry. 78:103282
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df4ad2951a1d5edeef9fd1a13b17d791
https://doi.org/10.1016/j.ajp.2022.103282
https://doi.org/10.1016/j.ajp.2022.103282
Autor:
Takeshi Ioroi, Motohiro Yamamori, Keiko Yagi, Midori Hirai, Yumei Zhan, Shokei Kim, Hiroshi Iwao
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 2, Pp 145-148 (2003)
The mitogen≫activated protein (MAP) kinase pathways has been shown to be necessary for mitogen-stimulated proliferation, but its role in cell migration has not been fully understood. In this study, we investigated the possible contribution of signa
Externí odkaz:
https://doaj.org/article/fb733cc726f94ac1a02f74f5b38c5f59
Autor:
Kazuhiro Yamamoto, Midori Hirai, Honami Kojima, Atsushi Uda, Tamami Haraguchi, Miyako Yoshida, Ikuo Kawasaki, Minoru Ozeki, Takahiro Uchida, Ikuko Yano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:404-409
The purpose of the study was to evaluate the ability of different beverages to mask the bitterness of zopiclone and eszopiclone in tablet formulations using the artificial taste sensor and human gustatory sensation testing. The beverages tested for b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceef4dcad2e3f873e5e3f48d74e2dbf
https://doi.org/10.1248/cpb.c18-00502
https://doi.org/10.1248/cpb.c18-00502
Autor:
Kazuhiro Yamamoto, Atsushi Mizumoto, Kohji Nishimura, Atsushi Uda, Akira Mukai, Kazuhiko Yamashita, Manabu Kume, Hiroo Makimoto, Toshinori Bito, Chikako Nishigori, Tsutomu Nakagawa, Takeshi Hirano, Midori Hirai
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102110 (2014)
Hand-foot skin reaction is a most common multi-kinase inhibitor-related adverse event. This study aimed to examine whether the toxicity of sorafenib and sunitinib for human keratinocytes was associated with inhibiting signal transduction and activato
Externí odkaz:
https://doaj.org/article/8d8febe9ae8d45458b5199c2ca9aadf1
Autor:
Naomi Kiyota, Kazuhiro Yamamoto, Masaaki Tanda, Hironobu Minami, Ikuko Yano, Mamoru Okuno, Midori Hirai, Takeshi Ioroi, Ken-ichi Nibu, Yoshinori Imamura, Ryohei Sasaki, Shiori Aoki
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-8 (2020)
Journal of Pharmaceutical Health Care and Sciences
Journal of Pharmaceutical Health Care and Sciences
Background Oral mucositis frequently occurs in cancer patients treated with chemotherapy and chemoradiotherapy (CRT). This study examined the safety and efficacy of ibuprofen gargle in healthy volunteers and patients with chemotherapy- and concomitan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78f66edd1d4a4e6aa3eaa175f573bb1
http://www.lib.kobe-u.ac.jp/handle_kernel/90009287
http://www.lib.kobe-u.ac.jp/handle_kernel/90009287