The Quality Control of Midecamycin and the Predictive Demarcation between Its Impurities and Components.

Autor: Yu, Mingyan^1,2,3 (AUTHOR), Wang, Weijian^1,2,3 (AUTHOR), Liu, Wenkun^1,2,3 (AUTHOR), Yang, Huiru^1,2,3 (AUTHOR), Sun, Tong^1,2,3 (AUTHOR), Zhao, Haiyun^1,2,3 (AUTHOR), Chen, Dejun^1,2,3 (AUTHOR) sdyjcdj@sina.com

Publikováno v: Separations (2297-8739). Aug2022, Vol. 9 Issue 8, p225-225. 15p.

The Quality Control of Midecamycin and the Predictive Demarcation between Its Impurities and Components

Autor: Mingyan Yu, Weijian Wang, Wenkun Liu, Huiru Yang, Tong Sun, Haiyun Zhao, Dejun Chen

Publikováno v: Separations, Vol 9, Iss 8, p 225 (2022)

Midecamycin is a 16-membered macrolide antibiotic. It can inhibit the synthesis of bacterial proteins by blocking up the activity of peptidyl transferase in the 50S ribosome. We used high-resolution mass spectrometry to analyze midecamycin, and quant

Externí odkaz: https://doaj.org/article/1f0d52d9470c4dd5becbbe9b67bc21cd

Midecamycin Is Inactivated by Several Different Sugar Moieties at Its Inactivation Site

Autor: Ru Lin, Li-Li Hong, Zhong-Ke Jiang, Ke-Meng Li, Wei-Qing He, Jian-Qiang Kong

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 23, p 12636 (2021)

Glycosylation inactivation is one of the important macrolide resistance mechanisms. The accumulated evidences attributed glycosylation inactivation to a glucosylation modification at the inactivation sites of macrolides. Whether other glycosylation m

Externí odkaz: https://doaj.org/article/f6e6579bdaef4a53a24dbbfb3a4da958

Three-dimensional Nitrogen-Doped Graphene Aerogel as an Excellent Electrode Material for Highly Sensitive Determination of Midecamycin

Autor: Xie, Yu, Ma, Xue, Yu, Yunhui, Zhou, Peng, Lu, Limin, Peng, Guoying, Huang, Xigen, Liu, Guangbin, Wang, Wenmin, He, Haohua

Publikováno v: In International Journal of Electrochemical Science October 2018 13(10):9618-9629

Midecamycin Is Inactivated by Several Different Sugar Moieties at Its Inactivation Site

Autor: Jian-Qiang Kong, Zhong-Ke Jiang, Li-Li Hong, Wei-Qing He, Ke-Meng Li, Ru Lin

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12636, p 12636 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12636
International Journal of Molecular Sciences

Glycosylation inactivation is one of the important macrolide resistance mechanisms. The accumulated evidences attributed glycosylation inactivation to a glucosylation modification at the inactivation sites of macrolides. Whether other glycosylation m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bc78f37c03bf203085b3f36d8bf415
https://www.mdpi.com/1422-0067/22/23/12636