Age-associated systemic factors change central and peripheral immunity in adult male mice

Autor: van Olst, L., Kamermans, A., van der Pol, S.M.A., Rodríguez, E., Hulshof, L.A., van Dijk, R.E., Vonk, D.N., Schouten, M., Witte, M.E., de Vries, H.E., Middeldorp, J.

Publikováno v: In Brain Behavior and Immunity July 2023 111:395-411

Crossing borders in Alzheimer’s disease: A T cell’s perspective

Autor: van Olst, L., Coenen, L., Nieuwland, J.M., Rodriguez-Mogeda, C., de Wit, N.M., Kamermans, A., Middeldorp, J., de Vries, H.E.

Publikováno v: In Advanced Drug Delivery Reviews September 2022 188

Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice.

Autor: Oshima T; Department of Biomedical Sciences, Section Molecular Neurobiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Kater MSJ; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Huffels CFM; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Wesseling EM; Department of Biomedical Sciences, Section Molecular Neurobiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Middeldorp J; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.; Department of Neurobiology & Aging, Biomedical Primate Research Centre, Rijswijk, The Netherlands., Hol EM; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Verheijen MHG; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Smit AB; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Boddeke EWGM; Department of Biomedical Sciences, Section Molecular Neurobiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark., Eggen BJL; Department of Biomedical Sciences, Section Molecular Neurobiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Publikováno v: Journal of neuroscience research [J Neurosci Res] 2024 Mar; Vol. 102 (3), pp. e25295.

Peptidoglycan accumulates in distinct brain regions and cell types over lifetime but is absent in newborns.

Autor: Zeiher C; Institute of Anatomy, University of Leipzig, Leipzig, Germany. Electronic address: carolin.zeiher@gmail.com., Kuhrt H; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Rifflet A; Institute Pasteur, Université Paris Cité, INSERM U1306, Biology and Genetics of the Bacterial Cell Wall Unit, F-75015 Paris, France., Winter K; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Boon L; JJP Biologics, Warsaw, Poland., Stassart RM; Paul-Flechsig-Institute of Neuropathology, Leipzig, Germany., Nutma E; Biomedical Primate Research Centre (BPRC), Department of Neurobiology and Aging, Rijswijk, Netherlands (The)., Middeldorp J; Biomedical Primate Research Centre (BPRC), Department of Neurobiology and Aging, Rijswijk, Netherlands (The)., Strating IM; University Groningen, University Medical Center Groningen (UMCG), Dept. Pathology & Medical Biology, and MS Center Noord Nederland (MSCNN), Groningen, Netherlands (The)., Boneca IG; Institute Pasteur, Université Paris Cité, INSERM U1306, Biology and Genetics of the Bacterial Cell Wall Unit, F-75015 Paris, France. Electronic address: ivo.gomperts-boneca@pasteur.fr., Bechmann I; Institute of Anatomy, University of Leipzig, Leipzig, Germany. Electronic address: Ingo.Bechmann@medizin.uni-leipzig.de., Laman JD; University Groningen, University Medical Center Groningen (UMCG), Dept. Pathology & Medical Biology, and MS Center Noord Nederland (MSCNN), Groningen, Netherlands (The). Electronic address: j.d.laman@umcg.nl.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2025 Jan; Vol. 123, pp. 799-812. Date of Electronic Publication: 2024 Oct 22.

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