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of 1 077
pro vyhledávání: '"Middaugh, P"'
Autor:
Thayana A. Cruz, Nicholas R. Larson, Yangjie Wei, Natalia Subelzu, Yaqi Wu, Christian Schöneich, Leda R. Castilho, Charles Russell Middaugh
Publikováno v:
Biologics, Vol 4, Iss 3, Pp 294-313 (2024)
During early development of biopharmaceuticals, suboptimal producing clones and production conditions can result in limited quantities of high-purity products. Here we describe a systematic approach, which requires minimal amounts of protein (~10 mg)
Externí odkaz:
https://doaj.org/article/4ce9af17cf744b2d9eec9bbc902b6693
Autor:
Md Sohel Ahmed, Brenda J. Hanley, Corey I. Mitchell, Rachel C. Abbott, Nicholas A. Hollingshead, James G. Booth, Joe Guinness, Christopher S. Jennelle, Florian H. Hodel, Carlos Gonzalez-Crespo, Christopher R. Middaugh, Jennifer R. Ballard, Bambi Clemons, Charlie H. Killmaster, Tyler M. Harms, Joe N. Caudell, Kathryn M. Benavidez Westrich, Emily McCallen, Christine Casey, Lindsey M. O’Brien, Jonathan K. Trudeau, Chad Stewart, Michelle Carstensen, William T. McKinley, Kevin P. Hynes, Ashley E. Stevens, Landon A. Miller, Merril Cook, Ryan T. Myers, Jonathan Shaw, Michael J. Tonkovich, James D. Kelly, Daniel M. Grove, Daniel J. Storm, Krysten L. Schuler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Continued spread of chronic wasting disease (CWD) through wild cervid herds negatively impacts populations, erodes wildlife conservation, drains resource dollars, and challenges wildlife management agencies. Risk factors for CWD have been in
Externí odkaz:
https://doaj.org/article/da63780f247e444897414988daded37d
Autor:
Philip J. Mease, Pamela Young, Lara Fallon, Rajiv Mundayat, Oluwaseyi Dina, Taylor Blachley, Nicole Middaugh, Alexis Ogdie
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 2, Pp 313-329 (2024)
Abstract Introduction Randomized controlled trials have demonstrated tofacitinib efficacy for psoriatic arthritis (PsA); however, real-world effectiveness data are limited. This real-world analysis assessed baseline demographics/disease characteristi
Externí odkaz:
https://doaj.org/article/7cf6d725968f442b82ef8a79b8f60232
Autor:
Leslie R. Harrold, Keith Wittstock, Sheila Kelly, Xue Han, Joe Zhuo, Amy Schrader, Nicole Middaugh, Page C. Moore, Vadim Khaychuk
Publikováno v:
Advances in Rheumatology, Vol 64, Iss 1, Pp 1-11 (2024)
Abstract Background The HLA-DRB1 shared epitope (SE) is a risk factor for the development of rheumatoid arthritis (RA) and the production of anti-citrullinated protein antibodies (ACPAs) in RA patients. Our objective was to examine the real-world eff
Externí odkaz:
https://doaj.org/article/fe935ce0ec0c4b219778878a6c299874
Autor:
Philip J. Mease, Jacqueline O'Brien, Nicole Middaugh, Gregory Kricorian, Scott Stryker, David H. Collier, Alexis Ogdie
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 8, Pp 388-398 (2023)
Objective Real‐world studies assessing treatment response by psoriatic arthritis (PsA) domains are limited. This study aimed to describe the patient characteristics, frequency and combinations of disease domains, disease activity, and patient‐rep
Externí odkaz:
https://doaj.org/article/e7cde6931ae94e99a1ad7f49603618fd
Autor:
Robert M. Tona, Reeti Shah, Kimberly Middaugh, Justin Steve, João Marques, Blair R. Roszell, Cindy Jung
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 93-107 (2023)
For gene therapies to become more accessible and affordable treatment options, process intensification is one possible strategy to increase the number of doses generated per batch of viral vector. Process intensification for lentiviral vector manufac
Externí odkaz:
https://doaj.org/article/32387fd36a6540feb6dcb1faccd9a18e
Publikováno v:
PlosOne, January 30, 2020
Effective treatment strategies exist for substance use disorder (SUD), however severe hurdles remain in ensuring adequacy of the SUD treatment (SUDT) workforce as well as improving SUDT affordability, access and stigma. Although evidence shows recent
Externí odkaz:
http://arxiv.org/abs/1908.00216
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