Výsledky vyhledávání - "Mid-hindbrain"

Akademický článek

Gene expression mapping of the neuroectoderm across phyla – conservation and divergence of early brain anlagen between insects and vertebrates

Autor: Nico Posnien, Vera S Hunnekuhl, Gregor Bucher

Publikováno v: eLife, Vol 12 (2023)

Gene expression has been employed for homologizing body regions across bilateria. The molecular comparison of vertebrate and fly brains has led to a number of disputed homology hypotheses. Data from the fly Drosophila melanogaster have recently been

Externí odkaz: https://doaj.org/article/586a7515c9624ffa86cd670fa38a8ad9

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Akademický článek

Yin Yang 1 is critical for mid-hindbrain neuroepithelium development and involved in cerebellar agenesis

Autor: Xiaonan Dong, Kin Ming Kwan

Publikováno v: Molecular Brain, Vol 13, Iss 1, Pp 1-18 (2020)

Abstract The highly conserved and ubiquitously expressed transcription factor Yin Yang 1 (Yy1), was named after its dual functions of both activating and repressing gene transcription. Yy1 plays complex roles in various fundamental biological process

Externí odkaz: https://doaj.org/article/c7605c5ca37846d3962df58147300adf

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Akademický článek

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs

Autor: A. Alwin Prem Anand, Gonzalo Alvarez-Bolado, Andrea Wizenmann

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

MicroRNAs regulate gene expression at post-transcriptional levels. Some of them appear to regulate brain development and are involved in neurodevelopmental disorders. This has led to the suggestion that the role of microRNAs in neuronal development a

Externí odkaz: https://doaj.org/article/6901f0efed8a4afda090c7410dd91bbb

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Akademický článek

EZH2 Is Essential for Fate Determination in the Mammalian Isthmic Area

Autor: Iris Wever, Cindy M. R. J. Wagemans, Marten P. Smidt

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)

The polycomb group proteins (PcGs) are a group of epigenetic factors associated with gene silencing. They are found in several families of multiprotein complexes, including polycomb repressive complex 2 (PRC2). EZH2, EED and SUZ12 form the core compo

Externí odkaz: https://doaj.org/article/dc428c44da5b46388aed1126d574bef8

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Akademický článek

Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Autor: Alex P. A. Donovan, Tian Yu, Jacob Ellegood, Kimberley L. H. Riegman, Christa de Geus, Conny van Ravenswaaij-Arts, Cathy Fernandes, Jason P. Lerch, M. Albert Basson

Publikováno v: Frontiers in Neuroanatomy, Vol 11 (2017)

Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expres

Externí odkaz: https://doaj.org/article/439318cc93b44ff9878800b26030c3ec

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Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate

Autor: Simone Mesman, Imke G. J. Houwers, Lars von Oerthel, Jianmin Tian, Willemieke M. Kouwenhoven, Marten P. Smidt, Maria Gruppilo, Cindy M. R. J. Wagemans, Joseph Locker

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12663, p 12663 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 22(23):12663. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12663

Nkx2.9 is a member of the NK homeobox family and resembles Nkx2.2 both in homology and expression pattern. However, while Nkx2.2 is required for development of serotonergic neurons, the role of Nkx2.9 in the mid-hindbrain region is still ill-defined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80361e9c0fb3b0cfa55ad1e4ceb2273
https://doi.org/10.3390/ijms222312663

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Kniha

Cerebellar Development and Neurogenesis in Zebrafish

Autor: Kaslin, Jan, Brand, Michael

Cerebellar organization and function have been studied in numerous species of fish. Fish models such as goldfish and weakly electric fish have led to important findings about the cerebellar architecture, cerebellar circuit physiology and brain evolut

Externí odkaz: https://tud.qucosa.de/id/qucosa%3A33555
https://tud.qucosa.de/api/qucosa%3A33555/attachment/ATT-0/

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MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs

Autor: Alwin Prem Anand, A., Alvarez-Bolado, Gonzalo, Wizenmann, Andrea

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c4acd990b8b8c23c28ffcfdf380d93a7
https://www.frontiersin.org/articles/10.3389/fcell.2020.586158/full

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Akademický článek

Developmental disorders of the midbrain and hindbrain

Autor: Anthony James Barkovich

Publikováno v: Frontiers in Neuroanatomy, Vol 6 (2012)

Malformations of the midbrain and hindbrain have become topics of considerable interest in the neurology and neuroscience literature in recent years. The combined advances of imaging, and molecular biology have improved analyses of structures in thes

Externí odkaz: https://doaj.org/article/cba37baae8504898a2d04861d47069a4

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