Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Microtubule disassembly"'
Publikováno v:
EMBO Rep
It has long been thought that microtubule disassembly, one of the earliest cellular events, contributes to neuronal pruning and neurodegeneration in development and disease. However, how microtubule disassembly drives neuronal pruning remains poorly
Autor:
Samara L. Reck-Peterson, Sarah Triclin, Emmanuel Derivery, Jérémie Gaillard, Laurent Blanchoin, Morgan E. DeSantis, Laura Schaedel, Karin John, Zaw Min Htet, Didier Portran, Charlotte Aumeier, Christophe Leterrier, Manuel Théry, Daisuke Inoue
Publikováno v:
Nature Materials
Nature Materials, Nature Publishing Group, 2021, 20, pp.883-891. ⟨10.1038/s41563-020-00905-0⟩
Nature Materials, 2021, 20, pp.883-891. ⟨10.1038/s41563-020-00905-0⟩
Nature materials
Nature Materials (2021)
Nature Materials, Nature Publishing Group, 2021, 20, pp.883-891. ⟨10.1038/s41563-020-00905-0⟩
Nature Materials, 2021, 20, pp.883-891. ⟨10.1038/s41563-020-00905-0⟩
Nature materials
Nature Materials (2021)
International audience; Microtubule instability stems from the low energy of tubulin dimer interactions, which sets the growing polymer close to its disassembly conditions. Molecular motors use ATP hydrolysis to produce mechanical work and move on mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93db195b41efc8dc56d654f02e748710
https://hal.archives-ouvertes.fr/hal-03122126/document
https://hal.archives-ouvertes.fr/hal-03122126/document
Publikováno v:
Trends in Cell Biology. 29:291-297
Large-scale neurite pruning, the developmentally regulated degeneration of axons or dendrites, is an important specificity mechanism during neuronal circuit formation. Pruning is usually restricted to single neurite branches and can occur by local de
Autor:
Hongmin Qin, Jie Tian
Publikováno v:
iScience, Vol 12, Iss, Pp 379-391 (2019)
iScience
iScience
Summary The sensory organelle cilium is involved in sensing and transducing important signaling cascades in almost all cells of our body. These ciliary-mediated pathways affect cellular homeostasis and metabolisms profoundly. However, it is almost co
Imbalance of Total Cellular Nucleotide Pools and Mechanism of the Colchicine-Induced Cell Activation
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1984 Apr . 81(8), 2401-2405.
Externí odkaz:
https://www.jstor.org/stable/23558
CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin Incorporation
Autor:
Aher, Amol, Rai, Dipti, Schaedel, Laura, Gaillard, Jeremie, John, Karin, Liu, Qingyang, Altelaar, Maarten, Blanchoin, Laurent, Thery, Manuel, Akhmanova, Anna, Celbiologie, Sub Cell Biology, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Current Biology, 30(11), 2175. Cell Press
Current Biology-CB
Current Biology-CB, 2020, 30 (11), pp.2175-2183. ⟨10.1016/j.cub.2020.03.070⟩
Current Biology
Current Biology-CB, Elsevier, 2020, 30 (11), pp.2175-2183. ⟨10.1016/j.cub.2020.03.070⟩
Current Biology-CB
Current Biology-CB, 2020, 30 (11), pp.2175-2183. ⟨10.1016/j.cub.2020.03.070⟩
Current Biology
Current Biology-CB, Elsevier, 2020, 30 (11), pp.2175-2183. ⟨10.1016/j.cub.2020.03.070⟩
Summary Microtubules play a key role in cell division, motility, and intracellular trafficking. Microtubule lattices are generally regarded as stable structures that undergo turnover through dynamic instability of their ends [1]. However, recent evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2432f4beec71abf7b9d0fab5b40b58d
https://dspace.library.uu.nl/handle/1874/410286
https://dspace.library.uu.nl/handle/1874/410286
Publikováno v:
Soft matter. 16(12)
Microtubules (MTs) are bio-polymers, composed of tubulin proteins, involved in several functions such as cell division, transport of cargoes within cells, maintaining cellular structures etc. Their kinetics are often affected by chemical modification
Publikováno v:
IEEE Transactions on NanoBioscience. 17:70-77
Beta amyloid ( $\text{A}\beta $ ) peptide, which is a common neuropathological hallmark deposit in the brain of patients with Alzheimer’s disease, typically comprises 39–43 amino acid residues. $\text{A}\beta $ peptides exist as isoforms of $\tex
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