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pro vyhledávání: '"Microtubule Depolymerization"'
Akademický článek
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Akademický článek
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Autor:
Hannah R. Belsham, Hanan M. Alghamdi, Nikita Dave, Alexandra J. Rathbone, Bill Wickstead, Claire T. Friel
Publikováno v:
Open Biology, Vol 12, Iss 8 (2022)
The activity of a kinesin is largely determined by the approximately 350 residue motor domain, and this region alone is sufficient to classify a kinesin as a member of a particular family. The kinesin-13 family are a group of microtubule depolymerizi
Externí odkaz:
https://doaj.org/article/2963415eaa13462580cabf2e44fe6b0d
Autor:
Rui Zheng, Yonglan Du, Xintai Wang, Tailin Liao, Zhe Zhang, Na Wang, Xiumao Li, Ying Shen, Lei Shi, Jianhong Luo, Jun Xia, Ziyi Wang, Junyu Xu
Publikováno v:
eLife, Vol 11 (2022)
Dynamic microtubules play a critical role in cell structure and function. In nervous system, microtubules are the major route for cargo protein trafficking and they specially extend into and out of synapses to regulate synaptic development and plasti
Externí odkaz:
https://doaj.org/article/1bbc07117eeb410eab587f28548200ca
Autor:
Sa Zhou, Qiuling Luo, Zhiyan Nie, Changhui Wang, Wenkang Zhu, Yingxiang Hong, Jun Zhao, Baolei Pei, Wenjian Ma
Publikováno v:
Plants, Vol 12, Iss 6, p 1285 (2023)
The pivotal role of cysteine-rich receptor-like kinases (CRKs) in modulating growth, development, and responses to stress has been widely acknowledged in Arabidopsis. However, the function and regulation of CRK41 has remained unclear. In this study,
Externí odkaz:
https://doaj.org/article/156a0b019c1b47de832084ea72e9160b
Publikováno v:
Cell Division, Vol 14, Iss 1, Pp 1-14 (2019)
Abstract Background A previous screen of a human kinase and phosphatase shRNA library to select genes that mediate arsenite induction of spindle abnormalities resulted in the identification of phosphatidylinositol-5-phosphate 4-kinase type-2 gamma (P
Externí odkaz:
https://doaj.org/article/4a2fe16d877c46418914d6e853a0ece3
Autor:
Julia V. Popova, Gera A. Pavlova, Alyona V. Razuvaeva, Lyubov A. Yarinich, Evgeniya N. Andreyeva, Alina F. Anders, Yuliya A. Galimova, Fioranna Renda, Maria Patrizia Somma, Alexey V. Pindyurin, Maurizio Gatti
Publikováno v:
Cells, Vol 11, Iss 14, p 2127 (2022)
Centrosome-containing cells assemble their spindles exploiting three main classes of microtubules (MTs): MTs nucleated by the centrosomes, MTs generated near the chromosomes/kinetochores, and MTs nucleated within the spindle by the augmin-dependent p
Externí odkaz:
https://doaj.org/article/5a0a4ff4291744c1991cd9ad4ca7b7bf
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 1009 (2022)
Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammatory diseases induces cellular toxicity by increasing the production of reactive oxygen species (ROS) and impairing autophagic flux. In this study, we investigated whethe
Externí odkaz:
https://doaj.org/article/58b7b17be6274b48873e76faf3aee7aa
Autor:
Xiaoli Guo, Xiaodong Cheng
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 12:232-238
Effect of bone marrow mesenchymal stem cells (BMSCs) on the sensitivity of chemotherapy drugs and microRNAs (miRNAs) is still unclear. This study explored the role of miR-140 modified BMSCs in enhancing paclitaxel sensitivity of cervical squamous cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a7b619d46ebb875f9ab1aafc383318
https://doi.org/10.1166/jbt.2022.2883
https://doi.org/10.1166/jbt.2022.2883
Autor:
Chi-I Chang, Cheng-Chih Hsieh, Yung-Shung Wein, Ching-Chuan Kuo, Chi-Yen Chang, Jrhau Lung, Jong-Yuh Cherng, Po-Chen Chu, Jang-Yang Chang, Yueh-Hsiung Kuo
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6386
Salvinal is a natural lignan isolated from the roots of Salvia mitorrhiza Bunge (Danshen). Previous studies have demonstrated its anti-proliferative activity in both drug-sensitive and -resistant cancer cell lines, with IC50 values ranging from 4–1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b9cf914a6e7096990f62e9732043c3