Zobrazeno 1 - 10
of 15 806
pro vyhledávání: '"Microglial"'
Autor:
Lian Yu, Miao-Miao Liu, Mei-Qi Guan, Rui Wang, Xiao-Rong Yang, Xiu-Min Zhang, Jing-Jing Wei, Shu-Fen Wu, Hong Gu, Qiang Fu, Jun-Hong Guo, Yan-Li Li
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Cognitive decline is a critical hallmark of brain aging. Although aging is a natural process, there is significant heterogeneity in cognition levels among individuals; however, the underlying mechanisms remain uncertain. In our study, we cla
Externí odkaz:
https://doaj.org/article/186cd9e959ce454784f5fee5f03cf60d
Autor:
Lushu Chen, HuiYing Zhang, Ying Zhang, Xiumiao Li, MeiHuan Wang, Yaming Shen, Yuan Cao, Yong Xu, Jin Yao
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Retinal neovascularisation is a major cause of blindness in patients with proliferative diabetic retinopathy (PDR). It is mediated by the complex interaction between dysfunctional ganglion cells, microglia, and vascular endothelial cells. No
Externí odkaz:
https://doaj.org/article/9b1f4299fff94ffcb13d3ad1f7c96795
Autor:
Masahiko Mikuni, Kazuhiro Horiuchi, Ayako Ishikura, Soichiro Kimura, Sho Masutani, Shinya Watanabe, Akihiro Mikami, Shuhei Ishikawa, Hisashi Narita, Ichiro Kusumi, Hidenao Sasaki
Publikováno v:
Case Reports in Neurology, Vol 16, Iss 1, Pp 281-287 (2024)
Introduction: This is a case of a 32-year-old woman who developed postpartum depression (PPD). She became anxious and depressive about caring for her child, and the Edinburgh Postnatal Depression Scale (EPDS) test showed a score of 9 at 2 weeks after
Externí odkaz:
https://doaj.org/article/e84ca3c550ec49f8a7b16411ab154c65
Autor:
Zuzanna M. Luczak-Sobotkowska, Patrycja Rosa, Maria Banqueri Lopez, Natalia Ochocka, Anna Kiryk, Anna M. Lenkiewicz, Martin Furhmann, Aleksander Jankowski, Bozena Kaminska
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Microglia (MG) are myeloid cells of the central nervous system that support homeostasis and instigate neuroinflammation in pathologies. Single-cell RNA sequencing (scRNA-seq) revealed the functional heterogeneity of MG in mouse br
Externí odkaz:
https://doaj.org/article/7b63ae1d625e4e7d930374676c4a0f47
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Traumatic brain injury (TBI) affects millions globally, with a majority of TBI cases being classified as mild, in which diffuse pathologies prevail. Two of the pathological hallmarks of TBI are diffuse axonal injury (DAI) and microglial acti
Externí odkaz:
https://doaj.org/article/e777c5de2b35440e8da72527559709c7
Autor:
Danqing Xin, Tingting Li, Yijing Zhao, Xiaofan Guo, Chengcheng Gai, Zige Jiang, Shuwen Yu, Jiao Cheng, Yan Song, Yahong Cheng, Qian Luo, Bing Gu, Dexiang Liu, Zhen Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-27 (2024)
Abstract Ischemic stroke is a common cause of mortality and severe disability in human and currently lacks effective treatment. Neuronal activation and neuroinflammation are the major two causes of neuronal damage. However, little is known about the
Externí odkaz:
https://doaj.org/article/48f0f0ffde7d4110b6587464754b3454
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 6143-6158 (2024)
Lei Wang,1,* Kai Wang,2,* Yuwen Chen,1 Xiaoyu Zhang,1,3 Wenhao Xu,1,3 Zhong Dong,1,3 Yu Wang1,3,4 1Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, 230000, People’s Republic of China
Externí odkaz:
https://doaj.org/article/d2f4bd8e589047d28f38c6090c2341e9
Publikováno v:
Neuroglia, Vol 5, Iss 3, Pp 289-305 (2024)
Alzheimer’s disease (AD) is the most common form of dementia with characteristic biological markers. Clinically, AD presents as declines in memory, reasoning, and decision making, but the loss of memory is particularly associated with hippocampal d
Externí odkaz:
https://doaj.org/article/ca8f449b26554ac98bbf134677aea1d0
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer disease (AD) is a heterogenous and multifactorial disease, and its pathology is partly driven by microglia and their activated phenotype. Brain organoids (BOs) are gaining prominence as a relevant model of the human brai
Externí odkaz:
https://doaj.org/article/42fb4bcc72914191ac8dbebc4e321cdf
Autor:
Kathleen Hatch, Fritz Lischka, Mengfan Wang, Xiufen Xu, Cheryl D. Stimpson, Tara Barvir, Nathan P. Cramer, Daniel P. Perl, Guoqiang Yu, Caroline A. Browne, Dara L. Dickstein, Zygmunt Galdzicki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Due to their interactions with the neurovasculature, microglia are implicated in maladaptive responses to hypobaric hypoxia at high altitude (HA). To explore these interactions at HA, pharmacological depletion of microglia with the colony-st
Externí odkaz:
https://doaj.org/article/f51280faee024a93b5039b6c5fb33143