Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Microglia/drug effects/metabolism"'
Autor:
Katayama, T., Kobayashi, H., Okamura, T., Yamasaki-Katayama, Y., Kibayashi, T., Kimura, Hiroshi, Ohsawa, K., Kohsaka, S., Minami, M.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40813 (2012)
PLoS ONE, Vol 7, Iss 7, p e40813 (2012)
In this study, microglial migration and phagocytosis were examined in mouse organotypic hippocampal slice cultures, which were treated with N-methyl-D-aspartate (NMDA) to selectively injure neuronal cells. Microglial cells were visualized by the expr
Autor:
Marilena Colaianna, Stefania Schiavone, Margherita Zotti, Michel Dubois-Dauphin, Vincent Jaquet, Vincenzo Cuomo, Silvia Sorce, Luigia Trabace, Karl-Heinz Krause
Publikováno v:
Biological Psychiatry, Vol. 66, No 4 (2009) pp. 384-392
Background Social stress leads to oxidative stress in the central nervous system, contributing to the development of mental disorders. Loss of parvalbumin in interneurons is an important feature of these diseases. We studied the role of the superoxid
Publikováno v:
Neurobiology of Aging, Vol. 27, No 11 (2006) pp. 1577-1587
Reactive oxygen species (ROS) and deposition of cleaved products of amyloid precursor protein (APP) are thought to contribute to neuronal loss observed in Alzheimer's disease (AD). The relationship between these factors was studied in a neuroblastoma
Publikováno v:
Neuroreport. 15(6)
In the CNS insulin-like growth factor-1 (IGF-1) enhances survival of neurons, promotes myelin synthesis and acts as a mitogen for microglia. The effects of IGF-1 are regulated by a family of 6 IGF binding proteins (IGFBPs). We investigated mRNA expre