Výsledky vyhledávání - "Microbiology/Immunity to Infections"

Tsetse flies rely on symbiotic Wigglesworthia for immune system development

Autor: Jingwen Wang, Brian L. Weiss, Serap Aksoy

Publikováno v: PLoS Biology, Vol 9, Iss 5, p e1001070 (2011)
PLoS Biology
PLoS Biology, Vol 9, Iss 5, p e1000619 (2011)

Tsetse harbors an obligate symbiont, Wigglesworthia glossinidia, that must be present during larval maturation for the fly's immune system to develop and function properly during adulthood.
Beneficial microbial symbionts serve important function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed6525e8b968ba08556648121ba983a
http://europepmc.org/articles/PMC3104966?pdf=render

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Interleukin-13 Promotes Susceptibility to Chlamydial Infection of the Respiratory and Genital Tracts

Autor: Kenneth W. Beagley, Paul S. Foster, Alison J. Carey, Gerard E. Kaiko, Kelly L. Asquith, Philip M. Hansbro, Jay C. Horvat

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1001339 (2011)

Chlamydiae are intracellular bacteria that commonly cause infections of the respiratory and genital tracts, which are major clinical problems. Infections are also linked to the aetiology of diseases such as asthma, emphysema and heart disease. The cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3745d719d566d1c509a4452627895b33
https://hdl.handle.net/10453/128825

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Host iron withholding demands siderophore utilization for Candida glabrata to survive macrophage killing

Autor: Tracy Nevitt, Dennis J. Thiele

Publikováno v: PLoS Pathogens, Vol 7, Iss 3, p e1001322 (2011)
PLoS Pathogens

The fungal pathogen Candida glabrata has risen from an innocuous commensal to a major human pathogen that causes life-threatening infections with an associated mortality rate of up to 50%. The dramatic rise in the number of immunocompromised individu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeee9c255961809f6fb64933335923d
http://europepmc.org/articles/PMC3060170?pdf=render

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Chemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural host

Autor: Elaine Bennett, Deborah Howarth, David J. Hughes, Jeffery T. Sample, R. Papoula-Pereira, Brian F. Flanagan, James P. Stewart, Joanne A. Cummerson, Gail Leeming, Anja Kipar

Publikováno v: PLoS Pathogens, Vol 7, Iss 3, p e1001321 (2011)
PLoS Pathogens
PLOS PATHOGENS

Murine γ-herpesvirus 68 (MHV-68) infection of Mus musculus-derived strains of mice is an attractive model of γ-herpesvirus infection. Surprisingly, however, ablation of expression of MHV-68 M3, a secreted protein with broad chemokine-binding proper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d937acd08139a9722aafa267d0e1f1
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21445235/pdf/?tool=EBI

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Dynamic imaging of the effector immune response to listeria infection in vivo

Autor: Eric G. Pamer, Huan Zheng, Janelle Waite, Daniel A. Portnoy, Chris S. Rae, Ingrid Leiner, Michael L. Dustin, Peter Lauer, Gaetan Barbet

Publikováno v: PLoS pathogens, vol 7, iss 3
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 3, p e1001326 (2011)
PLoS

Host defense against the intracellular pathogen Listeria monocytogenes (Lm) requires innate and adaptive immunity. Here, we directly imaged immune cell dynamics at Lm foci established by dendritic cells in the subcapsular red pulp (scDC) using intrav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ea52b51118206817f8e1880f39a073
https://escholarship.org/uc/item/618177rh

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Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome

Autor: Peter C. Bull, Britta C. Urban, Lucy B. Ochola, Johnstone Makale, Thomas N. Williams, Alister Craig, Bethsheba R. Siddondo, Eva N Kimani, Tadge Szestak, Harold Ocholla, Anne Liljander, Kevin Marsh, Siana Nkya

Publikováno v: PLoS ONE, Vol 6, Iss 3, p e14741 (2011)
PLoS ONE

Our understanding of the basis of severe disease in malaria is incomplete. It is clear that pathology is in part related to the pro-inflammatory nature of the host response but a number of other factors are also thought to be involved, including the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc7dfea001edcdf132ea7d5f02c8ebd
http://europepmc.org/articles/PMC3048392?pdf=render

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The Danger Signal S100B Integrates Pathogen– and Danger–Sensing Pathways to Restrain Inflammation

Autor: Rosario Donato, Guglielmo Sorci, Francesca Riuzzi, Teresa Zelante, Pierluigi Bonifazi, S. Zagarella, Gloria Giovannini, Luigina Romani, Francesco Bistoni

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 3, p e1001315 (2011)
PLoS Pathogens; Vol 7

Humans inhale hundreds of Aspergillus conidia without adverse consequences. Powerful protective mechanisms may ensure prompt control of the pathogen and inflammation. Here we reveal a previously unknown mechanism by which the danger molecule S100B in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b14cb433f863fcff6d21b124e2a206e
http://europepmc.org/articles/PMC3053348

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Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice

Autor: Mi-Na Kweon, Hyun-Jeong Ko, Baik Lin Seong, Satoshi Uematsu, Hyung-Joon Kwon, Young Ho Byun, Shizuo Akira, Sang Uk Seo

Publikováno v: PLoS Pathogens, Vol 7, Iss 2, p e1001304 (2011)
PLoS Pathogens

Type I interferon (IFN-I) plays a critical role in the homeostasis of hematopoietic stem cells and influences neutrophil influx to the site of inflammation. IFN-I receptor knockout (Ifnar1 −/−) mice develop significant defects in the infiltration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d592e0e87c69f3a021e16c5306577e
http://europepmc.org/articles/PMC3044702?pdf=render

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Molecular basis of increased serum resistance among pulmonary isolates of non-typeable Haemophilus influenzae

Autor: Sarah E. Clark, Timothy F. Murphy, Ankur B. Dalia, Janet R. Gilsdorf, Arnold L. Smith, Jeffery N. Weiser, Mikhail Shchepetov, Shigeki Nakamura, Sanjay Sethi

Publikováno v: PLoS Pathogens, Vol 7, Iss 1, p e1001247 (2011)
PLoS Pathogens

Non-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing isolates from the upper airway, LRT iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb03907eb0455d27519ec2d5bc7bf49a
http://europepmc.org/articles/PMC3017122?pdf=render

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Should the human microbiome be considered when developing vaccines?

Autor: Rosana B. R. Ferreira, L. Caetano M. Antunes, B. Brett Finlay

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 11, p e1001190 (2010)

The human microbiome, especially in the intestinal tract has received increased attention in the past few years due to its importance in numerous biological processes. Recent advances in DNA sequencing technology and analysis now allow us to better d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0176a583e4e5314dcae910b1e77b3854
https://pubmed.ncbi.nlm.nih.gov/21124987

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