Teixobactin kills bacteria by a two-pronged attack on the cell envelope

Autor: Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G.N., Jones, Chelsea R., Vermeulen, Bram J.A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A.M., Bonvin, Alexandre M.J.J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus, Sub NMR Spectroscopy, Sub Membrane Biochemistry & Biophysics, Sub Cell Biology, NMR Spectroscopy, Celbiologie, Membrane Biochemistry and Biophysics

Publikováno v: Nature, 608(7922), 390. Nature Research
Nature
Nature, 608(7922), 390-396. Nature Publishing Group

Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance1–3. Teixobactin4 represents a new class of antibiotics with a unique chemical scaffold and lack of detectable resistance. Teixobactin targets lipid II, a precursor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a758c21eadc4b4daf2806d5db5df77
https://doi.org/10.1038/s41586-022-05019-y

Fecal components modulate human astrovirus infectivity in cells and reconstituted intestinal tissues

Autor: Soner Yildiz, Laurent Kaiser, Gael Vieille, Caroline Tapparel, Lara Turin, Francisco J. Pérez-Rodriguez

Publikováno v: mSphere, Vol. 4, No 6 (2019) pp. e00568-19
mSphere, Vol 4, Iss 6, p e00568-19 (2019)
mSphere
mSphere, Vol 4, Iss 6 (2019)

To ensure transmission, enteric viruses must maintain their infectivity during the various environmental challenges that they face in transit within and between hosts. Increased knowledge of the factors affecting enteric virus survival may help to co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920b7ba1dcafacbe9d3c69d760d6b08c
https://archive-ouverte.unige.ch/unige:139739

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata

Autor: Antonietta Vella, Elena De Carolis, Dominique Sanglard, Enrica Mello, Brunella Posteraro, David S. Perlin, Maurizio Sanguinetti

Publikováno v: Scientific reports, vol. 7, no. 1, pp. 9099
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports

The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients. If “time is of the essence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c666f58a77c0ac7744efee1bf206ea9
https://serval.unil.ch/resource/serval:BIB_26C4A26464DA.P001/REF.pdf

Improved in vitro evaluation of novel antimicrobials:potential synergy between human plasma and antibacterial peptidomimetics, AMPs and antibiotics against human pathogenic bacteria

Autor: Linda Citterio, Henrik Franzyk, Yaseelan Palarasah, Thomas Emil Andersen, Lone Gram, Ramona Valentina Mateiu

Publikováno v: Citterio, L, Franzyk, H, Palarasah, Y, Andersen, T E, Mateiu, R V & Gram, L 2016, ' Improved in vitro evaluation of novel antimicrobials : potential synergy between human plasma and antibacterial peptidomimetics, AMPs and antibiotics against human pathogenic bacteria ', Research in Microbiology, vol. 167, no. 2, pp. 72-82 . https://doi.org/10.1016/j.resmic.2015.10.002

Stable peptidomimetics mimicking natural antimicrobial peptides (AMPs) have emerged as a promising class of potential novel antibiotics. In the present study, we aimed at determining whether the antibacterial activity of two α-peptide/β-peptoid pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b27b414c67ee914898e217d1a1af115
https://portal.findresearcher.sdu.dk/da/publications/9a09f7b1-b852-48ca-b507-3b8671a44412

In vitro activity of gentamicin, vancomycin or amikacin combined with EDTA or l-arginine as lock therapy against a wide spectrum of biofilm-forming clinical strains isolated from catheter-related infections

Autor: David Lebeaux, Jean-Marc Ghigo, Christophe Beloin, Véronique Leflon-Guibout

Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, 2015, 70 (6), pp.1704-1712. ⟨10.1093/jac/dkv044⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2015, 70 (6), pp.1704-1712. ⟨10.1093/jac/dkv044⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2015, 70 (6), pp.1704-1712. 〈10.1093/jac/dkv044〉

Objectives Treatment of catheter-related bloodstream infections (CRBSI) is hampered by the characteristic tolerance of bacterial biofilms towards antibiotics. Our objective was to study the effect of the combination of antibiotics and the alkaline am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe4cbf9db3f2dc7006b3805b35621dc
https://hal-pasteur.archives-ouvertes.fr/pasteur-01378735/file/Post-Print-Lebeauxetal-JAC-2015.pdf