Zobrazeno 1 - 10
of 411
pro vyhledávání: '"MicroRNA-1"'
Autor:
Pengcui Li, Yangyang Gao, Raorao Zhou, Xianda Che, Hang Wang, Lingling Cong, Pinpin Jiang, Dan Liang, Penghua Li, Chunfang Wang, Wenjin Li, Shengbo Sang, Qianqian Duan, Xiaochun Wei
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Our objective in this study is to determine whether intra-articular injection of miRNA-1 can attenuate the progression of OA in rats by down regulating Ihh. Knee chondrocytes were isolated from male Sprague–Dawley rats aged 2–3 days. Sec
Externí odkaz:
https://doaj.org/article/13a25d5ad879446a84683df405096490
Autor:
Kittipong Maneechotesuwan, MD, PhD, Nattakarn Prapruetkit, MD, Jirabhorn Chankham, MD, Jirawat Assawabhumi, BS, Kanda Kasetsinsombat, MSc, Peter J. Barnes, FRS, FMedSci
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100238- (2024)
Background: Thymic stromal lymphopoietin (TSLP) orchestrates eosinophilic inflammation, which may increase during asthma exacerbations. In contrast, microRNA-1 (miR-1) inhibits TSLP-mediated eosinophil trafficking in lung endothelium. Whether the bal
Externí odkaz:
https://doaj.org/article/31e4ac3bf4674567a66055406213c05b
Autor:
Arevik Ghazaryan, Jared A. Wallace, William W. Tang, Cindy Barba, Soh-Hyun Lee, Kaylyn M. Bauer, Morgan C. Nelson, Carissa N. Kim, Chris Stubben, Warren P. Voth, Dinesh S. Rao, Ryan M. O’Connell
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Acute myeloid leukemia (AML) is a heterogeneous and deadly disease characterized by uncontrolled expansion of malignant blasts. Altered metabolism and dysregulated microRNA (miRNA) expression profiles are both characteristic of AML. However, there is
Externí odkaz:
https://doaj.org/article/7398a18c853e402d9edaebb274d37ba5
Akademický článek
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Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 11, Iss 4, Pp 719-727 (2021)
Purpose: Myocardial infarction (MI), known as a multifactorial disease, remains the predominant cause of mortality and sudden deaths annually. The current study aimed to measure the expression of microRNA-1 and microRNA-221-3p in MI patients. Methods
Externí odkaz:
https://doaj.org/article/a9dd50199b184af3928d0334bfa7c336
Autor:
Ligia M. Antunes‐Correa, Patricia F. Trevizan, Aline V.N. Bacurau, Larissa Ferreira‐Santos, João L.P. Gomes, Ursula Urias, Patricia A. Oliveira, Maria Janieire N.N. Alves, Dirceu R. deAlmeida, Patricia C. Brum, Edilamar M. Oliveira, Ludhmila Hajjar, Roberto Kalil Filho, Carlos Eduardo Negrão
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 1, Pp 89-102 (2020)
Abstract Background The exercise intolerance in chronic heart failure with reduced ejection fraction (HFrEF) is mostly attributed to alterations in skeletal muscle. However, the mechanisms underlying the skeletal myopathy in patients with HFrEF are n
Externí odkaz:
https://doaj.org/article/68a9d1c662894318928186b7ce730491
Akademický článek
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Akademický článek
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Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 14, Pp 1357-1364 (2019)
Objective To investigate the therapeutic effect of intravenous administration of a microRNA-1 (miR-1) agomir on isoproterenol (ISO)-induced heart failure (HF) in mice. Methods Mouse models of HF were established by intraperitoneal injection of ISO fo
Externí odkaz:
https://doaj.org/article/9fe8bae2365a4560bf7c0fce9fbd8c4e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 1406-1410 (2019)
Prostate cancer (PC) is known as the most common cancer and is ranked second in cancer-related deaths in males. Accumulating evidence implicates microRNAs (miRNAs) may play key roles in tumorigenesis. We investigated the effects of microRNA-1 (miR-1)
Externí odkaz:
https://doaj.org/article/d6697995bd64423c98db1838e3790ec4