Zobrazeno 1 - 10
of 1 272
pro vyhledávání: '"MicroPET"'
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background Parkinson’s disease (PD) is a prevalent neurodegenerative disorder worldwide, diagnosed based on classic symptoms like motor dysfunction and cognitive impairments. With the development of various radioactive ligands, positron em
Externí odkaz:
https://doaj.org/article/c96453cdd74e4bdaa28b72f83bd6f1af
Autor:
Brígida Gomes de Almeida Schirmer, Isabela Conceição Duarte Dornelas, Letícia de Avelar Ferreira, João Vitor Reis Marques, Mariana Duarte de Souza, Marina Barcelos de Miranda, Pollyana Ribeiro Castro, Jousie Michel Pereira, Luciola Da Silva Barcelos, Carlos Malamut
Publikováno v:
Brazilian Journal of Radiation Sciences, Vol 12, Iss 4 (2024)
Positron emission tomography (PET) is one of the most sensitive and effective imaging techniques for detecting very low concentrations of specific radiotracers. It is suitable for analyzing biochemical, metabolic, physiological and functional informa
Externí odkaz:
https://doaj.org/article/317a29e410644971895bbd88cf6b1d2c
Autor:
Xiaoliang Shao, Yaqi Liu, Mingge Zhou, Min Xu, Yuqi Chen, Hongbo Huang, Jianguo Lin, Yuetao Wang
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Purpose To use 18 F-FDG microPET dynamic imaging to preliminarily identify the changes of myocardial glucose metabolism corresponding to different functional phenotypes of diabetic cardiomyopathy (DCM) in mice and elucidate their relationshi
Externí odkaz:
https://doaj.org/article/0683fce42f654e869c674672c7d938a1
Autor:
Santhoshi P. Palandira, Joseph Carrion, Lauren Turecki, Aidan Falvey, Qiong Zeng, Hui Liu, Tea Tsaava, Dov Herschberg, Michael Brines, Sangeeta S. Chavan, Eric H. Chang, An Vo, Yilong Ma, Christine N. Metz, Yousef Al-Abed, Kevin J. Tracey, Valentin A. Pavlov
Publikováno v:
Bioelectronic Medicine, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background Brain metabolic alterations and neuroinflammation have been reported in several peripheral inflammatory conditions and present significant potential for targeting with new diagnostic approaches and treatments. However, non-invasiv
Externí odkaz:
https://doaj.org/article/f6eb8380ba334652af35af0a18d0e5a6
Akademický článek
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Autor:
Hui Nie, Nian Wang, Jinwen Huang, Zhuang Ni, Kangyan Xue, Lixing Song, Mingwei Wang, Fanhong Wu
Publikováno v:
SynOpen, Vol 06, Iss 02, Pp 80-85 (2022)
Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imagin
Externí odkaz:
https://doaj.org/article/33b1815f00c04ca48b7f03e20d1865f7
Autor:
Javier Andrés Muñiz, Carolina Lucía Facal, Leandro Urrutia, Ramiro Clerici-Delville, Ana Damianich, Juan E. Ferrario, Germán Falasco, María Elena Avale
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Tau is a microtubule-associated protein predominantly expressed in neurons, which participates in microtubule polymerization and axonal transport. Abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, such as Alzheimer’s di
Externí odkaz:
https://doaj.org/article/36ed0e9e232c4960b582dd1a46c7cdb2
Autor:
Helen Crehan, Bin Liu, Martin Kleinschmidt, Jens-Ulrich Rahfeld, Kevin X. Le, Barbara J. Caldarone, Jeffrey L. Frost, Thore Hettmann, Birgit Hutter-Paier, Brian O’Nuallain, Mi-Ae Park, Marcelo F. DiCarli, Inge Lues, Stephan Schilling, Cynthia A. Lemere
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-19 (2020)
Abstract Background Pyroglutamate-3 Aβ (pGlu-3 Aβ) is an N-terminally truncated and post-translationally modified Aβ species found in Alzheimer’s disease (AD) brain. Its increased peptide aggregation propensity and toxicity make it an attractive
Externí odkaz:
https://doaj.org/article/a0a62adb0fd742e6bf4a5334e028d25a
Akademický článek
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Autor:
Francesco Cicone, Silvano Gnesin, Thibaut Denoël, Thierry Stora, Nicholas P. van der Meulen, Cristina Müller, Christiaan Vermeulen, Martina Benešová, Ulli Köster, Karl Johnston, Ernesto Amato, Lucrezia Auditore, George Coukos, Michael Stabin, Niklaus Schaefer, David Viertl, John O. Prior
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Biodistribution studies based on organ harvesting represent the gold standard pre-clinical technique for dose extrapolations. However, sequential imaging is becoming increasingly popular as it allows the extraction of longitudinal
Externí odkaz:
https://doaj.org/article/d27a854219804a8a8b595aceb7c71946