Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Micro Report"'
Autor:
Dae Hee Han, Ilgang Hong, Ja Eun Choi, Pojeong Park, Jun-Yeong Baek, HyoJin Park, Soichiro Ide, Masayoshi Mishina, Kazutaka Ikeda, Bong-Kiun Kaang
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Molecular Brain
Molecular Brain
Ketamine, a non-competitive antagonist of the N-methyl-d-aspartate receptor (NMDAR), generates a rapidly-acting antidepressant effect. It exerts psychomimetic effects, yet demands a further investigation of its mechanism. Previous research showed tha
Publikováno v:
Neuropsychopharmacology Reports
Aim Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique that shows potential for treating psychiatric disorders. Although several studies have sought to investigate new TMS modalities for the treatment of various psyc
Publikováno v:
Neuropsychopharmacology Reports
Lithium carbonate is used to increase white blood cell counts as a means of counteracting leukopenia caused by the administration of antipsychotic drugs. To evaluate the effect of antipsychotics on the leukocyte‐enhancing effect of lithium, we comp
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Molecular Brain
Molecular Brain
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease, with no present cure. The progressive loss of MNs is the hallmark of ALS. We have previously shown the therapeutic effects of the phosphatase and tensin homolog (PTEN)
Publikováno v:
Neuropsychopharmacology Reports
Aim Acute N‐methyl‐D‐aspartate (NMDA) receptor antagonism is an important pharmacological animal model of schizophrenia. In previous studies, schizophrenia patients show impaired goal‐directed behavior in an outcome‐specific devaluation pro
Publikováno v:
Neuropsychopharmacology Reports
Butorphanol and buprenorphine are mixed opioid receptor agonist‐antagonist drugs widely used as analgesics in people and animals. There are few reports concerning the interaction of multiple opioids, and their antinociceptive effects, when combined
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-4 (2021)
Molecular Brain
Molecular Brain
The CACNA1H gene encodes the α1 subunit of the low voltage-activated Cav3.2 T-type calcium channel, an important regulator of neuronal excitability. Alternative mRNA splicing can generate multiple channel variants with distinct biophysical propertie
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Molecular Brain
Molecular Brain
Assessment of neural activity in the specific brain area is critical for understanding the circuit mechanisms underlying altered brain function and behaviors. A number of immediate early genes (IEGs) that are rapidly transcribed in neuronal cells in
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-4 (2021)
Molecular Brain
Molecular Brain
T-type calcium channels are important regulators of neuronal excitability. The mammalian brain expresses three T-type channel isoforms (Cav3.1, Cav3.2 and Cav3.3) with distinct biophysical properties that are critically regulated by temperature. Here
Publikováno v:
Neuropsychopharmacology Reports
Aim We previously demonstrated that intracerebroventricular injection of resolvin D2 (RvD2), a bioactive lipid mediator derived from docosahexaenoic acid, ameliorated depression‐like behavior in lipopolysaccharide‐induced and chronic mild stress