Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Micol E Fiori"'
Autor:
Sara Vitale, Federica Calapà, Francesca Colonna, Francesca Luongo, Mauro Biffoni, Ruggero De Maria, Micol E. Fiori
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract The process of drug discovery and pre‐clinical testing is currently inefficient, expensive, and time‐consuming. Most importantly, the success rate is unsatisfactory, as only a small percentage of tested drugs are made available to oncolo
Externí odkaz:
https://doaj.org/article/b1c1a802e30c4ca2b5e141e98fe956c8
Autor:
Laura Fontana, Micol E Fiori, Sonia Albini, Loredana Cifaldi, Serena Giovinazzi, Matteo Forloni, Renata Boldrini, Alberto Donfrancesco, Valentina Federici, Patrizio Giacomini, Cesare Peschle, Doriana Fruci
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2236 (2008)
We identified a key oncogenic pathway underlying neuroblastoma progression: specifically, MYCN, expressed at elevated level, transactivates the miRNA 17-5p-92 cluster, which inhibits p21 and BIM translation by interaction with their mRNA 3' UTRs. Ove
Externí odkaz:
https://doaj.org/article/437f2f409d9c42eeb5fcacc071668e90
Autor:
Marta Moretti, Anna Citarella, Claudia Sabato, Enrico De Smaele, Zein Mersini Besharat, Francesca Gianno, Sofia Trocchianesi, Micol E. Fiori, Alessandra Vacca, Agnese Po, Giuseppina Catanzaro, Elisabetta Ferretti
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Colorectal cancer (CRC) is a leading cause of cancer death. Chemoresistance is a pivotal feature of cancer cells leading to treatment failure and ATP-binding cassette (ABC) transporters are responsible for the efflux of several molecules, including a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd10eb5a77eeeb3281d650b119115ca
http://link.springer.com/article/10.1038/s41598-020-70871-9
http://link.springer.com/article/10.1038/s41598-020-70871-9
Autor:
Paola Bianca, Melania Lo Iacono, Laura Rosa Mangiapane, Micol E. Fiori, Maria Rita Bongiorno, Matilde Todaro, Luca Fagnocchi, Sven Beyes, Michele Signore, Veronica Veschi, Miriam Gaggianesi, Jan Paul Medema, Gaspare Gulotta, Irene Pillitteri, Annalisa Nicotra, Alice Turdo, Simone Di Franco, Ruggero De Maria, Gloria Ganduscio, Davide Stefano Sardina, Alessio Zippo, Giorgio Stassi
Publikováno v:
Gut, 71(1), 119-128. BMJ Publishing Group
ObjectiveCancer stem cells are responsible for tumour spreading and relapse. Human epidermal growth factor receptor 2 (HER2) expression is a negative prognostic factor in colorectal cancer (CRC) and a potential target in tumours carrying the gene amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac3cf44e52a8889d307bbba5462dd05
http://hdl.handle.net/10447/472524
http://hdl.handle.net/10447/472524
Autor:
Miriam Gaggianesi, Jan Paul Medema, Laura Rosa Mangiapane, Marzia Mare, Davide Stefano Sardina, Alice Turdo, Sander R. van Hooff, Dario Giuffrida, Micol E. Fiori, Salvatore Vieni, Maria Rita Bongiorno, Paolo Vigneri, Irene Pillitteri, Veronica Veschi, Simone Di Franco, Eliana Gulotta, Matilde Todaro, Lorenzo Memeo, Melania Lo Iacono, Ruggero De Maria, Lorenzo Colarossi, Vincenzo Luca Lentini, Paola Bianca, Annalisa Nicotra, Gianmarco Motta, Giorgio Giannone, Emanuele Martorana, Giorgio Stassi, Federica Martorana
Publikováno v:
Nature Communications
Nature communications, 12(1):5006. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, 12(1):5006. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Obesity is a strong risk factor for cancer progression, posing obesity-related cancer as one of the leading causes of death. Nevertheless, the molecular mechanisms that endow cancer cells with metastatic properties in patients affected by obesity rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce969dad59268efa180855bb795402e
https://pubmed.ncbi.nlm.nih.gov/34408135
https://pubmed.ncbi.nlm.nih.gov/34408135
Autor:
Chiara Barbini, Lidia Villanova, Cristina Piccolo, Alessandra Boe, Ruggero De Maria, Micol E. Fiori
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 7
International Journal of Molecular Sciences, Vol 21, Iss 2423, p 2423 (2020)
Volume 21
Issue 7
International Journal of Molecular Sciences, Vol 21, Iss 2423, p 2423 (2020)
MicroRNAs are tiny but powerful regulators of gene expression at the post-transcriptional level. Aberrant expression of oncogenic and tumor-suppressor microRNAs has been recognized as a common feature of human cancers. Colorectal cancer represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea34f5706cd3bdb1a62c48a27609c09e
Autor:
Filomena Colella, Federica Calapà, Federica Carbone, Luigi Perelli, Ruggero De Maria, Micol E. Fiori, Donatella Lucchetti, Alessandro Sgambato, Claudio Ricciardi-Tenore
Publikováno v:
Cancers
Volume 12
Issue 2
Cancers, Vol 12, Iss 2, p 260 (2020)
Volume 12
Issue 2
Cancers, Vol 12, Iss 2, p 260 (2020)
Cancer cells secrete small extracellular vesicles (sEVs) that are involved in the remodeling of tumor microenvironment (TME) and can promote tumor progression. The role of sEVs and their molecular key players in colon cancer stem cells differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ac09676793b242637edfae2ac46d3d
http://europepmc.org/articles/PMC7072373
http://europepmc.org/articles/PMC7072373
Autor:
Marco Gabbianelli, Ugo Testa, Ornella Morsilli, Elvira Pelosi, Ernestina Saulle, Eleonora Petrucci, Germana Castelli, Serena Giovinazzi, Gualtiero Mariani, Micol E. Fiori, Giuseppina Bonanno, Adriana Massa, Carlo M. Croce, Laura Fontana, Cesare Peschle
Publikováno v:
Haematologica, Vol 95, Iss 8 (2010)
Background The human hemoglobin switch (HbF→HbA) takes place in the peri/post-natal period. In adult life, however, the residual HbF (
Externí odkaz:
https://doaj.org/article/6413d18974c34a93bebccc34cd5d711a
Autor:
Girolamo Cirrincione, Laura Rosa Mangiapane, Giorgio Stassi, Alice Turdo, Irene Pillitteri, Gloria Ganduscio, Veronica Veschi, Micol E. Fiori, Antonino Glaviano, Patrizia Diana, Daniela Carbone, Simone Di Franco, Camilla Pecoraro, Ornella Roberta Brancato, Annalisa Nicotra, Ruggero De Maria, Barbara Parrino, Lorenzo Colarossi, Isabella Screpanti, Stella Cascioferro, Melania Lo Iacono, Miriam Gaggianesi, Paola Bianca, Matilde Todaro, Vincenzo Davide Pantina
Publikováno v:
iScience
iScience, Vol 24, Iss 6, Pp 102664-(2021)
iScience, Vol 24, Iss 6, Pp 102664-(2021)
Summary Limited therapeutic options are available for advanced colorectal cancer (CRC). Herein, we report that exposure to a neo-synthetic bis(indolyl)thiazole alkaloid analog, nortopsentin 234 (NORA234), leads to an initial reduction of proliferativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9184dac40031dfb0aab639a8211ca03
https://doi.org/10.1016/j.isci.2021.102664
https://doi.org/10.1016/j.isci.2021.102664
Autor:
Francesca Colonna, Francesca Luongo, Micol E. Fiori, Federica Calapà, Sara Vitale, Ruggero De Maria
Publikováno v:
Cancers
Cancers, Vol 11, Iss 8, p 1076 (2019)
Cancers, Vol 11, Iss 8, p 1076 (2019)
PTEN is one of the most frequently inactivated tumor suppressor genes in cancer. Loss or variation in PTEN gene/protein levels is commonly observed in a broad spectrum of human cancers, while germline PTEN mutations cause inherited syndromes that lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ad5a741819643a8c6e20508e64e79d
http://europepmc.org/articles/PMC6721423
http://europepmc.org/articles/PMC6721423