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pro vyhledávání: '"Micklefield, J"'
Akademický článek
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Autor:
Le Feuvre RA, Carbonell P, Currin A, Dunstan M, Fellows D, Jervis AJ, Rattray NJW, Robinson CJ, Swainston N, Vinaixa M, Williams A, Yan C, Barran P, Breitling R, Chen GG, Faulon JL, Goble C, Goodacre R, Kell DB, Micklefield J, Scrutton NS, Shapira P, Takano E, Turner NJ
Publikováno v:
Synthetic and Systems Biotechnology, Vol 1, Iss 4, Pp 271-275 (2016)
The UK Synthetic Biology Research Centre, SYNBIOCHEM, hosted by the Manchester Institute of Biotechnology at the University of Manchester is delivering innovative technology platforms to facilitate the predictable engineering of microbial bio-factori
Externí odkaz:
https://doaj.org/article/cb98f7c3b5aa4a4285d27429e52025b6
Autor:
Westley, C, Fisk, H, Xu, Y, Hollywood, KA, Carnell, AJ, Micklefield, J, Turner, NJ, Goodacre, R
Publikováno v:
Chemistry: A European Journal
For enzyme‐catalysed biotransformations, continuous in situ detection methods minimise the need for sample manipulation, ultimately leading to more accurate real‐time kinetic determinations of substrate(s) and product(s). We have established for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::543b4e71d5f0af67f80e3538d83d78b2
http://livrepository.liverpool.ac.uk/3006725/1/UVRR-ChemEuroJ.docx
http://livrepository.liverpool.ac.uk/3006725/1/UVRR-ChemEuroJ.docx
Publikováno v:
Winn, M, Fyans, J, Zhuo, Y & Micklefield, J 2016, ' Recent advances in engineering nonribosomal peptide assembly lines. ', Natural Product Reports, vol. 33, pp. 317-347 . https://doi.org/10.1039/c5np00099h
Covering: up to July 2015Nonribosomal peptides are amongst the most widespread and structurally diverse secondary metabolites in nature with many possessing bioactivity that can be exploited for therapeutic applications. Due to the major challenges a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::e3392c8f2204605acb8cf8a2c3f6008e
https://www.research.manchester.ac.uk/portal/en/publications/recent-advances-in-engineering-nonribosomal-peptide-assembly-lines(cb14e78e-2c2d-47e4-9d68-daee6aa4c989).html
https://www.research.manchester.ac.uk/portal/en/publications/recent-advances-in-engineering-nonribosomal-peptide-assembly-lines(cb14e78e-2c2d-47e4-9d68-daee6aa4c989).html
Autor:
Medema, M., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J., Blin, K., de Bruijn, I., Chooi, Y., Claesen, J., Coates, R., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D., Fewer, D., Garg, N., Geiger, C., Gomez-Escribano, J., Greule, A., Hadjithomas, M., Haines, A., Helfrich, E., Hillwig, M., Ishida, K., Jones, A., Jones, C., Jungmann, K., Kegler, C., Uk Kim, H., Kötter, P., Krug, D., Masschelein, J., Melnik, A., Mantovani, S., Monroe, E., Moore, M., Moss, N., Nützmann, H., Pan, G., Pati, A., Petras, D., Reen, F., Rui, Z., Tian, Z., Tsunematsu, Y., Tobias, N., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A., Balibar, C., Balskus, E., Barona-Gómez, F., Bechthold, A., Bode, H., Borriss, R., Brady, S., Brakhage, A., Caffrey, P., Cheng, Y., Clardy, J., Cox, R., De Mot, R., Donadio, S., van der Donk, W., Dorrestein, P., Doyle, S., Driessen, A., Ehling-Schulz, M., Entian, K., Fischbach, M., Gerwick, L., Gerwick, W., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S., Ju, J., Katz, L., Kaysser, L., Klassen, J., Keller, N., Kormanec, J., Kuipers, O., Kuzuyama, T., Kyrpides, N., Kwon, H., Lautru, S., Lavigne, R., Lee, C., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D., Moore, B., Moreira, L., Müller, R., Neilan, B., Nett, M., Nielsen, J., O’Gara, F., Oikawa, H., Osbourn, A., Osburne, M., Ostash, B., Payne, S., Pernode, J., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J., Salas, J., Schmitt, E., Scott, B., Seipke, R., Shen, B., Sherman, D., Sivonen, K., Smanski, M., Sosio, M., Stegmann, E., Süssmuth, R., Tahlan, K., Thomas, C., Tang, Y., Truman, A., Viaud, M., Walton, J., Walsh, C., Weber, T., van Wezel, G., Wilkinson, B., Willey, J., Wohlleben, W., Wright, G., Ziemert, N., Zhang, C., Zotchev, S., Breitling, R., Takano, E., Glöckner, F.
Publikováno v:
Nature Chemical Biology
A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1874::bec04116e7667f228bbf489be2ba9e5d
https://hdl.handle.net/21.11116/0000-0006-AB82-621.11116/0000-0001-C3FB-8
https://hdl.handle.net/21.11116/0000-0006-AB82-621.11116/0000-0001-C3FB-8
This work was supported by BBSRC grant BB/I012648/1, Manchester Centre for Synthetic Biology (SynBioChem) BB/M017702/1, and a BBSRC Ph.D. studentship (for J.L.). The EPSRC provided a Ph.D. studentship (for P.T.L.). Re-engineered riboswitches that no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::483f231190eff38307257c87339e3ed3
http://pubs.acs.org/doi/suppl/10.1021/jacs.5b03405
http://pubs.acs.org/doi/suppl/10.1021/jacs.5b03405
Akademický článek
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Publikováno v:
In Comprehensive Chirality 2012:402-429
Akademický článek
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