Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mickey R Miller"'
Autor:
Marta W Szulik, Steven Valdez, Maureen Walsh, Kathryn Davis, Ryan Bia, Emilee Horiuchi, Sean O'Very, Anil Laxman, Linda Nicolova, Hanin Sheikh, Samuel Hickenlooper, Mickey R Miller, Li Wang, June Garcia-Llano, Christopher Tracy, Stavros G Drakos, Katsuhiko Funai, Dipayan Chaudhuri, Sihem Boudina, Sarah Franklin
Publikováno v:
Circulation Research. 131
The histone lysine methyltransferase SMYD1 has been shown to be critical for embryonic cardiac development and in maintaining cardiomyocyte homeostasis in adult mice. Subsequently, we reported that loss of Smyd1 in the adult mouse myocardium leads to
Autor:
Nephi A. Walton, Brent Hafen, Sara Graceffo, Nykole Sutherland, Melanie Emmerson, Rachel Palmquist, Christine M. Formea, Maricel Purcell, Bret Heale, Matthew A. Brown, Christopher J. Danford, Sumathi I. Rachamadugu, Thomas N. Person, Katherine A. Shortt, G. Bryce Christensen, Jared M. Evans, Sharanya Raghunath, Christopher P. Johnson, Stacey Knight, Viet T. Le, Jeffrey L. Anderson, Margaret Van Meter, Teresa Reading, Derrick S. Haslem, Ivy C. Hansen, Betsey Batcher, Tyler Barker, Travis J. Sheffield, Bhaskara Yandava, David P. Taylor, Pallavi Ranade-Kharkar, Christopher C. Giauque, Kenneth R. Eyring, Jesse W. Breinholt, Mickey R. Miller, Payton R. Carter, Jason L. Gillman, Andrew W. Gunn, Kirk U. Knowlton, Joshua L. Bonkowsky, Kari Stefansson, Lincoln D. Nadauld, Howard L. McLeod
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 11; Pages: 1867
The clinical use of genomic analysis has expanded rapidly resulting in an increased availability and utility of genomic information in clinical care. We have developed an infrastructure utilizing informatics tools and clinical processes to facilitate
Autor:
Maureen Walsh, Sarah Franklin, Katsuhiko Funai, Garcia-Llano June, Marta W. Szulik, Ryan Bia, Anil Laxman, Dipayan Chaudhuri, Mickey R. Miller, Emilee Horiuchi, Christopher M. Tracy, Sihem Boudina, Steven Valdez, Sean A. O’Very, Li Wang, Kathryn Davis, Stavros G. Drakos
Publikováno v:
Circulation Research. 129
SMYD1a, a myosin-specific histone lysine methyltransferase, plays a major role in regulating disease-induced remodeling in the adult heart. Previously, we demonstrated that the inducible loss of this chromatin-bound enzyme is sufficient to induce car
Autor:
Mickey R. Miller, Allen R. Buskirk
Publikováno v:
Frontiers in Microbiology, Vol 5 (2014)
In bacteria, transfer-messenger RNA (tmRNA) and SmpB comprise the most common and effective system for rescuing stalled ribosomes. Ribosomes stall on mRNA transcripts lacking stop codons and are rescued as the defective mRNA is swapped for the tmRNA
Externí odkaz:
https://doaj.org/article/4be75364e5f846a88c4851ec49eb51dc
Autor:
Sarah Franklin, Marta W. Szulik, Kristi L. Russell, Mickey R. Miller, Junco S. Warren, June Garcia, Li Wang, Christopher M. Tracy, Aman Makaju
Publikováno v:
Current Opinion in Physiology. 1:140-152
Protein methylation plays a pivotal role in the regulation of various cellular processes including chromatin remodeling and gene expression. SET and MYND domain-containing proteins (Smyd) are a special class of lysine methyltransferases whose catalyt
Publikováno v:
Circulation Research. 125
Heart failure is one of the most devastating conditions that contributes to 25% of all deaths in the USA every year. The development of heart failure, which is often preceded by cardiac hypertrophy resulting from an increased workload, is accompanied
Autor:
Oliver Fiehn, Yong Hwan Han, Li Wang, Bucky K. Lozier, Alexey V. Zaitsev, Keiko M. Cawley, Haley O. Tucker, Dane W. Barton, Shin Ichi Oka, Tatiana Yuzyuk, Marta W. Szulik, Sihem Boudina, Aman Makaju, James E. Cox, Sarah Franklin, Anil Kumar, Christopher M. Tracy, June García Llana, Junco S. Warren, Amira D. Sabry, Mickey R. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 33
Smyd1, a muscle-specific histone methyltransferase, has established roles in skeletal and cardiac muscle development, but its role in the adult heart remains poorly understood. Our prior work demonstrated that cardiac-specific deletion of Smyd1 in ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfe9f171a6775148864dc3039a20f75
https://escholarship.org/uc/item/40v3856w
https://escholarship.org/uc/item/40v3856w
Autor:
Allen R. Buskirk, Mickey R. Miller
Publikováno v:
RNA. 20:228-235
In bacteria, ribosomes stalled on truncated mRNAs are rescued by transfer-messenger RNA (tmRNA) and its protein partner SmpB. Acting like tRNA, the aminoacyl-tmRNA/SmpB complex is delivered to the ribosomal A site by EF-Tu and accepts the transfer of
Autor:
Alexey V. Zaitsev, Mickey R. Miller, Sarah Franklin, Dane W. Barton, Junko S Warren, James E. Cox, Li Wang, Tatiana N Yuzyuk
Publikováno v:
Circulation Research. 119
Epigenetic control of metabolism in the healthy and diseased heart remains poorly understood. We recently demonstrated that chromatin-bound Smyd1, a muscle-specific histone methyltransferase, is significantly upregulated in a mouse model of pressure
Autor:
Allen R. Buskirk, Hani S. Zaher, Steven R. Herron, Mickey R. Miller, Zhu Liu, Rachel Green, DeAnna J. Cazier, Grant M. Gebhard
Publikováno v:
RNA. 17:1727-1736
In bacteria, stalled ribosomes are recycled by a hybrid transfer–messenger RNA (tmRNA). Like tRNA, tmRNA is aminoacylated with alanine and is delivered to the ribosome by EF-Tu, where it reacts with the growing polypeptide chain. tmRNA entry into s