Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mickael Montembault"'
Autor:
Emily Jarvis, Robert Wilson, Claudia Leemereise, Jon Robertson, Gordon J. Dear, Edith M. Hessel, Maki Mizuma, Jan De Backer, Mickael Montembault, J. Nicole Hamblin, Wilfried De Backer, Wim Vos, Cedric Van Holsbeke, Malcolm Begg, Yi Cui, Anthony Cahn
Publikováno v:
International journal of chronic obstructive pulmonary disease
International Journal of Chronic Obstructive Pulmonary Disease
International Journal of Chronic Obstructive Pulmonary Disease
Anthony Cahn,1 J Nicole Hamblin,2 Jon Robertson,3 Malcolm Begg,2 Emily Jarvis,3 Robert Wilson,1 Gordon Dear,4 Claudia Leemereise,5 Yi Cui,6 Maki Mizuma,7 Mickael Montembault,8 Cedric Van Holsbeke,9 Wim Vos,9 Wilfried De Backer,10 Jan De Backer,9 Edit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad618ea8058f0343f510aead0b3f5610
https://www.dovepress.com/an-inhaled-pi3k-inhibitor-improves-recovery-in-acutely-exacerbating-co-peer-reviewed-fulltext-article-COPD
https://www.dovepress.com/an-inhaled-pi3k-inhibitor-improves-recovery-in-acutely-exacerbating-co-peer-reviewed-fulltext-article-COPD
Autor:
Mickael Montembault, Robert Wilson, Emily Jarvis, J. Nicole Hamblin, Anthony Cahn, Edith M. Hessel
Publikováno v:
Clinical Therapeutics. 40:1410-1417
Purpose Novel therapies to treat chronic obstructive pulmonary disease are highly desirable. The safety, tolerability, and pharmacokinetic (PK) parameters of nemiralisib, a phosphoinositide 3-kinase δ inhibitor, administered via the Ellipta dry powd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d34e3006e299c3e7453eb1025dee398
https://doi.org/10.1016/j.clinthera.2018.06.011
https://doi.org/10.1016/j.clinthera.2018.06.011
Autor:
Rainard Fuhr, L. Dunsire, Julie Nicole Hamblin, Anne Kirsten, Anthony Cahn, Claudia Leemereise, Henrik Watz, Edith M. Hessel, Srividya Sriskantharajah, L. Galinanes-Garcia, Robert Wilson, Mickael Montembault, Malcolm Begg
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 46:69-77
Background While current therapies reduce symptoms in chronic obstructive pulmonary disease (COPD) patients, substantial unmet need remains and novel treatments are highly desired. Phosphoinositide 3-kinase δ (PI3Kδ) is a lipid kinase specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c0e59dadda6c6b0a5753acd38d2ed4
https://doi.org/10.1016/j.pupt.2017.08.008
https://doi.org/10.1016/j.pupt.2017.08.008
Autor:
Claudia Leemereise, Edith M. Hessel, Shuying Yang, Annabel Hogg, J. Nicole Hamblin, Andrea Ludwig-Sengpiel, Jon Robertson, Oliver Kornmann, Sanjeev Khindri, Mickael Montembault, Anthony Cahn, Yi Cui, Hannah Wajdner, Malcolm Begg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 367(3)
Phosphoinositide 3-kinase δ (PI3Kδ) is a lipid kinase involved in leukocyte recruitment and activation. Activation of PI3Kδ has been linked to airway inflammation and asthma pathogenesis. This randomized, double-blind, placebo-controlled, crossove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c74573c52a1163a28caf2a191302b7
https://pubmed.ncbi.nlm.nih.gov/30217958
https://pubmed.ncbi.nlm.nih.gov/30217958
Autor:
Anthony Cahn, Nicole Hamblin, Mickael Montembault, Emily Jarvis, Edith M. Hessel, Robert Wilson
Publikováno v:
Airway Pharmacology and Treatment.
Introduction: GSK2269557 was investigated in a single centre, three part, double blind (charcoal open-label), placebo controlled trial in healthy subjects following inhaled delivery. Safety, tolerability and plasma PK of single (100 and 200 µg) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::139e29fb3d0449d31cdaa3ee9624bd18
https://doi.org/10.1183/1393003.congress-2017.pa520
https://doi.org/10.1183/1393003.congress-2017.pa520
Autor:
Mickael Montembault, Noushin Brealey, Francis Warren, Rashmi Mehta, Anshita Gupta, Alison Moore
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 29(4)
The Mini Spacer has been developed for use with Ventolin(®) metered dose inhalers (MDIs) to improve accessibility to affordable spacers in developing countries. To ensure patient safety is not compromised if the Mini Spacer is used off-label with fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fad232e9905e59f57646e95a3d3d521
https://pubmed.ncbi.nlm.nih.gov/26824933
https://pubmed.ncbi.nlm.nih.gov/26824933
Publikováno v:
QSAR & Combinatorial Science. 24:712-721
Why is GlaxoSmithKline (GSK) interested in Microsystems Technology (MST) and how can MST be utilised in organic synthesis and biological screening for lead optimisation? The highly competitive world of the drug market forces pharmaceutical companies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2cad58c30cfb4b2d3f74810be65d3c5
https://doi.org/10.1002/qsar.200440001
https://doi.org/10.1002/qsar.200440001
Publikováno v:
Tetrahedron Letters. 43:8091-8094
We have developed a route to the synthesis of new six-membered ring bicyclic nucleoside analogues. The synthesis of 4′-C, 3′-O bicyclic thymidine analogues is presented as first examples of this new family. Six-membered ring construction was effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f7686762ae2f4dc3e4b4c7ca9bea0b
https://doi.org/10.1016/s0040-4039(02)01926-3
https://doi.org/10.1016/s0040-4039(02)01926-3
Autor:
Christophe Pannecouque, Valérie Fargeas, Mickael Montembault, Grant R. Campbell, Erik De Clercq, Vo-Thanh Giang, Myriam Witvrouw, Jean-Marie Peloponese, Jennifer D. Watkins, Jacques Lebreton, Didier Esquieu, James N. Sturgis, Sandrine Opi, Catherine Grégoire, Erwann Loret, Jean de Mareuil, Monique Villiéras, Jean-Pierre Dunot
Publikováno v:
Scopus-Elsevier
Tat is a regulatory HIV-1 protein, which has the particularity to be secreted very early by HIV-infected cells. The extra cellular roles of Tat are suspected to be the main cause of the maintenance of reservoirs of HIV-infected cells and the failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9d61e78a62bdd042935eb872666a65