Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Mickaël Michaud"'
Autor:
Jing Zhang, Christina Trojel-Hansen, Jianghuang Wang, Zili Zhang, Xing Wang, Yuhui Qiao, Huike Jiao, Mickaël Michaud, Oliver Kepp, Marja Jäättelä, Guido Kroemer, Qing Zhong
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Many anticancer agents induce apoptosis, mitotic catastrophe or cellular senescence. Here, we report the functional characterization of an experimental inducer of tumor necrosis factor (TNF)-independent necrosis, necrocide-1 (NC1). NC1 (but
Externí odkaz:
https://doaj.org/article/171bde1588a94937a6504c047993c55a
Autor:
Lorenzo Galluzzi, Ilio Vitale, Laura Senovilla, Ken André Olaussen, Guillaume Pinna, Tobias Eisenberg, Aïcha Goubar, Isabelle Martins, Judith Michels, Gueorgui Kratassiouk, Didac Carmona-Gutierrez, Marie Scoazec, Erika Vacchelli, Frederic Schlemmer, Oliver Kepp, Shensi Shen, Maximilien Tailler, Mireia Niso-Santano, Eugenia Morselli, Alfredo Criollo, Sandy Adjemian, Mohamed Jemaà, Kariman Chaba, Claire Pailleret, Mickaël Michaud, Federico Pietrocola, Nicolas Tajeddine, Thibault de La Motte Rouge, Natalia Araujo, Nadya Morozova, Thomas Robert, Hugues Ripoche, Frederic Commo, Benjamin Besse, Pierre Validire, Pierre Fouret, Angélique Robin, Nicolas Dorvault, Philippe Girard, Sébastien Gouy, Patricia Pautier, Nora Jägemann, Ann-Christin Nickel, Sabrina Marsili, Caroline Paccard, Nicolas Servant, Philippe Hupé, Carmen Behrens, Parviz Behnam-Motlagh, Kimitoshi Kohno, Isabelle Cremer, Diane Damotte, Marco Alifano, Øivind Midttun, Per Magne Ueland, Vladimir Lazar, Philippe Dessen, Hans Zischka, Etienne Chatelut, Maria Castedo, Frank Madeo, Emmanuel Barillot, Juergen Thomale, Ignacio Ivan Wistuba, Catherine Sautès-Fridman, Laurence Zitvogel, Jean-Charles Soria, Annick Harel-Bellan, Guido Kroemer
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 257-269 (2012)
Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we identified vitamin B6 metabolism as a central regulator of cisplatin responses in vitro and i
Externí odkaz:
https://doaj.org/article/c962346fede94134a0ec7d5f7e6f4ffd
Autor:
Jing Zhang, Christina Trojel-Hansen, Jianghuang Wang, ZILI ZHANG, Xing Wang, Yuhui Qiao, Huike Jiao, Mickaël Michaud, Oliver Kepp, Lorenzo Galluzzi, Maria Høyer-Hansen, Marja Jäättelä, Guido Kroemer, Qing Zhong
Many anticancer agents induce apoptosis, mitotic catastrophe or senescence. Here, we report the functional characterization of an experimental inducer of TNF-independent necrosis, necrocide-1 (NC1). NC1 (but not its stereoisomer) killed a panel of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2310887c9ec3047ffff147466067ca
https://doi.org/10.21203/rs.3.rs-2090541/v1
https://doi.org/10.21203/rs.3.rs-2090541/v1
Autor:
Nina Choublier, Vanessa Delcroix, Olivier Mauduit, Mickaël Michaud, Jean-Michel Coindre, Jean-Yves Blay, Céline Brulard, Pauline Lagarde, Tom Lesluyes, Gaëlle Pérot, Frédéric Chibon, Lydia Lartigue, Alain Aurias, Jessica Baud
Publikováno v:
Cancers, Vol 11, Iss 1, p 81 (2019)
Cancers
Volume 11
Issue 1
Cancers
Volume 11
Issue 1
Half of soft-tissue sarcomas are tumors with complex genomics, which display no specific genetic alterations and respond poorly to treatment. It is therefore necessary to find new therapeutic targets for these sarcomas. Despite genetic heterogeneity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e2954f23eef2bc6ee89266154eff1a
http://www.mdpi.com/2072-6694/11/1/81
http://www.mdpi.com/2072-6694/11/1/81
Autor:
Guido Kroemer, Oliver Kepp, Guillermo Mariño, A. Ko, Jean-Luc Perfettini, Eric Deutsch, Cyrus Chargari, Laura Senovilla, Kanehisa A, Isabelle Martins, Mickaël Michaud, Delphine Dugue
Publikováno v:
Cell Death and Differentiation
Clinical oncology heavily relies on the use of radiotherapy, which often leads to merely transient responses that are followed by local or distant relapse. The molecular mechanisms explaining radioresistance are largely elusive. Here, we identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171c6bc5950012ecd619ef2a019c4c91
https://doi.org/10.1038/cdd.2013.124
https://doi.org/10.1038/cdd.2013.124
Autor:
Dalil Hannani, Yuting Ma, Erika Vacchelli, Mickaël Michaud, Frédéric Schlemmer, Eric Solary, Laetitia Aymeric, Guido Kroemer, Oliver Kepp, Lorenzo Galluzzi, Laurie Menger, Laurence Zitvogel, Nathalie Droin, Helene Duret, Sandy Adjemian, Takahiro Yamazaki, Heng Yang, Isabelle Martins, Siamon Gordon, Kim Steegh, Mark J. Smyth, Roman Krzysiek, João Paulo Portela Catani, Abdul Qader Sukkurwala, Stephen R. Mattarollo, Philip R. Taylor, Peter van Endert
Publikováno v:
Immunity
Immunity, Elsevier, 2013, 38 (4), pp.729-741. ⟨10.1016/j.immuni.2013.03.003⟩
Immunity, 2013, 38 (4), pp.729-741. ⟨10.1016/j.immuni.2013.03.003⟩
Immunity, Elsevier, 2013, 38 (4), pp.729-741. ⟨10.1016/j.immuni.2013.03.003⟩
Immunity, 2013, 38 (4), pp.729-741. ⟨10.1016/j.immuni.2013.03.003⟩
International audience; The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to efficient antigen presentation to T cells, however, remains a conundr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe296fa843f743ec63fec1e402106aec
Autor:
Guillermo Mariño, Frank Madeo, Lorenzo Galluzzi, Shensi Shen, Isabelle Martins, Alexander Valent, Bastien Job, Mark J. Smyth, Maria Castedo, Gian Maria Fimia, Mickaël Michaud, Francesco Berardinelli, Claire Pailleret, Alfredo Criollo, Vladimir Lazar, Santiago Rello-Varona, Guillaume Pourcher, Mauro Piacentini, Antonella Sistigu, Vichnou Poirier-Colame, Laura Senovilla, Sylvain Ladoire, Ming Li, Sandy Adjemian, Clara Locher, Ilio Vitale, Takahiro Yamazaki, Christoph Ruckenstuhl, Josef M. Penninger, Monique Talbot, Nicole L Messina, Antonio Antoccia, François Ghiringhelli, Verena Sigl, Fabiola Ciccosanti, Guido Kroemer, Mireia Niso-Santano, Maximilien Tailler, Oliver Kepp, Laurence Zitvogel, Alice Boilève, Carlos López-Otín, Didac Carmona-Gutierrez, Christopher J. Chan, Antonio Fueyo
Publikováno v:
Science. 337:1678-1684
Keeping Cancer Cells At Bay Cancer cells are often aneuploid; that is, they have an abnormal number of chromosomes. But to what extent this contributes to the tumorigenic phenotype is not clear. Senovilla et al. (p. 1678 ; see the Perspective by Zane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52143575746bdb7bd641e3741b46924c
https://doi.org/10.1126/science.1224922
https://doi.org/10.1126/science.1224922
Autor:
Mickaël Michaud, Vichnou Poirier-Colame, Mathias T. Rosenfeldt, Abdul Qader Sukkurwala, Sandy Adjemian, Lorenzo Galluzzi, Sylvain Ladoire, Felipe Andreiuolo, Kevin M. Ryan, Isabelle Martins, Guido Kroemer, Eileen White, Laurence Zitvogel, Kariman Chaba
Publikováno v:
Autophagy. 8:1175-1184
Autophagy is an evolutionarily conserved catabolic process that involves the entrapment of cytoplasmic components within characteristic vesicles for their delivery to and degradation within lysosomes. Alterations in autophagic signaling are found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf695029b20d9fac8bec43a3acbdfda
https://doi.org/10.4161/auto.20353
https://doi.org/10.4161/auto.20353
Autor:
Mickaël Michaud, Guillermo Mariño, José M. Fuentes, Mireia Niso-Santano, Lorenzo Galluzzi, Sergio Lavandero, Eugenia Morselli, Gérard Pierron, Alexander V Arkhipenko, Alfredo Criollo, Jean-Christophe Rain, Francis Harper, Shoaib Ahmad Malik, Maria Chiara Maiuri, Jun Ninomiya-Tsuji, Sylvie Lachkar, Guido Kroemer
Publikováno v:
The EMBO Journal. 30:4908-4920
Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 and TAB3), two upstream acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0119ec737d2c721e537814d7210d7fc
https://doi.org/10.1038/emboj.2011.413
https://doi.org/10.1038/emboj.2011.413
Autor:
Isabelle Martins, Mickaël Michaud, Lorenzo Galluzzi, Laurie Menger, Sandy Adjemian, Laura Senovilla, Guido Kroemer, Oliver Kepp, Frédéric Schlemmer, Laurence Zitvogel
Publikováno v:
Annals of the New York Academy of Sciences. 1209:77-82
Phagocytosis is essential for pathogen elimination and for the removal of apoptotic corpses, a process that has been long considered immunologically silent. The phagocytic uptake of apoptotic/necrotic cells involves a plethora of molecules, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7649f481edf756805ad7d1d8bae24269
https://doi.org/10.1111/j.1749-6632.2010.05740.x
https://doi.org/10.1111/j.1749-6632.2010.05740.x