Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mickaël Le Douget"'
Autor:
Holger Sellner, Emilie Chapeau, Pascal Furet, Markus Voegtle, Bahaa Salem, Mickaël Le Douget, Vincent Bordas, Jean‐Marc Groell, Anne‐Laure Le Goff, Christine Rouzet, Thomas Wietlisbach, Thomas Zimmermann, Joseph McKenna, Cara E. Brocklehurst, Patrick Chène, Markus Wartmann, Clemens Scheufler, Joerg Kallen, Gareth Williams, Stephanie Harlfinger, Martin Traebert, Bérengère M. Dumotier, Tobias Schmelzle, Nicolas Soldermann
Publikováno v:
ChemMedChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87689f9fe496e8ff4e8b8008d72b261f
https://doi.org/10.1002/cmdc.202300051
https://doi.org/10.1002/cmdc.202300051
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
PDF file - 1.4MB, Response to NVP-BGJ398; FGFR pathway modulation by NVP-BGJ398; NVP-BGJ398 - predictive features; FGFR2-c3 mRNA expression in cell lines and FGFR2 DNA copy number in tumors; FGF19 DNA copy number in CCLE cell lines and FGFR3 DNA copy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055d71ccbe50a65e308a5319a0af558a
https://doi.org/10.1158/2159-8290.22529469
https://doi.org/10.1158/2159-8290.22529469
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 99K, Kinase activity and selectivity for NVP-BGJ398; CCLE cell lines sensitive to NVP-BGJ398; GeneSet expression signatures; FGFR genetic alterations and concomitant mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394b8c19ed3865b26c4b23f7077d34aa
https://doi.org/10.1158/2159-8290.22529463.v1
https://doi.org/10.1158/2159-8290.22529463.v1
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 56K, High throughput pharmacological screen of BGJ398 in 517 cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2881a9c58817a03993b13427e5d262a1
https://doi.org/10.1158/2159-8290.22529466.v1
https://doi.org/10.1158/2159-8290.22529466.v1
Autor:
Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72eaa7a7b52b189acf9bc634916ec5d3
https://doi.org/10.1002/cmdc.202200514
https://doi.org/10.1002/cmdc.202200514
Autor:
Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
Publikováno v:
ChemMedChem. 17(19)
Inhibition of the YAP-TEAD protein-protein interaction is an attractive therapeutic concept under intense investigation with the objective to treat cancers associated with a dysregulation of the Hippo pathway. However, owing to the very extended surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e849912e1b00046650c0d4b1f52f7eb
https://pubmed.ncbi.nlm.nih.gov/35950546
https://pubmed.ncbi.nlm.nih.gov/35950546
Autor:
Kavitha Venkatesan, Vincent Bordas, Moriko Ito, Yun Zhang, David Thomas, Vito Guagnano, Zhi Chen, Louise Barys, Christelle Stamm, Astrid Pornon, Simon Wöhrle, William R. Sellers, Audrey Kauffmann, Christine D. Wilson, Yao Yao, Thomas Brümmendorf, Francesco Hofmann, L. Alex Gaither, Fang Li, Mickaël Le Douget, John Monahan, Diana Graus-Porta, Jason Borawski, Carlos Garcia-Echeverria
Publikováno v:
Cancer Discovery. 2:1118-1133
Patient stratification biomarkers that enable the translation of cancer genetic knowledge into clinical use are essential for the successful and rapid development of emerging targeted anticancer therapeutics. Here, we describe the identification of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36ca42da44e334c8fce42a8c299c8af
https://doi.org/10.1158/2159-8290.cd-12-0210
https://doi.org/10.1158/2159-8290.cd-12-0210
Autor:
Simon Woehrle, Diana Graus Porta, William R. Sellers, Fang Li, John Monahan, Yun Zhang, Mickaël Le Douget, Christelle Stamm, Yao Yao, Jason Borawski, Francesco Hofmann, Moriko Ito, Alex Gaither, Vincent Bordas, Kavitha Venkatesan, Christine D. Wilson, Audrey Kauffmann, Thomas Brümmendorf, Vito Guagnano, Zhi Chen
Publikováno v:
Cancer Research. 72:854-854
The mammalian fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) family comprises 22 FGF ligands, which exert their action through 4 highly conserved transmembrane tyrosine kinase receptors (FGFR1, FGFR2, FGFR3 and FGFR4). This hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede832d2320b7b6c9787ca343bea9205
https://doi.org/10.1158/1538-7445.am2012-854
https://doi.org/10.1158/1538-7445.am2012-854
Autor:
François Radvanyi, Pascal Furet, Carsten Spanka, Diana Graus Porta, Katherine Rendahl, Markus Wartmann, Peter Drueckes, Vincent Bordas, Dirksen E. Bussiere, Vito Guagnano, Herbert A. Schmid, Josef Brueggen, Christelle Stamm, Tinya Abrams, Isabelle Bernard-Pierrot, Mickaël Le Douget
Publikováno v:
Molecular Cancer Therapeutics. 10:B246-B246
The mammalian fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) family comprises 22 FGF ligands, 18 of which exert their action through 4 highly conserved transmembrane tyrosine kinase receptors (FGFR1, FGFR2, FGFR3 and FGFR4). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93443c8120aba4b9108ea51220a2ad5a
https://doi.org/10.1158/1535-7163.targ-11-b246
https://doi.org/10.1158/1535-7163.targ-11-b246